The Subunits of Cytochrome C Oxidase

  • Howard S. Mason
Conference paper
Part of the NATO Advanced Study Institutes Series book series (ASIC, volume 89)

Abstract

Cytochrome c oxidase, the key to aerobic life, has been the subject of a number of excellent recent reviews written from general points of view (e.g., 1–14) and there is no need for another. However, within the last five years it has become apparent that the structures and functions of the subunits that comprise the enzyme hold the secrets to ultimate organization of the enzyme, its biosynthesis and assembly, and its overall functions in electron transfer, proton pumping, and reduction of O2 to water in the context of mitochondrial structure. The subunits have proved to be difficult experimental materials with which to obtain results consistent from laboratory to laboratory. What is really established about them? and what remains to be accomplished?

Keywords

Migration Arthritis Peroxide Glycerol Urea 

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Copyright information

© D. Reidel Publishing Company 1982

Authors and Affiliations

  • Howard S. Mason
    • 1
  1. 1.Department of BiochemistrySchool of Medicine Oregon Health Science UniversityPortland OregonUSA

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