Historical review and introduction

  • D. G. Melrose


In this introduction I apologize for being unashamedly nationalistic, for while open heart surgery is very properly a worldwide affair and is particularly the result of North American skill, determination and investment, we in Britain can claim a useful share in its pioneering, particularly in regard to cardiopulmonary bypass and anaesthesia. If we take our starting-point from the first clinical use of a heart-lung machine by Clarence Dennis and others in 19511, you will note that Britain is represented by the sixth recorded case in the world and the fourth survivor (Table 1).


Circulatory Arrest Historical Review Potassium Citrate Bubble Oxygenator Profound Hypothermia 
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© MTP Press Limited 1981

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  • D. G. Melrose

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