Abstract
Enhanced excretion of orotic acid was observed under different physiological [209,210] and nutritional [211–217] conditions. The amount of orotic acid excreted during human pregnancy is about 20–40 mg per day and does not vary substantially during the course of pregnancy [209,210]. Inherited deficiencies of the urea cycle [218], purine nucleoside Phosphorylase [219], and especially of orotate phosphoribosyltransferase and orotidylic acid decarboxylase also result in an increased excretion of orotic acid.
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Čihák, A., Reutter, W. (1980). Alterations in Orotic Acid Excretion. In: Orotic Acid. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8043-3_5
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DOI: https://doi.org/10.1007/978-94-009-8043-3_5
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