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5-Oxoprolinuria and other inborn errors related to the γ-glutamyl cycle

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Transport and Inherited Disease

Abstract

Glutathione (γ-L-glutamyl-L-cysteinyl-glycine) was isolated by Hopkins more than 50 years ago1. Initial analyses of the peptide indicated that it contained glutamic acid and cysteine, and the compound was therefore named glutathione. Its composition was revised and the correct structure was established in 19292. Since then glutathione has been identified in virtually all cells, from micro-organisms to man.

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  1. A. Larsson
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Editors and Affiliations

  1. Department of Child Life and Health, University of Edinburgh, 17, Hatton Place, Edinburgh, UK

    N. R. Belton

  2. Department of Chemical Pathology, Old Medical School, Thoresby Place, Leeds, UK

    C. Toothill

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© 1981 The Society for the Study of Inborn Errors of Metabolism

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Larsson, A. (1981). 5-Oxoprolinuria and other inborn errors related to the γ-glutamyl cycle. In: Belton, N.R., Toothill, C. (eds) Transport and Inherited Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-7316-9_14

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  • DOI: https://doi.org/10.1007/978-94-009-7316-9_14

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