Abstract
L-thryoxine (18.9 nmol) injected into chicken eggs accelerates the development of lung function, the decrease of liver metabolites, and the onset of hatching. A low dose of thiourea (13.11 μmol) exerts an opposite effect on these parameters. Under the influence of a high dose of thiourea (32.8 μmol) hatching, lung ventilation and the normal increase of somatic activity are suppressed. Furthermore, the increase of O2 consumption and the changes of O2 and CO2 concentration in the air cell occurring normally towards the end of incubation are also prevented under these conditions. The results suggest a decisive role for pulmonary gas exchange in initiating hatching.
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References
Balaban, M. and Hill, J. (1971). Effects of thyroxine level and temperature manipulations upon the hatching of chick embryo (Gallus domestic - us). Dee. Ps, vchobiol. 4: 17–35.
Beyer, R.F. (1952). The effect of thyroxine upon the general metabolism of the intact chick embryo. Endocrinology 50: 497–503.
Dauber, J., Pluss, W., Stenmark, K., Weil, J. and Voelkel, N. (1983). Leukotrienes in thiourea-induced lung injury edema. Ann. Rev. Resp. Dis. 127: 304.
Freeman, B.M. (1965). The importance of glycogen at the termination of the embryonic existence of Gallus domesticus. Comp. Biochem. Phvsiol. 14: 217–722.
Freeman, B.M. and Manning, A.C. (1971). Glycogenolysis and lipolysis in Gallus domesticity during the perinatal period. Comp. Gen. Pharmac. 2: 198 204.
Greenberg, A.H., Najjar, S. and Blizzard. R.M. (1974). Effects of thyroid hormone on growth differentiation and development. In: handbook of Physiology, Vol. III. Monte A. Green and D.H. Soleman, eds., American Physiological Society, Washington. D.C., pp. 373–390.
Hollinger, M.A., Girt Shri, N., Hwang. F. and Budd, E. (1974). Effect of thiourea on rat lung protein Synthesis. Res. Commun. Chem. Pathol. Pharmacy 8 (2): 319–326.
Keppler, D. and Decker, A. K. (1970). Glvkogen. ln:Methoden der enzymatischen Analyse. H.U. Bergmeyer, ed., pp. 1089–1093.
Kugler, W., Wittmann. J. and Petry. H. (1952). Kontinuierliche Registrierung von Motilität und Lungenatmung in der Pränatalen Phase des Kilkens. /61. Vet. Med. A 29: 395–402.
Lamprecht, W. and Trautschold, D. (1970). ATP-Bestimmung. In: Methoden der enzymatischen Analyse, H.U. Bergmeyer. ed., pp. 2024–2033.
Lardy, H.A. (1954). Effect of thyroid hormone on enzyme systems. Brookhaven Symp. Biol. 7: 90–97.
Martius, C. and Hess, B. (1951). The mode of action of thyroxine. Arch. Biochem. Biophys. 33: 468–487.
Romanoff, A.L. and Lauffer, H. (1956). The effect of injected thiourea on the development of some organs of the chicken embryo. Endocrinology 56: 611–619.
Scholander, P.F. and Edwards. G.A. (1942). Micro-respiration apparatus. Rev. Sci. Instru. 13: 292–295.
Sterling, K., Brenner, M.A. and Sakurado. T. (1980). Rapid effect of triiodo-thyronine on the mitochondria) pathway in rat liver in vivo. Science 210: 340–343.
Tazawa, T., Ar, A., Rahn, H. and Piiper. J. (1980). Repetitive and simultaneous sampling from the air cell and blood vessels in the chick embryo. Respir. Phvsiol. 39: 265–272.
Visschedijk, A.H.J. (1968). The air space and embryonic respiration. Br. Pouls. Sci. 9: 173–210. Wangensteen, O.D. and Rahn, H. (1970171). Respiratory gas exchange by the avian embryo. Respir. Phys. 11: 31–45.
Wangensteen. O.D.. Wilson. D. and Rahn, H. (197(1/71). Diffusion of gases across the shell of the hen’s egg. Respir. Physiol. 11: 16–30.
Wittmann, J. and Weiss. A. (1981). Studies on the metabolism of glycogen and adenine nucleotides in embryonic chick liver at the end of incubation. Comp. Biochem. Physiol. 69C: 1–6.
Wittmann. J., Kugler. W. and Petry, H. (1983). Motility pattern and lung respiration of embryonic chicks under the influence of l,-thyroxine and thiourea. Comp. Biochem. Physiol. 75A: 379–384.
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© 1984 Dr W. Junk Publishers, Dordrecht
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Wittmann, J., Kugler, W., Kolb, H. (1984). Influence of L-thyroxine and thiourea on metabolism and lung respiration in embryonic chicks. In: Seymour, R.S. (eds) Respiration and metabolism of embryonic vertebrates. Perspectives in vertebrate science, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6536-2_22
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DOI: https://doi.org/10.1007/978-94-009-6536-2_22
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