Abstract
We have previously suggested (1), on the basis of an analysis of the behavior of a very simple single-compartment lung model (Fig. 1) consisting of a single compliance (corresponding to the alveoli), a single resistance (corresponding to the “lumped” non-elastic resistance of the airways and lung tissue), and a single inertance (corresponding to the “lumped” inertance of the lungs and chest wall), that high-frequency ventilation might be associated with the development of considerable levels of positive end-expiratory pressure at the alveolar level despite the maintenance of normal (atmospheric) end-expiratory pressure levels at the airway.
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References
Fletcher PR, Epstein MAF, Epstein RA. Alveolar pressures during high frequency ventilation (HFV). Fed. Proc. 39: 576, 1980.
Fletcher PR, Epstein MAF, Epstein RA. A new ventilator for physiologic studies during high-frequency ventilation. Respir. Physiol. 47: 21–37.
Fletcher PR, Epstein RA. Constancy of physiological dead space during high-frequency ventilation. Respir. Physiol. 47: 39–49.
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© 1983 Martinus Nijhoff Publishers, Boston
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Fletcher, P.R. (1983). Alveolar Pressures During High Frequency Ventilation. In: Scheck, P.A., Sjöstrand, U.H., Smith, R.B. (eds) Perspectives in High Frequency Ventilation. Developments in Critical Care Medicine and Anesthesiology, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6711-3_9
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DOI: https://doi.org/10.1007/978-94-009-6711-3_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6713-7
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