Abstract
Unlike the frequently used physico-chemical methods like NMR or CD or IR spectroscopy e.g. calorimetry does not center directly on the object under research but on the object and its environment, since nearly all chemical and biochemical processes are combined with a production or consumption of heat, and therefore with a flow of heat between the object and its surrounding.
It is beyond the scope of this review to describe the different instruments and methods in detail. We will rather try to give an impresion of the wide area of applications of calorimetry in life sciences as an analytical tool. Concerning instrumentation we will only briefly describe calorimeters which are commerciablely available and will meet certain demands for research work. Most experimental work presented here deals with model compounds. There are forthcoming an increasing number of papers on calorimetry of microorganisms and the occasional attempt to follow the generation of heat in compete biological objects. This last field of application is the most recent and the examples serve to show how far the applicability of calorimetry in life sciences can reach today.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Clausius,R.: 1850, Annalen der Physik 155, pp.368ff.
Ackermann, Th. and Ruterjans, H.: 1964, Z. Physik. Chemie 41, pp. 116ff.
Ising, E.: 1925, Z. Physik 31, pp. 253ff.
Sturtevant, J.M.: 1969, Proc. 1st. Int. Conf. Calorimetry Warsaw.
Privalov, P.L., Plotnikov, V.V. and Filimonov, V.V.: 1975, J. Chem. Thermodynamics 7, pp. 4Iff.
Diener, T.O.: 1974, Ann. Rev. Microbiol. 28, pp 23–39.
Marmur, J. and Doty, P.: 1962, J. Mol. Biol. 5, pp. 109ff.
Steiner, R.F. and Beers, R.F.: 1961, “Polynucleotides”, pp. 21 - 63, Elsevier Publ. Comp., Amsterdam.
Watson, J.D.: 1977, “Molecular Biology of the Gene”, pp. 73ff, W.A.Benjamin Inc., Menlo Park, Cal..
Chargaff, E.: 1950, Experimentia (Basel) 6, pp. 20Iff.
Watson, J.D. and Crick, F.H.: 1953, Nature 171, pp. 737ff.
Klump, H. and Ackermann, Th.: 1971, Biopolymers 10, pp. 513ff.
Van Holde, K.E., Brahms, J. and Michelson, A.M.: 1965, J. Mol. Biol. 12, pp. 726ff.
Gruenwedel, D.W.: 1974, Biochem. Biophys. Acta 340, pp. 16 - 30.
Schildkraut, C.L., Marmur, J. and Doty, P.: 1962, J. Mol. Biol. 4, pp. 430ff.
Klump, H.: 1968, Thesis, Mlinster.
Krakauer, H. and Sturtevant, J.M.: 1968, Biopolymers 6, pp. 491ff.
Breslauer, K.J. and Sturtevant, J.M.: 1975, J. Mol. Biol. 99, pp. 552ff.
Privalov, P.L.: 1974, FEBS Letters 40, pp. 140ff.
Langowski, J., Henco, K., Riesner, D. and Sanger, H.L.: 1978, Nucl. Acid Res. 5, pp. 1589ff.
Gross, H.J., Domday, H. et al.: 1978, Nature 273, pp. 203 - 208.
Klump, H., Riesner, D. and Sanger, H.L.: 1978, Nucl. Acid Res. 5, pp. 1581ff.
Klump, H. and Breslauer, K.J.: to be published in Biopolymers.
Weischet, W., Tatchell, K., Van Holde, K.E. and Klump, H.: 1978, Nucl. Acid Res. 5, pp. 139 - 151.
Olins, D.E. and Olins, A.L.: 1974, Science 183, pp. 330ff.
Klump, H. and Hlitig, H.: 1980, Ber. Bunsenges. Physik. Chemie 84, pp. 250 - 253.
Klump, H., Schmid, E.D. and Moschallski, M.: 1982, Vlllth. Intern. Conf. on Raman Spectroscopy, Bordeaux.
Klump, H., Gaber, B.P., Peticolas, W.L. and Yager, P.: 1981, Thermochim. Acta 48, pp. 361 - 366.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 D. Reidel Publishing Company
About this chapter
Cite this chapter
Klump, H. (1984). Application of Calorimetry to the Life Sciences. In: Ribeiro da Silva, M.A.V. (eds) Thermochemistry and Its Applications to Chemical and Biochemical Systems. NATO ASI Series, vol 119. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6312-2_24
Download citation
DOI: https://doi.org/10.1007/978-94-009-6312-2_24
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6314-6
Online ISBN: 978-94-009-6312-2
eBook Packages: Springer Book Archive