Evidence for Crohn’s Disease As an Extensive Process

  • Burton I. Korelitz


Crohn’s disease as originally described was called terminal ileitis and its name was later changed to regional ileitis. Soon thereafter it was realized that granulomatous inflammation could involve the other side of the ileocecal valve, the colon. In fact, it could involve the entire colon, and this distribution was initially referred to in New York as granulomatous colitis. Soon after there was increasing emphasis on Crohn’s disease involving the anal structures. There are characteristic anal skin tabs, referred to by Dr Sohn, our colon and rectal surgeon, as “elephant ears.” When we see these, we know that they are diagnostic of Crohn’s disease. We know now that Crohn’s disease can involve the ileum, the colon, and the anal structures. We know it can manifest itself in the form of diffuse jejunoileitis. Furthermore, we have learned that it can involve the stomach alone, the stomach with the duodenum, or the duodenum alone. We know that the esophagus infrequently can be involved with Crohn’s disease. Furthermore, characteristic lesions have been found along the gingivae and on the tongue or lips, with the biopsy showing the characteristic granulomata of Crohn’s disease.


Ulcerative Colitis Pyoderma Gangrenosum Rectal Mucosa Rectal Biopsy Anal Structure 
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© John Wright PSG Inc 1982

Authors and Affiliations

  • Burton I. Korelitz

There are no affiliations available

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