Abstract
The direct incorporation of negative resistance and nonlinear damping in a mechanical model of the basilar membrane (BM) may be used to. correlate BM response data as well as the properties of stimulated and spontaneous emissions in the external auditory meatus (S. Koshigoe and A. Tubis, 1982). We have tried to remedy the ad hoc nature of this formal “black box” approach by seeking a microscopic basis for the assumed nonlinear and active BM response. Such a basis is suggested by evidence that mechanical cochlear function is strongly influenced by efferent innervation of outer hair cells (OHC) (D.C. Mountain, 1980; J.H. Siegel and D.O. Kim, 1982). We consider the chain: OHC stereocilia deflection → nonlinear change in receptor potential (A.J. Hudsneth and P.P. Corey, 1977)→induced feedback force on the BM as the primary origin of nonlinear active cochlear response. Our proposed model is qualitatively compatible with data on cochlear emissions, nonlinear cochlear response, combination-tone psychophysics, and changes in cochlear response induced by COCB stimulation or variation of the endocochlear potential.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Davis, H. (1965). A model for transducer action in the cochlea, Cold Spring Harbor Syrrip. Quant. Biol. 30, 181–189.
Flock, A., and Cheung, H.C. (1977). Actin filaments in sensory hairs of inner ear receptor cells, J. Cell. Biol. 75, 339–343.
Furst, M., and Goldstein, J.L. (1982). A cochlear nonlinear transmission-line model compatible with combination tone psychophysics, J. Acoust. Soc. Am. 72, 717–726.
Gold, T. (1948). Hearing II. The physical basis of the action of the cochlea, Proc. R. Soc. B135, 492–498.
Hall, J.L. (1974). Two-tone distortion products in a nonlinear model of the basilar membrane, J. Acoust. Soc. Am. 56, 1818–1828.
Hubbard, A.E., and Geisler, C.D. (1972). A hybrid-computer model of the cochlear partition, J. Acoust. Soc. Am. 51, 1895–1903.
Hudspeth, A.J., and Corey, D.P. (1977). Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli, Proc. Natl. Acad. Sci. U.S.A. 74, 2407–2411.
Kemp, D.T. (1978). Stimulated acoustic emissions from the human auditory system, J. Acoust. Soc. Am. 64, 1386–1391.
Khanna, S.M., and Leonard, D.G.B. (1982). Basilar membrane tuning in the cat cochlea, Science 215, 305–306.
Kim, D.O., Molnar, C.E., and Pfeiffer, R.R. (1973). A system of nonlinear differential equations modeling basilar-membrane motion, J. Acoust. Soc. Am. 54, 1517–1529.
Klinke, R., and Galley, N. (1974). Efferent innervation of vestibular and auditory receptors, Physiol. Revs. 54, 316–357.
Koshigoe, S. and Tubis, A. (1982). Unified computational model of stimulated and spontaneous acoustic emissions in the external auditory meatus, J. Acoust. Soc. Am. Suppl. 1 71, S17.
Koshigoe, S., Kwok, W., and Tubis, A. (1982). A nonlinear feedback model for mechanical response of outer-hair-cell stereocilia, J. Acoust. Soc. Am. Suppl. 1 72, S47.
Koshigoe, S., and Tubis, A. (1983). Frequency domain investigations of cochlear stability in the presence of active elements, to be published in J. Acoust. Soc. Am.
Lim, D.J. (1980). Cochlear anatomy related to cochlear mechanics. A review, J. Acoust. Soc. Am. 67, 1686–1695.
Mountain, D.C. (1980). Changes in endolymphatic potential and crossed olivocochlear bundle stimulation alter cochlear mechanics, Science 210, 71–72.
Mountain, D. C., and Hubbard, A.E. (1982). Injection of the ac current into scala media alters the sound pressure at the tympanic membrane: variations with electrical stimulus parameters, J. Acoust. Soc. Am. Suppl. 1 71, S100.
Neely, S.T. (1981). Fourth-Order Partition Dynamics for a Two-Dimensional Model of the Cochlea, doctoral dissertation, Washington University, St. Louis, Missouri.
Neely, S.T., and Kim, D.O. (1983). An active cochlear model showing sharp tuning and high sensitivity, Hearing Res. 9, 123–130.
Rhode, W.S., and Geisler, C.D. (1967). Model of the displacement between opposing points on the tectorial membrane and reticular lamina, J. Acoust. Soc. Am. 42, 185–190.
Russell, I.J., and Sellick, P.M. (1978). Intracellular studies of hair cells in the mammalian cochlea, J. Physiol. 284, 261–290.
Sellick, P.M., Patuzzi, R. and Johnstone, B.M, (1982). Measurement of basilar membrane motion in the guinea pig using the Mössbauer technique, J. Acoust. Soc. Am. 72, 131–141.
Siegel, J.H., and Kim, D.O. (1982), Efferent neural control of cochlear mechanics? Olivocochlear bundle stimulation affects cochlear biomechanical nonlinearity, Hear Res. 6, 171–182.
Tilney, L.G., DeRosier, D.J., and Mulroy, M.J. (1980). The organization of actin filaments in the stereocilia of cochlear hair cells, J. Cell. Biol. 86, 244–259.
Tilney, L.G., Egleman, E., and DeRosier, D.J., and Saunders, J.C. (1983). Actin filaments, stereocilia and hair cells of the bird cochlea. II. The packing of actin filaments in the stereocilia and in the cuticular plate and what happens to the organization when the stereocilia are bent, preprint, University of Pennsylvania.
Weiss, T.F., Mulroy, M.J., and Altmann, D.W. (1974). Intracellular responses to acoustic clicks in the inner ear of the alligator lizard, J. Acoust. Soc. Am. 55, 606–619.
Weiss, T.F. (1982). Bidirectional transduction in vertebrate hair cells: A mechanism for coupling mechanical and electrical process, Hear Res. 7, 353–360.
Wiederhold, M.L. (1967). A study of efferent inhibition of auditory nerve activity, doctoral dissertation, M.I.T., Cambridge, MA.
Wilson, J.P., and Sutton, G.J. (1981). Acoustic correlates of tonal tinnitus. In: Tinnitus, edited by D. Evered, and G. Lawrenson, (Pitman Medical, London), Ciba Found. Symp. 85.
Wit, H.P., Langevoort, J. C., and Ritsma, R.J. (1981). Freuqency spectra of cochlear acoustic emissions (Kemp-echoes), J. Acoust. Soc. Am. 70, 437–445.
Zurek, P.M. (1981). Spontaneous narrowband acoustic signals emitted by human ears, J. Acoust. Soc. Am. 69, 514–523.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Delft University Press, The Netherlands
About this paper
Cite this paper
Koshigoe, S., Tubis, A. (1983). A Non-Linear Feedback Model for Outer-Hair-Cell Stereocilia and its Implications for the Response of the Auditory Periphery. In: de Boer, E., Viergever, M.A. (eds) Mechanics of Hearing. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6911-7_15
Download citation
DOI: https://doi.org/10.1007/978-94-009-6911-7_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6913-1
Online ISBN: 978-94-009-6911-7
eBook Packages: Springer Book Archive