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Evaluation of a Mass Detector for HPLC Determination of Organic Compounds in Water

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Analysis of Organic Micropollutants in Water
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Summary

According to its manufacturers, the ACS 750/14 Mass Detector is totally mass responsive for compounds of molecular weight exceeding 250, and could therefore fill an outstanding requirement in the field of HPLC detection of non-volatile organic compounds. The instrument has been assessed in an HPLC system developed to concentrate and resolve organics from aqueous samples in the 0.1-1.0 µg/l range. Its behaviour during both isocratic and gradient elution has been studied, as well as its performance with various water-miscible solvents and HPLC columns. Preliminary work has shown that it may prove to be a valuable asset for HPLC detection when placed in series after a UV absorbance/ fluorescence monitor.

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References

  1. MACRAE, R., and DICK, J. Analysis of carbohydrates using the mass detector. J. Chromatogr. 210 (1981), 138–145.

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  2. CHARLESWORTH, J. M. Evaporative Analyser as a Mass Detector for Liquid Chromatography. Anal. Chem. 50 (11): 1414–1420 (9178).

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© 1982 ECSC, EEC, EAEC, Brussels and Luxembourg

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Connor, K.J., Waggott, A. (1982). Evaluation of a Mass Detector for HPLC Determination of Organic Compounds in Water. In: Bjørseth, A., Angeletti, G. (eds) Analysis of Organic Micropollutants in Water. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7804-1_22

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  • DOI: https://doi.org/10.1007/978-94-009-7804-1_22

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-7806-5

  • Online ISBN: 978-94-009-7804-1

  • eBook Packages: Springer Book Archive

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