Pathophysiological Role of Taurine in Blood Pressure Regulation in Stroke-Prone Spontaneously Hypertensive Rats (SHR)

  • Yukio Yamori
  • Yasuo Nara
  • Ryoichi Horie
  • Akira Ooshima
  • Walter Lovenberg
Part of the Monographs of the Physiological Society of Philadelphia book series (MPSP, volume 7)


Stroke-prone spontaneously hypertensive rats (SHRSP), which were established by selective breeding (Yamori et al., 1974a; Okamoto et al., 1974), develop severe hypertension and cerebrovascular lesions in more than 90% of the population (Yamori et al., 1976). These SHRSP, as well as spontaneously hypertensive rats (SHR), are regarded as the best models to date for studies on the pathogenesis and prevention of the spontaneously developing hypertensive diseases observed in man (Yamori and Okamoto, 1974; Folkow et al., 1973).


Severe Hypertension Pathophysiological Role High Protein Diet Stroke Incidence Intraventricular Injection 
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Copyright information

© Spectrum Publications, Inc. 1981

Authors and Affiliations

  • Yukio Yamori
  • Yasuo Nara
  • Ryoichi Horie
  • Akira Ooshima
  • Walter Lovenberg

There are no affiliations available

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