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Significance of Lip Biopsies in the Diagnosis of Crohn’s Disease [Routine Histology and Immunofluorescence]

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Recent Advances in Crohn’s Disease

Part of the book series: Developments in Gastroenterology ((DIGA,volume 1))

Abstract

Macroscopic oral lesions have been described in 4–9% of patients with Crohn’s disease and ulcerative colitis (1). More recently apparently disease specific immunofluorescent changes have been found in biopsies of macroscopically normal mouths in Crohn’s patients (2). The present study was carried out to compare the histology of macroscopically uninvolved oral mucosa and minor salivary glands from Crohn’s patients, with that from patients with ulcerative colitis and also normal controls. We have also tried to determine the disease specificity of the immunofluorescence staining.

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References

  1. Basu MK, Asquith P. (1980) Oral manifestations of inflammatory bowel disease. In: Clinics in Gastroenterology. Inflammatory Bowel Disease. Ed. Farmer RG. Saunders London. Vol 9. pp. 307–321

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  2. Walker JEG. (1978) Possible diagnostic test for Crohn’s disease by use of buccal mucosa. Lancet 2:759–760

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  3. Schachter H, Kirsner JB. (1975) Definition of inflammatory bowel disease of unknown aetiology. Gastroenterology 68:591–602

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  4. Chisholm DM, Mason DK. (1968) Labial salivary gland biopsy in Sjögren’s disease. J. Clin. Pathol. 21:656–660

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© 1981 Martinus Nijhoff Publishers bv, The Hague

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Basu, M.K., Chesner, I.M., Thompson, R.A., Asquith, P. (1981). Significance of Lip Biopsies in the Diagnosis of Crohn’s Disease [Routine Histology and Immunofluorescence]. In: Peña, A.S., Weterman, I.T., Booth, C.C., Strober, W. (eds) Recent Advances in Crohn’s Disease. Developments in Gastroenterology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8273-4_11

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  • DOI: https://doi.org/10.1007/978-94-009-8273-4_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8275-8

  • Online ISBN: 978-94-009-8273-4

  • eBook Packages: Springer Book Archive

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