Abstract
It is well established that calcium serves as the coupler of excitation and contraction in muscle (Dhalla et al., 1977; Katz, 1977; Langer, 1976; and Williamson and Schaffer, 1976). The calcium necessary for maximal contraction appears to be derived from two calcium pools. Pool I calcium is supplied from the extracellular fluid and enters the cell during the plateau phase of the action potential. This pool is thought to be located on the sarcolemmal membrane (Langer, 1978; Limas, 1977; and Williamson et al., 1975). Pool II calcium appears to be separate from the sarcolemma since the calcium in this pool does not rapidly exchange with calcium from the extracellular space unless the muscle is stimulated. Most investigators feel that this latter pool is associated with the terminal cisternae of the sarcoplasmic reticulum.
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Schaffer, S.W., Chovan, J., Kramer, J., Kulakowski, E. (1981). The Role of Taurine Receptors in the Heart. In: Schaffer, S.W., Baskin, S.I., Kocsis, J.J. (eds) The Effects of Taurine on Excitable Tissues. Monographs of the Physiological Society of Philadelphia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8093-8_20
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DOI: https://doi.org/10.1007/978-94-009-8093-8_20
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