Abstract
Most of the noninvasive methods heretofore used to detect cancer entail identification of the images or anatomic effects of masses of tumor cells. Although this anatomical approach has been improved by such methods as computed tomography (CAT), it probably still is not able to detect masses of tumor cells smaller than 109 cells [1,2]. Thus, there is a pressing need for better methods of detecting cancer, not only for earlier diagnosis of tumors or recurrences but also for staging and judging the response to treatment. This necessarily has stimulated a search for molecular probes; that is, tumor markers.
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Lange, P.H. (1982). Marker Proteins as a Guide in Clinical Management of Genitourinary Cancer. In: Paulson, D.F. (eds) Genitourinary Cancer 1. Cancer Treatment and Research, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7436-4_2
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