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Pathway of Pyrimidine Synthesis de Novo

  • Alois Čihák
  • Werner Reutter

Abstract

Higher organisms and many micro-organisms do not require exogenous pyrimidines and can synthesize pyrimidine nucleotides from simple precursors. In 1944 it became apparent that orotic acid is involved in the synthesis of pyrimidines de novo and a few years later it was evident that it is a precursor of nucleic acids [70,71].

Keywords

Salvage Pathway Orotic Acid Carbamoyl Phosphate Carbamoyl Phosphate Synthetase Pyrimidine Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© A. Čihák and W. Reutter 1980

Authors and Affiliations

  • Alois Čihák
    • 1
  • Werner Reutter
    • 2
  1. 1.Institute of Organic Chemistry and BiochemistryCzechoslovakia Academy of Sciences PragueCzechoslovakia
  2. 2.Institut für Molekularbiologie und Biochemie der Freien UniversitätBerlinGermany

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