Abstract
The primary use of Prostaglandin F2“ and its analogues is as luteolytic agents in cattle, sheep, goats and swine. As with any Compound, the efficacy of a particular Prostaglandin is dependent upon its inherent potency, formulation, route of administration and metabolic profile. These parameters had a marked influence on the development of fenprostalene, a new PGF2” analogue.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bourne, G. R., Mass, S. R., Phillips, P. J. et al. (1979). The disposition of the synthetic prostaglandin analogue cloprostenol (‘Estrumate’) in the rat and marmoset. Xenobiotica, 9, 623
Granstrom, E. and Hansson, G. (1976). Effect of chemical modifications on metabolic transformation of prostaglandins. In Samuelsson, B. and Paoletti, R. (eds.) Advances in Prostaglandin and Tromboxane Research. Vol. 1, p. 215. ( New York: Raven Press )
Green, K., Samuelson, B. and Margerlein, B. J. (1976). Decreased rate of metabolism induced by a shift in the double bond in prostaglandin ¥ia from the A5 to the A4 position. Eur. J. Biochem., 62, 527
McDonald, L. E., McNutt, S. H. and Nichols, R. E. (1953). On the essentiality of the bovine corpus luteum of pregnancy. Am. J. Vet. Res., 14, 539
Singh, L. P., Sadiku, A. and Verma, O. P. (1979). Prostaglandin F2x-induced response of the bovine ovary, oviduct (uterine tube), and uterus. J. Am. Vet. Res., 40, 1789–91
Speroff, L. and Ramwell, P. N. (1970). Prostaglandins in reproductive physiology. Am. J. Obstet. Gynecol., 107, 1110–30
Upjohn Veterinary Report no 12. Abortion Induction in Feedlot Heifers. (Kalamazoo, Michigan, USA: The Upjohn Company)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 MTP Press Limited
About this chapter
Cite this chapter
Herschler, R.C., Kent, J.S., Tomlinson, R.V. (1983). New prostaglandins: present studies and future. In: Ruckebusch, Y., Toutain, PL., Koritz, G.D. (eds) Veterinary Pharmacology and Toxicology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6604-8_20
Download citation
DOI: https://doi.org/10.1007/978-94-009-6604-8_20
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6606-2
Online ISBN: 978-94-009-6604-8
eBook Packages: Springer Book Archive