Epidemiology of Gastrointestinal Lymphomas

  • Clark W. HeathJr
Part of the Developments in Oncology book series (DION, volume 6)

Abstract

The gastrointestinal tract and its system of lymphatic drainage are commonly involved in cases of human lymphoma. Over half of all autopsied lymphoma cases examined by Rosenberg et al. (1) showed such abdominal involvement. In less than 5 percent of cases, however, did the disease appear clinically to have originated in gastrointestinal or gastrointestinal lymphoid tissue. Primary gastrointestinal lymphoma is generally, therefore, a rare disease. Although direct measurements of lymphoma incidence exist only by histologic type and not by organ system (overall rates being in the range of 50 to 100 cases per million population per year in most countries (2)), incidence of primary gastrointestinal lymphomas can be estimated at about 2 to 5 cases per million per year.

Keywords

Lymphoma Oncol Dermatitis Parkin Nigeria 

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References

  1. 1.
    Rosenberg SA, Diamond HD, Jaslowitz B, Craver LF: Lymphosarcoma: a review of 1269 cases. Medicine 40: 31–84, 1961.PubMedCrossRefGoogle Scholar
  2. 2.
    Doll R, Muir C, Waterhouse J: Cancer incidence in five continents. International Union Against Cancer, Vol 3, 1975.Google Scholar
  3. 3.
    Aisenberg AC: Malignant Lymphoma. New Engl J Med 288: 883–941, 1973.PubMedCrossRefGoogle Scholar
  4. 4.
    Gutensohn N, Cole P: Epidemiology of Hodgkin’s disease. Sem Oncol 7: 92–102, 1980.Google Scholar
  5. 5.
    De-The G: The epidemiology of Burkitt’s lymphoma: evidence for a causal association with Epstein-Barr virus. Epid Rev 1: 32–54, 1979.Google Scholar
  6. 6.
    Henry K, Farrer-Brown G: Primary lymphomas of the gastrointestinal tract. I: Plasma cell tumors. Histopath 1: 53–76, 1977.CrossRefGoogle Scholar
  7. 7.
    Ho F, Gibson B: Gastrointestinal lymphomas in Hong Kong Chinese. Israel J Med Sci 15: 382–385, 1979.PubMedGoogle Scholar
  8. 8.
    Desai PB, Meher-Homji DR, Paymaster JC: Malignant lymphoma: A clinical study of 800 Indian patients. Cancer 18: 25–33, 1965.CrossRefGoogle Scholar
  9. 9.
    Barekat AA, Saidi F, Dutz W: Cancer survey of Soth Iran with special reference to gastrointestinal neoplasms. Int J Cancer 7: 353–363, 1971.PubMedCrossRefGoogle Scholar
  10. 10.
    Modan B, Shani M, Goldman B, Modan M: Incidence of nodal and extranodal malignant lymphoma in Israel: An epidemiological study. Brit J Haemat 16: 53–59, 1969.PubMedCrossRefGoogle Scholar
  11. 11.
    Gideon EM: Primary malignant lymphoma of the digestive tract. Leb Med J 23: 1–10, 1970Google Scholar
  12. 12.
    Kahn LB, Selzer G, Kaschula RDC: Primary gastrointestinal lymphoma — a clinicopathologic study of fifty-seven cases. Amer J Dig Dis 17: 219–232, 1972.PubMedCrossRefGoogle Scholar
  13. 13.
    Owor R: Malignant lymphoma of the gastrointestinal tract in Uganda — a report of 40 cases. East Afr Med J 54: 666–669, 1977.PubMedGoogle Scholar
  14. 14.
    Allen AW, Donaldson G, Sniffen RC, Goodale F Jr: Primary malignant lymphoma of the gastrointestinal tract. Ann Surg 140: 428–438, 1954.PubMedCrossRefGoogle Scholar
  15. 15.
    Loehr WJ, Mujahed Z, Zahn FD, et al.: Primary lymphoma of the gastrointestinal tract: A review of 100 cases. Ann Surg 170: 232–238, 1969.PubMedCrossRefGoogle Scholar
  16. 16.
    Naqui MS, Burrows L, Kark AE: Lymphoma of the gastrointestinal tract: prognostic guides based on 162 cases. Ann Surg 170: 221–231, 1969.CrossRefGoogle Scholar
  17. 17.
    Freeman C, Berg JW, Cutler SJ: Occurrence and prognosis of extranodal lymphomas. Cancer 29: 252–260, 1972.PubMedCrossRefGoogle Scholar
  18. 18.
    Lewin KJ, Ranchod M, Dorfmann RF: Lymphoma of the gastrointestinal tract. A study of 117 cases presenting with gastrointestinal disease. Canter 42: 693–707, 1978.Google Scholar
  19. 19.
    Taylor ES: Primary lymphosarcoma of the stomach Ann Surg 110: 200–221, 1939.Google Scholar
  20. 20.
    Friedman AI: Primary lymphosarcoma of the stomach. Amer J Med 26: 783–796, 1959.PubMedCrossRefGoogle Scholar
  21. 21.
    Wychulis AR, Beahrs OH, Woolner LB: Malignant lymphoma of the colon. A study of 69 cases. Arch Surg 93: 215–225, 1966.PubMedGoogle Scholar
  22. 22.
    Glick DD, Soule EH: Primary malignant lymphoma of colon or appendix. Arch Surg 92: 144–151, 1966.PubMedGoogle Scholar
  23. 23.
    Marcuse PM, Stout AP: Primary lymphosarcoma of the small intestine. Analysis of 13 cases and review of the literature. Cancer 3: 459–474, 1950.PubMedCrossRefGoogle Scholar
  24. 24.
    Fy YS, Perzin KH Lymphosarcoma of the small intestine. A clinicopathologic study Cancer 29: 645–659 1972.Google Scholar
  25. 25.
    Faulkner JW, Dockerty MB: Lymphosarcoma of the small intestine. Surg Gyn Obst 95: 76–84, 1952.PubMedGoogle Scholar
  26. 26.
    Al-Saleem T, Zardawi IM: Primary lymphomas of the small intestine in Iraq: a pathological study of 145 cases. Histopath 3: 89–106, 1979.CrossRefGoogle Scholar
  27. 27.
    Shani M, Modan B, Goldman B, et al.: Primary gastrointestinal lymphoma. Israel J Med Sci 5: 1173–1177, 1969.PubMedGoogle Scholar
  28. 28.
    Golden R: The small intestine and diarrhea. Amer J Roentgenol 36: 892–901, 1936.Google Scholar
  29. 29.
    Fairley NH, Mackie FP: The clinical and biochemical syndrome in lymphadenoma and allied diseases involving the mesenteric lymph glands. Brit Med J 1: 375–380, 1937.PubMedCrossRefGoogle Scholar
  30. 30.
    Harris OD, Cooke WT, Thompson H, Waterhouse JAH: Malignancy in adult coeliac disease and idiopathic steatorrhea. Amer J Med 42: 899–912, 1967.PubMedCrossRefGoogle Scholar
  31. 31.
    Austad WI, Cornes JS, Gough KR, et al.: Steatorrhea and malignant lymphoma. The relationship of malignant tumors of lymphoid tissue and coeliac disease. Am J Dig Dis 12: 475–490, 1967.PubMedCrossRefGoogle Scholar
  32. 32.
    Brunt PW, Svicus W, MacLean N: Neoplasia and coeliac syndrome in adults: Lancet 1: 180–184, 1969.PubMedGoogle Scholar
  33. 33.
    Holmes GKT, Stokes PL, Sorahan TM, et al.: Coeliac disease, gluten-free diet, and malignancy. Gut 17: 612–619, 1976.PubMedCrossRefGoogle Scholar
  34. 34.
    Isaacson P, Wright DH: Intestinal lymphoma associated with malabsorption. Lancet 1: 67–70, 1978.PubMedCrossRefGoogle Scholar
  35. 35.
    Brandt L, Hagender B, Norden A, Stenstam M: Lymphoma of the small intestine in adult coeliac disease. Acta Med Scand 204: 467–470; 1978.PubMedCrossRefGoogle Scholar
  36. 36.
    Sleisinger MH, Almy TP, Barr DP: The sprue syndrome secondary to lymphoma of the small bowel. Amer J Med 15: 666–674, 1953.CrossRefGoogle Scholar
  37. 37.
    Benson GD, Kowlessar OD, Sleisinger MH: Adult coeliac disease with emphasis upon response to gluten-free diet. Medicine 43: 1–40, 1964.PubMedCrossRefGoogle Scholar
  38. 38.
    Kent TH: Malabsorption syndrome with malignant lymphoma. Arch Path 78: 97–103, 1964.PubMedGoogle Scholar
  39. 39.
    Spence WJE, Ritchie S: Lymphomas of small bowel and their relationship to idiopathic steatorrhea. Canad J Surg 12: 207–209, 1969.PubMedGoogle Scholar
  40. 40.
    Gjone E, Nordoy A: Dermatitis herpetiformis, steatorrhea, and malignancy. But Med J 1: 610, 1970.CrossRefGoogle Scholar
  41. 41.
    Andersson H, Dotevall G, Mobacken H: Malignant mesenteric lymphoma in a patient with dermatitis herpetiformis, hypochlorhydria, and small-bowel abnormalities. Scand J Gastroent 6: 397–399, 1971.PubMedCrossRefGoogle Scholar
  42. 42.
    Connon JJ, McFarland J, Kelly A, et al.: Acute abdominal complications of coeliac disease. Scand J Gastroent 10: 843–846, 1975.PubMedGoogle Scholar
  43. 43.
    Tonder M, Sorlie D, Kearny MS: Adult coeliac disease. A case with ulceration, dermatitis herpetiformis, and reticulosarcoma. Scand J Gastroent 11: 107–111, 1976.PubMedGoogle Scholar
  44. 44.
    Freeman HJ, Weinstein WM, Schmitka TK, et al.: Primary abdominal lymphoma. Presenting manifestation of celiac sprue or complicating dermatitis herpetiformis. Am J Med 63: 585–594, 1977.PubMedCrossRefGoogle Scholar
  45. 45.
    World Health Organization: Alpha-chain disease and related small-intestinal lymphoma: a memorandum. Bull WHO 54: 615–624, 1976.Google Scholar
  46. 46.
    Ramot B, Shanin N, Bubis JJ: Malabsorption in lymphoma of small intestine. A study of 13 cases. Israel J Med Sci 1: 221–226, 1965.PubMedGoogle Scholar
  47. 47.
    Eidelman S, Parkins RA, Rubin CE: Abdominal lymphoma presenting as malabsorption: A clinico-pathologic study of nine cases in Israel and a review of the literature. Medicine 45: 111–137, 1966.CrossRefGoogle Scholar
  48. 48.
    Seligman M, Danon F, Hurez D, et al.: Alpha-chain disease: a new immunoglobulin abnormality. Science 162: 1396–1397, 1968.CrossRefGoogle Scholar
  49. 49.
    Seligman M, Mihaesco E, Hurez D, et al.: Immunochemical studies in four cases of alpha chain disease. J Clin Investig 48: 2374–2389, 1969.CrossRefGoogle Scholar
  50. 50.
    Stoop JW, Ballieux RE, Hijmans W, Zegers BJM: Alpha-chain disease with involvement of the respiratory tract in a Dutch child. Clin Exp Immunol 9: 625–635, 1971.PubMedGoogle Scholar
  51. 51.
    Florin-Christensen A, Doniach D, Newcomb PB: Alpha-chain disease with pulmonary manifestations. Brit Med J 1: 413–415, 1974.CrossRefGoogle Scholar
  52. 52.
    Cohen HJ, Gonzalvo A, Krook J, et al.: New presentation of alpha heavy chain disease: North American polypoid gastrointestinal lymphoma. Clinical and cellular studies. Cancer 41: 1161–1169, 1978.PubMedCrossRefGoogle Scholar
  53. 53.
    Rappaport H, Ramot B, Hulu N, Park JK: The pathology of so-called Mediterranean abdominal lymphoma with malabsorption. Cancer 29: 1502–1511, 1972.PubMedCrossRefGoogle Scholar
  54. 54.
    Ramot B, Levanon M, Hahn Y, et al.: The mutual clonal origin of the lymphoplasmacytic and lymphoma cell in alpha-heavy chain disease. Clin Exp Immunol 27: 440–445, 1977.PubMedGoogle Scholar
  55. 55.
    Novis BH, Bank S, Marks IN, et al.: Abdominal lymphoma presenting with malabsorption. Quart J Med 40: 521–540, 1971.PubMedGoogle Scholar
  56. 56.
    Levin KJ, Kahn LB, Novis BH: Primary intestinal lymphoma of ‘western’ and `Mediterranean’ type, alpha chain disease and massive plasma cell infiltration. A comparative study of 37 cases. Cancer 38: 2511–2528, 1976.CrossRefGoogle Scholar
  57. 57.
    Novis BH: Primary intestinal lymphoma in South Africa. Israel J Med Sci 15: 386–389, 1979.PubMedGoogle Scholar
  58. 58.
    Jinich H, Rojas E, Webb JA, Keiser JR Jr: Lymphoma presenting as malabsorption. Gastroenterology 54: 421–425, 1968.PubMedGoogle Scholar
  59. 59.
    Bonomo L, Dammacco F, Marano R, Bonomo GM: Abdominal lymphoma and alpha chain disease. Report of three cases. Amer J Med 52: 73–85, 1972.PubMedCrossRefGoogle Scholar
  60. 60.
    Doe WF, Henry K, Hobbs JR et al.: Five cases of alpha chain disease. Gut 13: 947–957, 1972.PubMedCrossRefGoogle Scholar
  61. 61.
    Manousos ON, Economidon JC, Georgiadou DE, et al.: Alpha chain disease with clinical, immunological, and histological recovery. Brit Med J 2: 409–412, 1974.PubMedCrossRefGoogle Scholar
  62. 62.
    Pittman FE, Tripathy K, Isobe T, et al.: 1 gA heavy chain disease. A case detected in the western hemisphere. Amer J Med 58: 424–430, 1975.PubMedCrossRefGoogle Scholar
  63. 63.
    Whicher JT, Ajdukiewicz A, Davies JD: Two cases of alpha chain disease from Nigeria. J Clin Path 30: 678–681, 1977.PubMedCrossRefGoogle Scholar
  64. 64.
    Selzer G, Sacks M, Sherman G, Naggan L: Primary malignant lymphoma of the small intestine in Israel. Israel J Med Sci 15: 390–396, 1979.PubMedGoogle Scholar
  65. 65.
    Corres JS, Smith JC, Southwood WFW: Lymphosarcoma in chronic ulcerative colitis with report of two cases. Brit J Surg 49: 50–53, 1961.CrossRefGoogle Scholar
  66. 66.
    Sataline LR, Mobley EM, Kirkham W: Ulcerative colitis complicated by colonic lymphoma. Gastroenterology 44: 342–347, 1963.PubMedGoogle Scholar
  67. 67.
    Nugent FW, Zuberi S, Bulan MB, Legg MA: Colonic lymphoma in ulcerative colitis: report of four cases. Lahey Clin Fdn Bull 21: 104–111, 1972.Google Scholar
  68. 68.
    Friedman HB, Silver GM, Brown CH: Lymphoma of the colon simulating ulcerative colitis. Amer J Dig Dis 13: 910–917, 1968.PubMedCrossRefGoogle Scholar
  69. 69.
    Pevsner S, Leef F: Childhood abdominal lymphoma in two brothers. Israel J Med Sci 9: 914–917, 1973.Google Scholar
  70. 70.
    Banihashemi A, Nasr K, Hedayatee H, Mortazavee H: Familial lymphoma including a report of familial primary upper small intestinal lymphoma. Blut 26: 363–368, 1973.PubMedCrossRefGoogle Scholar
  71. 71.
    Maurer HS, Gotoff SP, Allen L, Bolan J: Malignant lymphoma of the small intestine in multiple family members. Association with an immunologic deficiency. Cancer 37: 2224–2231, 1976.PubMedCrossRefGoogle Scholar
  72. 72.
    Alsabti EAK: Paraproteinemia in normal family members of eight cases with primary intestinal lymphomas in Iraq. Oncology 35: 68–72, 1978.PubMedCrossRefGoogle Scholar

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© Martinus Nijhoff Publishers, The Hague 1982

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  • Clark W. HeathJr

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