Melanoma of the genitourinary tract

  • Sam D. GrahamJr.
  • Wayne A. ClineJr.
  • John L. Weinerth
Part of the Developments in Oncology book series (DION, volume 5)


Malignant melanoma of the genitourinary tract is a very uncommon disease. Less than 200 primary melanomas of the genitourinary tract have been described in the world literature. Even fewer secondary melanomas of this system have been discovered prior to autopsy. The presenting symptoms of genitourinary melanoma are similar to symptoms of all other genitourinary neoplasms, and, as in other urologic neoplasms, these are usually tumors of the aged. Due to the small number of cases, there is no single large series of patients, and thus no controlled clinical studies of therapeutic modalities versus stage of disease. Despite the lack of such series, the results of most treatments have resulted in uniform failures, and the discovery of this disease usually carries a grim prognosis. This chapter will examine the world’s literature regarding this disease and summarize the collective experiences of all authors in regards to treatment and prognosis.


Primary Melanoma Genitourinary Tract Adrenal Metastasis Female Urethra Blue Nevus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Long GC, Counsellor VS and Dockerty MB: Primary melano-epithelioma of the female urethra: review of the literature: report of 3 cases. J Urol 55:520–529, 1946.PubMedGoogle Scholar
  2. 2.
    Allen AC and Spitz S: Melanoma: diagnosis and prognosis. Cancer 6:1–45, 1953.PubMedCrossRefGoogle Scholar
  3. 3.
    Pack GT, Lenson N and Gerber DN: Regional distribution of moles and melanomas. Arch Surg 65:862–870, 1952.CrossRefGoogle Scholar
  4. 4.
    Dean AL: Tumors of penis, urethra, scrotum and testes. In: Campbell MF (ed) Urology, Vol 3, p 177. WB Saunders, Philadelphia, 1952.Google Scholar
  5. 5.
    Murchison as cited in: Gross SD A System of Surgery, 6th ed, Vol 2, p 834. HC Lea’s, Philadelphia, 1889.Google Scholar
  6. 6.
    Wheelock MC and Clark PJ: Sarcoma of the penis. J Urol 49:478–481, 1943.Google Scholar
  7. 7.
    Johnson DE and Ayala AG: Primary melanoma of penis. Urology 2:174–177, 1973.PubMedCrossRefGoogle Scholar
  8. 8.
    Reid JD: Melanosarcoma of the penis. Cancer 10:359–362, 1957.PubMedCrossRefGoogle Scholar
  9. 9.
    MacDermott EN and Kennedy JD: A case of melanoblastoma of the penis. Br J Surg 43:213–214, 1955.PubMedCrossRefGoogle Scholar
  10. 10.
    Shanin AP: Pigmented Tumors, p 229. Medgiz, Leningrad, 1959.Google Scholar
  11. 11.
    Schneiderman C, Semon MA and Levine RM: Malignant melanoma of the penis. J Urol 93:615–619, 1965.PubMedGoogle Scholar
  12. 12.
    Frontsin MH and Hutcheson JB: Malignant melanoma of the penis: a report of two cases. Br J Urol 41:324–326, 1969.CrossRefGoogle Scholar
  13. 13.
    Gojasejni P and Nitigant P: Malignant melanoma of the penis. Br J Urol 44:143–146, 1972.CrossRefGoogle Scholar
  14. 14.
    Girgis AS, Bergman H, Rosenthal H and Solomon L: Unusual penile malignancies in circumcised Jewish men. J Urol 110:696–702, 1973.PubMedGoogle Scholar
  15. 15.
    Bracken RB and Diokno AC: Melanoma of the penis and the urethra: 2 case reports and review of the literature. J Urol 111:198–200, 1924.Google Scholar
  16. 16.
    Ellis H and White WF: Malignant melanoma of the penis: endolymphatic therapy with 131–I lilipiodol. Br J Surg 55:238–241, 1969.CrossRefGoogle Scholar
  17. 17.
    Khezri AA, Dounis A and Roberts JBM: Primary malignant melanoma of the penis. Two cases and a review of the literature. Br J Urol 51:147–150, 1979.PubMedCrossRefGoogle Scholar
  18. 18.
    Colby FH: Melanotic sarcoma of the penis: report of a case. N Engl J Med 201:924, 1929.CrossRefGoogle Scholar
  19. 19.
    Sirsat MV and Shrikande SS: Malignant melanoma of the penis in Indians (a report of two cases). Indian J Pathol Bacteriol 8:237, 1965.Google Scholar
  20. 20.
    Patoria NK and Junnarker RV: Malignant melanoma of the penis: report of a case. Indian J Cancer 3:37–38, 1966.PubMedGoogle Scholar
  21. 21.
    Frick W and Hall FJ: Generalized multiple pigmented sarcoma originating in the skin. J Am Med Assoc 46:1911–1915, 1906.CrossRefGoogle Scholar
  22. 22.
    Buddington WT, Kickham CJE and Smith WE: An assessment of malignant disease of the penis. J Urol 89:442–449, 1963.PubMedGoogle Scholar
  23. 23.
    Cerimele D: Melanosi precancerosa circoscitta e melanoma maligno: a proposito di un caso localizzato al pene. G Ital Dermatol Sifalol 105:669–678 (as quoted in [37]).Google Scholar
  24. 24.
    Thomas J A and Fenn AS: Malignant melanoma of the penis: a report of a case and a review of the literature. Indian J Pathol Bacteriol 10:372–378, 1967.PubMedGoogle Scholar
  25. 25.
    Battle WH: Report on primary sarcoma of the penis to the Pathology Society of London. Lancet 1:520, 1885.Google Scholar
  26. 26.
    Miner CH: Primary sarcoma of the penis. Univ Med Mag Pa 9:824–834, 1896 (as quoted in [37]).Google Scholar
  27. 27.
    Roberts DI: Massive malignant melanoma of the penis occurring in a Malayan. Br J Surg 39:561–568, 1952.PubMedCrossRefGoogle Scholar
  28. 28.
    Svedenzov EP: Melanoma of the penis. Vopr Onkol 7:88–89, 1961 (as quoted in [37]).Google Scholar
  29. 29.
    Das Gupta T and Grabstald H: Melanoma of the genitourinary tract. J Urol 93:607, 1965.Google Scholar
  30. 30.
    Payra E: Melanom des penis. Dtsch Z Chir 33:221–235, 1899 (as quoted in [37]).CrossRefGoogle Scholar
  31. 31.
    Peters W: Melanosarcoma of the penis in a man of 72. J Urol 16:1–3, 1922.Google Scholar
  32. 32.
    Isnardi: Epithelioma mélanique de la verge. Loire Med 48:218–222, 1928 (as quoted in [37]).Google Scholar
  33. 33.
    Noordenbos W: Melanoma of the penis. Ned Tijdschr Geneeskd 77:1879–1855, 1933 (as quated in [37]).Google Scholar
  34. 34.
    Harrison FG: Malignancy of the penis and urethra. Clinics 3:20–32, 1944.Google Scholar
  35. 35.
    Stefan H: Melanoblastoma of the penis. Rozhl Chir 34:103–109, 1955 (as quoted in [37]).PubMedGoogle Scholar
  36. 36.
    Fischer G: Melanosarkom des penis. Dtsch Z Clin 25:313–322, 1887 (as quoted in [37]).CrossRefGoogle Scholar
  37. 37.
    Tallerman A: Malignant melanoma of the penis. Urol Int 27:66–80, 1972.PubMedCrossRefGoogle Scholar
  38. 38.
    Holmes T: Melanosis of the penis. Trans Pathol Soc London 23:175–177, 1871.Google Scholar
  39. 39.
    Gould AP: A case of melanotic epithelioma of the penis. Lancet 1:438–439, 1880.CrossRefGoogle Scholar
  40. 40.
    Bird G: Primary sarcoma of the penis. Lancet 1:520, 1885.Google Scholar
  41. 41.
    Coley WB and Hoguet JP: Melanotic cancer: a report of 91 cases. Ann Surg 64:206–241, 1916.PubMedCrossRefGoogle Scholar
  42. 42.
    Abrams M: Primary melanoma of the female urethra. J Urol 74:371–374, 1955.PubMedGoogle Scholar
  43. 43.
    Batolo D and D’Aquino S: Melanoma del glande: sera documentabile origine da elementi della guaina nervosa. Arch Ital Pathol Clin Tumori 2:285–302, 1958 (as quoted in [37]).Google Scholar
  44. 44.
    Gentil F, Lima EW and Abrao A: Melanoma de penis: relato de 2 casos. Rev Bras Cir 50:183, 1965 (as quoted in [15]).PubMedGoogle Scholar
  45. 45.
    Cascinelli N: Melanoma maligno del pene. Tumori 55:313, 1969 (as quoted in [15]).PubMedGoogle Scholar
  46. 46.
    Cochran AJ: Malignant melanoma: a review of 10 years experience in Glasgow, Scotland. Cancer 23:1190–1199, 1969.PubMedCrossRefGoogle Scholar
  47. 47.
    Trotskii OA: Melanoma polovogo chlena. Urol Nefrol 36:61, 1971 (as quoted in [15]).Google Scholar
  48. 48.
    Bancheri FR, Gallizia G and Grandinetti C: Un cas de mélanom primitif du pénis. J Urol Nephrol 77:138, 1971 (as quoted in [15]).Google Scholar
  49. 49.
    Baruah BD and Dutta A: Malignant melanoma of the penis. J Indian Med Assoc 62:354–356, 1974.PubMedGoogle Scholar
  50. 50.
    Shanik GD and Tagoe SW: Case report: malignant melanoma of the penis. Ir J Med Sci 145:207–208, 1976.PubMedCrossRefGoogle Scholar
  51. 51.
    Abeshouse BS: Primary and secondary melanoma of the genitourinary tract. South Med J 51:994–1006, 1958.PubMedCrossRefGoogle Scholar
  52. 52.
    Albrecht H: Verh Deutsch Ges Pathol 14:253, 1910 (as quoted in [60]).Google Scholar
  53. 53.
    Campbell MF and Fein MJ: Malignant melanoma of the penile urethra: with a brief review of urethral sarcoma in the male. J Urol 35:573–582, 1936.Google Scholar
  54. 54.
    McKenna CM: Melanoblastoma of the penile urethra. Trans Am Assoc Genitourin Surg 30:401–404, 1937.Google Scholar
  55. 55.
    Shih HE: Melanoma of the urethra. Am J Cancer 36:243–246, 1939.Google Scholar
  56. 56.
    Signorelli E: Tumori primitivi dell’uretra Maschile. Urologia 29:530, 1962 (as quoted in [15]).Google Scholar
  57. 57.
    Chiappino G, Strada R: Malignant melanoma of the male urethra. Cancer 15:121, 1962 (as quoted in [15]).Google Scholar
  58. 58.
    Salm R and Rutter TE: A double primary malignant melanoma of the fossa navicularis. Br J Urol 36:91–96, 1964.PubMedCrossRefGoogle Scholar
  59. 59.
    Guinn GA and Ayala AG: Male urethral cancer: report of 15 cases including a primary melanoma. J Urol 103:176–179, 1970.PubMedGoogle Scholar
  60. 60.
    Geelhoed GW and Meyers GH: Primary melanoma of the urethra. J Urol 109:634–637, 1973.PubMedGoogle Scholar
  61. 61.
    Block NL and Hotchkiss RS: Malignant melanoma of the female urethra: report of a case with five-year survival and review of the literature. J Urol 105:251–255, 1971.PubMedGoogle Scholar
  62. 62.
    Reed CAL: Melanosarcoma of the female urethra; urethrotomy; recovery. Am J Obstet Dis Women Child 34:864–867, 1986.Google Scholar
  63. 63.
    Mundell DE: Melanosarcoma of the female urethra. Kingston Med Q 5:75, 1901.Google Scholar
  64. 64.
    Kustner: In: Kurzes Lehrbuch der Gynäkologie 412, 1917 (as quoted in [71]).Google Scholar
  65. 65.
    Hermann: Melanosarcoma of urethra. Wein Med Wochenschr 1:706, 1917 (as quoted in [71]).Google Scholar
  66. 66.
    Kauffman E: Lehrbuch der Speziellen pathologischen Anatomie für Studierende und Arzte, Band 2, S1139. de Gruyter, Berlin, 1922.Google Scholar
  67. 67.
    Basler: (as quoted in [66]). Original translation was of a woman in Basel, but recent reviews of the subject refer to this person as a patient of Basler.Google Scholar
  68. 68.
    Saenger: Melanosarkom. Monatsschr Geburtshilfe Gynaekol 66:177, 1924 (as quoted in [71]).Google Scholar
  69. 69.
    Koerner J: Eineige Geschwürstprobleme an Hand setener (Melanoma urethrae, struma ovarie carcinomatosa, Pseudomyoma peritonei). Centralbl Gynaekol 51:834, 1927 (as quoted in [71]).Google Scholar
  70. 70.
    Fornero: Monit Ostet Ginecol 3:114, 1931 (as quoted in [79]).Google Scholar
  71. 71.
    McCrea LE: Malignancy of the female urethra. Urol Surv 2:85, 1952.PubMedGoogle Scholar
  72. 72.
    Shaw EC: Primary tumor of the female urethra with metastasis to each ureter. J Urol 34:244–253, 1935.Google Scholar
  73. 73.
    Rosenthal AH: Melanoma of the urethra. Am J Obstet Gynecol 30:115–118, 1935.Google Scholar
  74. 74.
    Newell OU and Serivner WC: Melanoma of the female urethra. Am J Obstet Gynecol 35:328–330, 1938.Google Scholar
  75. 75.
    Kyrle P: Zur Kennt der Malignoma Melanoblastoma der Harnröhre. Z Urol Chir Gynaekol 45:287, 1940 (as quoted in [79]).Google Scholar
  76. 76.
    Savran J, Sayer EA and Schradiack CE: Primary malignant melanoma of the female urethra. Am J Surg 75:743–745, 1948.PubMedCrossRefGoogle Scholar
  77. 77.
    Glenn JF: Malignancy of the female urethra: a report of eight cases. N C Med J 14:201–204, 1953.PubMedGoogle Scholar
  78. 78.
    McBurney RP and Bale GF: Primary malignant melanoma of the female urethra. Surgery 37:973–978, 1935.Google Scholar
  79. 79.
    Limburg VH: Geburtshilfe Frauenheikd 16:75, 1956 (as quoted in [61]).Google Scholar
  80. 80.
    Woodruff JD and Brack CB: Unusual malignancies of the vulvo-urethral region: report of 12 cases. Obstet Gynecol 12:677–686, 1958.PubMedGoogle Scholar
  81. 81.
    Letzerukov MA: Urologiya 27:62, 1962 (as quoted in [61]).Google Scholar
  82. 82.
    Sokal Z: Pol Przegl Chir 34:587, 1962 (as quoted in [61]).PubMedGoogle Scholar
  83. 83.
    Rabon NA: Malignant melanoma developing in a urethral caruncle. J Am Med Women Assoc 19:855–856, 1964.Google Scholar
  84. 84.
    Gillenwater JY and Burros HM: Unusual tumors of the female urethra. Obstet Gynecol 31:617–620, 1968.PubMedCrossRefGoogle Scholar
  85. 85.
    Grabstald H, Hilaris B, Henschke U and Whitmore WF: Cancer of the female urethra. J Am Med Assoc 197:835–842, 1966.CrossRefGoogle Scholar
  86. 86.
    Rutledge FN: Clinical conference on malignant melanoma. Med Times (66):1d–15d, 1977.Google Scholar
  87. 87.
    Kehrer: (as quoted in [80]). Also, see Obstet Gynecol 12:677–686, 1958.Google Scholar
  88. 88.
    Pack GT: The pigmented mole and malignant melanoma. Cancer J Clin 12:11–26, 1962.CrossRefGoogle Scholar
  89. 89.
    Taussig FJ: Cancer of the vulva an analysis of 155 cases. Trans Am Gynecol Soc 65:173–188, 1940.Google Scholar
  90. 90.
    Higgins CC and Worden JG: Cancer of the scrotum. J Urol 62:250–256, 1949.PubMedGoogle Scholar
  91. 91.
    Ray B, Huvos AG, Whitmore WF: Unusual malignant tumors of the scrotum: review of 5 cases. J Urol 108:760–766, 1972.PubMedGoogle Scholar
  92. 92.
    Berry NE and Reese L: Malignant melanoma which had its first clinical manifestations in the prostate gland. J Urol 69:286–290, 1953.PubMedGoogle Scholar
  93. 93.
    Ainsworth AM, Clark WH, Mastrangelo M and Conger KB: Primary malignant melanoma of the urinary bladder. Cancer 37:1928–1936, 1976.PubMedCrossRefGoogle Scholar
  94. 94.
    Knisely RM and Baggentoss AH: Primary melanoma of the adrenal gland. Arch Pathol 42:345–349, 1946.Google Scholar
  95. 95.
    Tannenbaum M: Differential diagnosis in immunopathy III: melanotic lesions of the prostate: blue nevus and prostatic epithelial melanosis. Urology 4:617–621, 1974.PubMedCrossRefGoogle Scholar
  96. 96.
    Nigogosyan G, de la Pava S, Pickren JW and Woodruff MW: Blue nevus of the prostate gland. Cancer 16:1097–1099, 1963.PubMedCrossRefGoogle Scholar
  97. 97.
    Su CT and Prince CL: Melanoma of the bladder. J Urol 87:365–367, 1962.PubMedGoogle Scholar
  98. 98.
    Maclachan WWG: Primary melanosarcoma of the adrenal. J Med Res 33:93–106, 1915.Google Scholar
  99. 99.
    McComb RA and Smith DB: A case of melanotic sarcoma of the adrenal glands with secondary tumor in the bladder. J Urol 30:49–59, 1933.Google Scholar
  100. 100.
    Pappenheimer AM: Malignant melanotic tumor, primary in the adrenals. Proc N Y Pathol Soc 14:173–185, 1914.Google Scholar
  101. 101.
    Smith RM: Bilateral melanotic growth of suprarenal gland. Med J Aust 1:683–684, 1927.Google Scholar
  102. 102.
    Shnyronkova OV: Adrenal melanoblastoma with metastases. Arkh Patol 18:111, 1956 (as quoted in [51]).Google Scholar
  103. 103.
    Baker MR: A pigmental melanoma of the adrenal. Arch Pathol 26:845–852, 1938.Google Scholar
  104. 104.
    Weinstock NI, Willscher MK and Novicki DE: Importance of urinary tract investigation in metastatic malignant melanoma. Urology 10:547–549, 1977.PubMedCrossRefGoogle Scholar
  105. 105.
    Goldstein HM, Kaminisky S, Wallace S and Johnson DE: Urographic manifestations of metastatic melanoma. Radiology 101:801–805, 1974.Google Scholar
  106. 106.
    Yamada T, Itou U, Watanabe Y, Ohashi S: Cytologic diagnosis of malignant melanoma. Acta Cytol 16:70, 1972.PubMedGoogle Scholar
  107. 107.
    Woodard BH, Heker RE and Johnston WW: Cytologic diagnosis of malignant melanoma in urine: a case report. Acta Cytol 22:350–352, 1978.PubMedGoogle Scholar
  108. 108.
    Hajdu SI and Savino A: Cytologic diagnosis of malignant melanoma. Acta Cytol 17:320–327, 1973.PubMedGoogle Scholar
  109. 109.
    Dan AL and Ash JE: Study of the bladder tumors in the Registry of the AUA. J Urol 63:618–621, 1950.Google Scholar
  110. 110.
    Melicow MM: Tumors of the urinary bladder: a clinicopathological analysis of over 2,500 specimens and biopsies. J Urol 74:498–521, 1955.PubMedGoogle Scholar
  111. 111.
    Das Gupta T and Brasfield R: Metastatic melanoma: a clinicopathological study. Cancer 17:1323–1339, 1964.CrossRefGoogle Scholar
  112. 112.
    Ganem EJ and Batal JT: Secondary malignant tumors of the urinary bladder metastatic from primary foci in distant organs. J Urol 75:965–972, 1956.PubMedGoogle Scholar
  113. 113.
    Sheehan E, Greenberg D and Scott R: Metastatic neoplasms of the bladder. J Urol 90:281–284, 1963.PubMedGoogle Scholar
  114. 114.
    Klinger ME: Secondary tumors of the genitourinary tract. J Urol 65:144–153, 1951.PubMedGoogle Scholar
  115. 115.
    Morrow RP, Woolner LB and Emmett JL: Metastatic melanoepithelioma of the urinary bladder: report of a case. J Urol 67:92–94, 1952.PubMedGoogle Scholar
  116. 116.
    Pontes JES and Oldford J: Metastatic breast carcinoma to the urinary bladder. J Urol 104:839–842, 1970.PubMedGoogle Scholar
  117. 117.
    Samellas WM and Marks AR: Metastatic melanoma of the urinary tract. J Urol 85:21–23, 1961.PubMedGoogle Scholar
  118. 118.
    Wheelock MC: Sarcoma of the urinary bladder. J Urol 48:628–634, 1942.Google Scholar
  119. 119.
    Walsh EJ, Ockuly GA, Ockuly EF and Ockuly JJ: Treatment of malignant melanoma of the bladder. J Urol 96:472–478, 1966.PubMedGoogle Scholar
  120. 120.
    Amar AD: Metastatic melanoma of the bladder. J Urol 92:198–200, 1964.PubMedGoogle Scholar
  121. 121.
    Hermann HB: Metastatic tumors of the urinary bladder. J Urol 22:257–273, 1929.Google Scholar
  122. 122.
    Weston PAM: Metastatic melanoma in the bladder and urethra. Br J Surg 51:78–79, 1964.PubMedCrossRefGoogle Scholar
  123. 123.
    Bartone FF: Metastatic melanoma of the bladder. J Urol 91:151, 1964.PubMedGoogle Scholar
  124. 124.
    Milner WA: Conservative treatment of tumors of the bladder:296 cases. J Int Coll Surg 20:566–572, 1953.PubMedGoogle Scholar
  125. 125.
    Silverstein MJ, DeKernion JB and Morton DL: Regression following intratumor injection of BCG vaccine. J Am Med Assoc 229:688, 1974.CrossRefGoogle Scholar
  126. 126.
    DeKernion JB, Golub SH, Gupta RK, Silverstein MJ and Morton DL: Successful intralesional BCG therapy of a bladder melanoma. Cancer 36:1662–1667, 1975.PubMedCrossRefGoogle Scholar
  127. 127.
    Willis RA: The Spread of Tumors in the Human Body, p 287. CV Mosby, St. Louis, 1952.Google Scholar
  128. 128.
    Clark JH and Rowntree LG: Studies of adrenal glands in health and diease: dieases in the adrenal glands as revealed in 25,000 autopsies. Endocrinology 18:256–273, 1934.CrossRefGoogle Scholar
  129. 129.
    Glomset DA: The incidence of metastasis of malignant tumors to the adrenals. Am J Cancer 32:57–61, 1938.Google Scholar
  130. 130.
    Abeshouse BS and Goldstein AE: Metastatic malignant tumors of the kidney: a review of the literature and report of 23 cases. Urol Cutaneous Rev 45:163–186, 1941.Google Scholar
  131. 131.
    Goodall P, Spriggs AI and Wells FR: Malignant melanoma with melanosis and with pigmented monocytes and tumor cells in the blood. Br J Surg 48:549–555, 1960.CrossRefGoogle Scholar
  132. 132.
    Rosenberg JC: Melanuric Nephrosis. Arch Pathol 62:399–402, 1956.Google Scholar
  133. 133.
    Frankel RS, Richman SD, Levenson SM and Johnston GS: Renal localization of gallium-67 citrate. Radiology 114:393–397, 1975.PubMedGoogle Scholar
  134. 134.
    Lee M: Malignant melanoma: pattern of metastases. Cancer J Clin 30:137–142, 1980.CrossRefGoogle Scholar
  135. 135.
    Turner P: Melanotic sarcoma of the kidney. Proc R Soc Med 14:38–40, 1920.Google Scholar
  136. 136.
    Srivastava VK: Secondary melanoma of the ureter. Br J Urol 45:568, 1973.PubMedCrossRefGoogle Scholar
  137. 137.
    Cohen WM, Freed SZ and Husson J: Metastatic cancer to the ureter: a review of the literature and case presentations. J Urol 112:188–189, 1974.PubMedGoogle Scholar
  138. 138.
    Edson M and Hutchins KR: Metastatic melanoma of ureter. N Y State J Med 73:459–461, 1975.Google Scholar
  139. 139.
    Nakazono M, Iwata S and Kuribayashi N: Disseminated metastatic ureteral melanoma: a case report. J Urol 114:624–625, 1975.PubMedGoogle Scholar
  140. 140.
    McKenzie DJ and Bell R: Melanoma with solitary metastasis to ureter. J Urol 99:399–140, 1968.PubMedGoogle Scholar
  141. 141.
    Bergman H, Friedenberg RM and Sayegh V: New roentgenologic signs of cancer of the ureter. Am J Roentgenol 86:707–717, 1961.Google Scholar
  142. 142.
    Barnes JF and King LS: Malignant melanoma virtually limited to serous surfaces. Ill Med J 96:117, 1949.PubMedGoogle Scholar
  143. 143.
    Lowsley OS: Melanoma of the urinary tract and prostate gland. South Med J 44:487–493, 1951.PubMedCrossRefGoogle Scholar
  144. 144.
    Johnson DE, Jackson L and Ayala G: Secondary carcinoma of the testis. South Med J 64:1128–1130, 1971.PubMedCrossRefGoogle Scholar
  145. 145.
    Smith GW, Griffith DP and Pranke DW: Melanospermia: an unusual presentation of malignant melanoma. J Urol 110:314–316, 1973.PubMedGoogle Scholar
  146. 146.
    Pacquin AJ and Roland SI: Secondary carcinoma of the penis: a review of the literature and a report of 9 new cases. Cancer 9:626–632, 1956.CrossRefGoogle Scholar
  147. 147.
    Weller CV: Unusual cardiac and cerebral metastasis in melanosarcoma. J Cancer Res 7:313–327, 1922.Google Scholar
  148. 148.
    Sheil AGR: Cancer in renal allograft recipients in Australia and New Zealand. Transplant Proc 9:1133–1136, 1977.PubMedGoogle Scholar
  149. 149.
    Birkeland SA: Malignant tumours following immunosuppression in renal transplantation. Proc Eur Dial Transplant Assoc 10:429–433, 1973.PubMedGoogle Scholar
  150. 150.
    Penn I: Malignancies associated with renal transplantation. J Urol 10(suppl):57–63, 1977.CrossRefGoogle Scholar
  151. 151.
    Jeremy D, Farnsworth RH, Robertson MR, Annetts DL and Murnaghan GF: Transplantation of malignant melanoma with cadaver kidney. Transplantation 13:620–679, 1972.CrossRefGoogle Scholar
  152. 152.
    Peters MS and Stuard ID: Metastatic malignant melanoma transplanted via a renal homograft. Cancer 41:2426–2430, 1978.PubMedCrossRefGoogle Scholar
  153. 153.
    Evans DB and Calne RY: Renal transplantation in patiens with carcinoma. Br Med J 4:134–136, 1974.PubMedCrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishers, The Hague/Boston/London 1982

Authors and Affiliations

  • Sam D. GrahamJr.
  • Wayne A. ClineJr.
  • John L. Weinerth

There are no affiliations available

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