Coagulopathies

  • Barbara Bain

Abstract

Haematological perturbations are almost universal in critically ill patients and can aggravate the primary disease and complicate management. Shock, infection, and renal and hepatic failure are common in critically ill and injured patients; some of their deleterious effects are mediated through the haemopoietic system, and in turn haematological dysfunction may contribute to shock, infection and failure of one or more organs. Since almost every haematological disorder is seen at some time during intensive care, it is not practicable to deal with all aspects. The coagulopathies are described in this chapter and blood transfusion in Chapter 6.Blood coagulation abnormalities and their management are of major importance in critically ill patients, who frequently suffer from abnormal bleeding, thromboembolism, or both. Depression of erythropoiesis is usual in critically ill patients but there is no effective management beyond the maintenance of adequate nutrition, which is described in Chapter 1. Megaloblastic arrest can be of vital importance and is dealt with together with other causes of thrombocytopenia. This chapter is based on my experience as the haematologist associated with a busy ICU in the Princess Alexandra Hospital, Brisbane. This unit admits 700 patients per year, and detailed coagulation studies were performed on many of these patients. Where management is controversial, I have made this clear.

Keywords

Depression Sludge Aspirin Serotonin Warfarin 

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Copyright information

© MTP Press Limited 1982

Authors and Affiliations

  • Barbara Bain

There are no affiliations available

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