Skip to main content

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 16))

  • 243 Accesses

Abstract

The clinical expressions of pheochromocytoma are often dramatic and explosive, and are so variable that it has rightly earned the title of the ‘great mimic’ [1]. One cannot determine histologically whether a pheochromocytoma is benign or malignant. Although only 10% of these neoplasms are pathologically malignant, as evidenced by metastasis or invasion of adjacent tissue, lethal complications from the effects of excessive circulating catecholamines (epinephrine and norepinephrine) almost invariably result if the disease is not appropriately treated. All patients with manifestations even remotely suggestive of pheochromocytoma must be screened for this disease.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Decourcy JL, Decourcy CB: Pheochromocytomas and the General Practitioner. Cincinnati: Barclay Newman, 1952.

    Google Scholar 

  2. Manger WM, Gifford RW Jr: Pheochromocytoma. New York: Springer-Verlag, 1977.

    Book  Google Scholar 

  3. Winkler H, Smith AD: Pheochromocytomas and other catecholamine-producing tumors. In: Catecholamines, p. 900. Blaschko H, Muscholl E, eds. New York: Springer-Verlag, 1972.

    Google Scholar 

  4. Hermann H, Mornex R: Human Tumours Secreting Catecholamines: Clinical and Physiopathological Study. Oxford: Pergamon, 1964.

    Google Scholar 

  5. Steiner Al, Goodman AD, Powers SR: Study of a kindred with pheochromocytoma, medullary thyroid carcinoma, hyperparathyroidism and Cushing’s disease: multiple endocrine neoplasia type 2. Medicine 37: 371, 1968.

    Article  Google Scholar 

  6. Thomas JE, Rooke ED, Kvale WF. The neurologist’s experience with pheochromocytoma. A review of 100 cases. J Am Med Assoc. 197: 754, 1966.

    Article  CAS  Google Scholar 

  7. Remine WH, Chong GC, van Heerden JA, Sheps SG, Harrison EG Jr: Current management of pheochromocytoma, Ann Surg 179: 740, 1974.

    Article  PubMed  CAS  Google Scholar 

  8. Minno AM, Bennett WA, Kvale WF: Pheochromocytoma; a study of 15 cases diagnosed at autopsy. N Engl J Med 251: 959, 1954.

    Article  PubMed  CAS  Google Scholar 

  9. Aranow H Jr: Pheochromocytoma. In: Monographs in Medicine, p. 179. Bean WE, ed. Series 1. Baltimore: Williams & Wilkins, 1952.

    Google Scholar 

  10. Taubman I, Pearson OH, Anton AH: An asymptomatic catecholamine-secreting pheochromocytoma. Am J Med 57: 953, 1974.

    Article  PubMed  CAS  Google Scholar 

  11. Sjoerdsma A: Sympathoadrenal system: Pheochromocytoma. In: Cecil Loeb Textbook of Medicine. Beeson PB, McDermott W, eds. 13th edn, p. 1832. Philadelphia: W. B. Saunders, 1971.

    Google Scholar 

  12. Engelman K, Zelis R, Waldmann T, Mason DT, Sjoerdsma AM: Mechanism of orthostatic hypertension in pheochromocytoma. Circulation (suppl 6 ) 38: 72, 1968.

    Google Scholar 

  13. Keith NM, Wagener HP, Barker NW: Some different types of essential hypertension: their course and prognosis. Am J Med Sci 197: 332, 1939.

    Article  Google Scholar 

  14. Hume DM: Pheochromocytoma in the adult and in the child. Am J Surg 99: 458, 1960.

    Article  PubMed  CAS  Google Scholar 

  15. Leestma JE, Price EB Jr. Paraganglioma of the urinary bladder. Cancer 28: 1063, 1971.

    Article  PubMed  CAS  Google Scholar 

  16. Khairi MR, Dexter RN, Burzynski NJ, Johnston CC Jr: Mucosal neuroma, pheochromocytoma and medullary thyroid carcinoma: Multiple endocrine neoplasia type 3. Medicine 54: 89, 1975.

    PubMed  CAS  Google Scholar 

  17. Carney JA, Go VL, Sizemore GW, Hayles AB: Alimentary-tract ganglioneuromatosis. A major component of the syndrome of multiple neoplasia, type 2b. N Engl J Med 295: 1287, 1976.

    Article  PubMed  CAS  Google Scholar 

  18. Carney J A, Sizemore GW, Lovestedt SA. Mucosal ganglioneuromatosis, medullary thyroid carcinoma, and pheochromocytoma: Multiple endocrine neoplasia, Type 2b. Oral Surg 41: 739, 1976.

    Article  PubMed  CAS  Google Scholar 

  19. Chong GC, Beahrs OH, Sizemore GW, Woolner LH: Medullary carcinoma of the thyroid gland. Cancer 35: 695, 1975.

    Article  PubMed  CAS  Google Scholar 

  20. Robertson DM, Sizemore GW, Gordon H. Thickened corneal nerves as a manifestation of multiple endocrine neoplasia. Trans Am Acad Ophthalmol Otolaryngol 79: 772, 1975.

    Google Scholar 

  21. Brasfield RD, Das Gupta TK: Von Recklinghausen’s disease: a clinicopathological study. Ann Surg 175: 86, 1972.

    Article  PubMed  CAS  Google Scholar 

  22. DeQuattro V, Chan S: Raised plasma-catecholamines in some patients with primary hypertension. Lancet 1: 806, 1972.

    Article  PubMed  CAS  Google Scholar 

  23. Stewart BH, Bravo EL, Haaga J, Meaney TF, Tarazi R: Localization of pheochromocytoma by computed tomography. N Engl J Med 299: 460, 1978.

    Article  PubMed  CAS  Google Scholar 

  24. Wallace JM, Gill DP: Prazosin in the diagnosis and treatment of pheochromocytoma. J Am Med Assoc 240: 2752, 1978.

    Article  CAS  Google Scholar 

  25. Rosei EA, Brown J J, Lever AF. Treatment of phaeochromocytoma and of Clonidine withdrawal hypertension with labetalol. Br J Clin Pharmacol 3 (suppl 3): 809, 1976.

    PubMed  CAS  Google Scholar 

  26. El-Minawi MF, Paulino E, Cuesta M, Ceballos J: Pheochromocytoma masquerading as pre-eclamptic toxemia. Am J Obstet Gynecol 109: 389, 1971.

    PubMed  CAS  Google Scholar 

  27. Allen CT, Imrie D: Hypoglycemia as a complication of removal of a pheochromocytoma. Can Med Assoc J 116: 363, 1977.

    PubMed  CAS  Google Scholar 

  28. Wilkins GE, Schmidt N, Doll WA. Hypogycemia following excision of pheochromocytoma. Can Med Assoc J 116:367, 1977.

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1982 Martinus Nijhoff Publishers, The Hague

About this chapter

Cite this chapter

Manger, W.M., Gifford, R.W. (1982). Hypertension Secondary to Pheochromocytoma. In: Amery, A., Fagard, R., Lijnen, P., Staessen, J. (eds) Hypertensive Cardiovascular Disease: Pathophysiology and Treatment. Developments in Cardiovascular Medicine, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7476-0_36

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-7476-0_36

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-7478-4

  • Online ISBN: 978-94-009-7476-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics