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New Directions for Medical Research in Inflammatory Bowel Disease

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Inflammatory Bowel Diseases

Part of the book series: Developments in Gastroenterology ((DIGA,volume 3))

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Abstract

This section of the Symposium--new directions for future research-- is separated into medical, surgical, and experimental aspects. Yet this separation is actually somewhat arbitrary and even artificial. In fact, these three categories of medical, surgical, and experimental research often converge. One example of this convergence is the study of the ideal human experimental model for Crohn’s disease --namely, the postoperative patient.

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References

  1. Greenstein AJ, Sachar DB,Paaternack BS, et al: Reoperation and recurrence in Crohn’s colitis and ileocolitis: crude and cumulative rates. N Engl J Med 293: 685–690, 1975.

    Article  PubMed  CAS  Google Scholar 

  2. Lock MR, Farmer RG, Fazio VW, et al: Recurrence and reoperation for Crohn’s disease: the role of disease location in prognosis. N Engl J Med 304: 1586–1588, 1981.

    Article  PubMed  CAS  Google Scholar 

  3. Wolfson DM,Sachar DB, Cohen A, et al: Do granulomas affect the rate of postoperative recurrence of Crohn’s disease? (abstract). Gastroenterology 80: 1319, 1981.

    Google Scholar 

  4. Farmer RG, Michener WM, Mortimer EA: Studies of family history among patients with inflammatory bowel disease. Clinics in Gastroenterol 9: 271–278, 1981.

    Google Scholar 

  5. Greenstein AJ, Janowitz HD, Sachar DB: The extra-intestinal complications of Crohn’s disease and ulcerative colitis: a study of 700 patients. Medicine 5: 401–412, 1976.

    Article  Google Scholar 

  6. Finkel SI, Janowitz HD: Trauma and the pyoderma gangrenoserum of inflammatory bowel disease. Gut 22: 410–412, 1981.

    Article  PubMed  CAS  Google Scholar 

  7. Wiesner RJ, La Russo NF: Clinicopathologic features of the syndrome of primary sclerosing cholangitis•Gastroenterology 79: 200–206, 1980.

    CAS  Google Scholar 

  8. Greenstein AJ, Sachar DB, Smith H, et al: Comparision of Cancer risk in Crohn’s disease and ulcerative colitis. Cancer: in press, 1981.

    Google Scholar 

  9. Sachar DB, Greenstein AJ: Cancer in ulceratiLe colitis: Good news and bad news (editorial). Ann Intern Med 96: in press, 1981.

    Google Scholar 

  10. Summers RW, Switz DM, SessionsJT, et al: National Cooperative Crohn’s Disease Study: results of drug treatment. Gastroenterology 77: 847–869, 1979.

    PubMed  CAS  Google Scholar 

  11. Present DH, Korelitz BI, Wisch N, et al: Treatment of Crohn’s disease with 6-mercaptopurne a long-term, randomized, double-blind study. N Engl J Med 302: 981–987, 1980.

    Article  PubMed  CAS  Google Scholar 

  12. Bernstein LH, Frank MS, Brandt LJ, et al: Healing of perineal Crohn’s disease with metronidazole. Gastroenterology 79: 357–365, 1980.

    PubMed  CAS  Google Scholar 

  13. Sachar DB: Metronidazole for Crohn’s disease–breakthrough or ballyhoo? (editorial). Gastroenterology 79: 393–395, 1980.

    PubMed  CAS  Google Scholar 

  14. Moss AA, Carbone JV, Kressel HY: Radiologic and clinical assessment of broad spectrum antibiotic therapy in Crohn’s disease. Am J Roentgenol 131: 787, 1978.

    CAS  Google Scholar 

  15. Willoughby CP, Piris J, Truelove SC: The effect of topical N-acetyl-5-aminosalicylic acid in ulcerative colitis. Scand J Gastroenterol 15: 715–719, 1980.

    Article  PubMed  CAS  Google Scholar 

  16. Klotz U, Maier K, Fischer C et al: Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn’s disease. N Engl J Med 303: 1499–1502, 1980.

    Article  PubMed  CAS  Google Scholar 

  17. Strickland RG, Sachar DB; The immunology of inflammatory bowel disease, In Jerzy Glass GB (ed): Progress in Gastroenterology, vol. III. W.B. Saunders, 1977, pp. 821–838.

    Google Scholar 

  18. Meyers S, Sachar DB, Taub RN, et al: Significance of anergy to dinitrochlorobenzene(DNCB) in inflammatory bowel disease: family and postoperative studies. Gut 19: 249–252, 1978.

    Article  PubMed  CAS  Google Scholar 

  19. Sachar DB, Auslander MD, Walfish JS: Aetiological theories of inflammatory bowel disease. Clinics in Gastroenterol 9: 231–257, 1981.

    Google Scholar 

  20. Sachar DB, Present DH: Immunotherapy of inflammatory bowel disease. Med Clin N Amer 62: 173–183, 1978.

    PubMed  CAS  Google Scholar 

  21. Truelove SC (ed): Definition and assessment of activity (symposium). In Pena AS, Weterman IT, Barth CC, et al. (eds) Recent Advances in Crohn’s Disease (Proceedings of the 2nd International Workshop on Crohn’s Disease)

    Google Scholar 

  22. Martinus Nijhoff Publishers, the Hague, 1981,, pp. 1–39.

    Google Scholar 

  23. Meyers S, Walfish JS, Sachar DB, et al: Quality of life after surgery for Crohn’s disease: a psychosocial survey. Gastroenterology 78: 1–6, 1980.

    PubMed  CAS  Google Scholar 

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© 1982 Martinus Nijhoff Publishers, The Hague

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Sachar, D.B. (1982). New Directions for Medical Research in Inflammatory Bowel Disease. In: Rachmilewitz, D. (eds) Inflammatory Bowel Diseases. Developments in Gastroenterology, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7514-9_25

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  • DOI: https://doi.org/10.1007/978-94-009-7514-9_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-7516-3

  • Online ISBN: 978-94-009-7514-9

  • eBook Packages: Springer Book Archive

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