Light- and Electronmicroscopical Studies on the Distribution of Various Cell Types in the Sigmoid Colon of Normal Subjects and in Patients with Crohn’s Disease

  • L. A. Ginsel
  • Helen P. Liepman
  • Irene T. Weterman
Part of the Developments in Gastroenterology book series (DIGA, volume 1)


Studies on the characterization and distribution of cell populations in normal human intestine and in the intestine of patients with Crohn’s disease [CD] are mainly based on light-microscopical investigations. Since light-microscopical studies alone are insufficient for complete characterization and quantification of cell populations, we studied by means of comparative light-microscopical [LM] and electron-microscopical [EM] photomontages the distribution of cell populations in the sigmoid colon for normal controls and for patients with CD.


Ulcerative Colitis Plasma Cell Schwann Cell Lamina Propria Sigmoid Colon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Donnellan WL. (1965) The structure of the colonic mucosa. Gastroenterology 49:496–513PubMedGoogle Scholar
  2. 2.
    Eidelman S, Lagunoff D. (1972) The morphology of the normal human rectal biopsy. Hum.Pathol. 3:389–401PubMedCrossRefGoogle Scholar
  3. 3.
    Nagle GJ, Kurtz SM. (1967) The electron microscopy of the human rectal mucosa. Am.J.Dig.Dis. 12:541–567PubMedCrossRefGoogle Scholar
  4. 4.
    Binder V. (1970) Cell density in lamina propria of the colon: A quantitative method applied to normal subjects and ulcerative colitis patients. Scand.J.Gastroenterol. 5:485–490PubMedGoogle Scholar
  5. 5.
    Korelitz BI, Sommers SC. (1974) Differential diagnosis of ulcerative colitis and granulomatous colitis by sigmoidoscopy, rectal biopsy and cell counts of rectal mucosa. Am.J.Gastroenterol. 61:460–469PubMedGoogle Scholar
  6. 6.
    Rotterdam H, Korelitz BI, Sommers SC. (1977) Microgranulomas in grossly normal rectal mucosa in Crohn’s disease. Am.J.Clin.Pathol. 67:550–554PubMedGoogle Scholar
  7. 7.
    Ward M. (1979) Phagocytic function in Crohn’s disease. Z.Gastroenterol. 17:116–124Google Scholar

Copyright information

© Martinus Nijhoff Publishers bv, The Hague 1981

Authors and Affiliations

  • L. A. Ginsel
  • Helen P. Liepman
  • Irene T. Weterman

There are no affiliations available

Personalised recommendations