Pacemaker Mechanisms

  • Paul F. Cranefield
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 17)


Our hosts, Drs. Bouman and Jongsma, have asked me to summarize the different mechanisms by which spontaneous activity might arise in a cluster of cells, adding that, in their view, a cluster of cells must be taken as the model rather than the single cell to allow for the possible role of reentry as a mechanism for spontaneous activity. In response to their suggestion, I will point out a few ways in which a cell or a collection of cells could serve as a pacemaker and consider some ways in which the rate of such a pacemaker might be varied.


Rhythmic Activity Pacemaker Cell Atrial Cell Purkinje Fiber Circus Movement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Martinus Nijhoff Publishers, The Hague 1982

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  • Paul F. Cranefield

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