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Recent Progress in LC/MS

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Analysis of Organic Micropollutants in Water

Summary

Recent developments in the coupling of a liquid chromatograph with a mass spectrometer are reviewed with particular emphasis on commercially available systems. A new interface of the moving belt type enables molecular weight to be obtained by electron impact or chemical ionization from a wider range of compounds than was previously possible with interfaces of this type. Use of fast atom bombardment mass spectrometry with a moving belt interfaces shows promise for further extension of the compounds amenable to LC/MS study. Improvements in the methods of feeding the sample onto the belt, by use of a nebulizer or microbore liquid chromatography have resulted in improved. sample detection limits and easier handling of mobile phases with a high water content. The range of compounds amenable to study by interfaces of the direct liquid introduction type have also been extended. Thermospray ionization systems show considerable potential for handling more difficult molecules and in providing improved detection limits. Advances in the use of atmospheric pressure ionization in this area are also described. Finally the utility of LC/MS in the environmental area is reviewed and analysis of testwell samples from a landfill site using the technique is described.

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Author information

Authors and Affiliations

  1. Department of Chemistry, University College Cardiff, UK

    D. E. Games & M. A. McDowall

  2. Ontario Ministry of the Environment, Canada

    M. Glenys Foster & O. Meresz

Authors
  1. D. E. Games
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  2. M. A. McDowall
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  3. M. Glenys Foster
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  4. O. Meresz
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Editor information

Editors and Affiliations

  1. Commission of the European Communities, Brussels, Belgium

    G. Angeletti (Directorate-General for Science) (Directorate-General for Science)

  2. Central Institute for Industrial Research, Oslo, Norway

    A. Bjørseth

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© 1984 ECSC, EEC, EAEC, Brussels and Luxembourg

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Games, D.E., McDowall, M.A., Foster, M.G., Meresz, O. (1984). Recent Progress in LC/MS. In: Angeletti, G., Bjørseth, A. (eds) Analysis of Organic Micropollutants in Water. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6345-0_8

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  • DOI: https://doi.org/10.1007/978-94-009-6345-0_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-6347-4

  • Online ISBN: 978-94-009-6345-0

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