Abstract
Swine dysentery, an infectious disease of pigs, in which the lesions are confined to the large bowel, provides an interesting example of the use of animal models in the study of an animal disease. The most important model is the natural host itself, and swine dysentery has been reproduced experimentally in conventional pigs. In addition, other animal models of the disease have been developed, namely the gnotobiotic pig (1), the guinea pig (2) and the CFI mouse (3). The ligated colonic loop in pigs (4), though not strictly an animal model, can be regarded as an in vivo model.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Meyer RC, Simon J and Byerly CS. (1975). The etiology of swine dysentery. III. The role of selected Gram-negative obligate anaerobes. Veterinary Pathology 12, 46–56.
Joens LA, Songer JG, Harris DL and Glock RD. (1978). Experimental infection with Treponema hyodysenteriae in guinea pigs. Infection and Immunity 22, 132–135.
Joens LA and Glock RD. (1979). Experimental infection in mice with Treponema hyodysenteriae. Infection and Immunity 25, 757–760.
Whipp SC, Harris DL, Kinyon JM, Songer JG and Glock RD. (1978). Enteropathogenicity testing of Treponema hyodysenteriae in ligated colonic loops of swine. American Journal Veterinary Research 39, 1293–1296.
Whiting RA, Doyle LP and Spray RS. 1921). Swine dysentery. Purdue University Agricultural Experimental Station Bulletin 257, 1–15.
Taylor DJ and Alexander TJL. (1971). The production of dysentery in swine by feeding cultures containing a spirochaete. British Veterinary Journal 127, 58–61.
Harris DL, Glock RD, Christensen CR and Kinyon JM. (1972). Swine dysentery, 1. Inoculation of pigs with Treponema hyodysenteriae (new species) and reproduction of the disease. Veterinary Medicine and Small Animal Clinician 67, 61–64.
Alexander TJL and Wellstead PD. (1974). Bacteria isolated from scrapings of the mucosal wall of the colon. Proceedings 3rd Congress International Pig Veterinary Society, Abstract D 5.
Alexander TJL, Wellstead PD and Hudson MJ. (1976). Studies of bacteria other than Treponema hyodysenteriae which may contribute to the lesion of swine dysentery. Proceedings of the 4th Congress International Pig Veterinary Society, Abstract L1.
Robinson IM, Allison MJ and Whipp SC. (1982). Characterisation of bacteria adherent to colonic epithelia of pigs with dysentery. Proceedings Annual Meeting American Society for Microbiology, Abstract 158.
Harris DL, Alexander TJL, Whipp SC, Robinson IM, Glock RD and Matthews PJ. (1978). Swine dysentery: Studies of gnotobiotic pigs inoculated with Treponema hyodysenteriae, Bacteroides vulgatus and Fusobacterium necrophorum. Journal of the American Veterinary Medical Association 172, 468–471.
Lysons RJ, Hall GA, Alexander TJL, Bew J and Blanc AP. (1978). Aetiological agents and pathogenesis of swine dysentery. Proceedings 8th Congress International Pig Veterinary Society, Abstract M1.
Whipp SC, Robinson IM, Harris DL, Glock RD and Matthews PJ. (1980). Inoculation of gnotobiotic pigs with Treponema hyodysenteriae in the presence and absence of selected anaerobes. Proceedings 6th International Congress International Pig Veterinary Society p230.
Whipp SC, Pohlenz JFL, Harris DL, Robinson IM, Glock RD, Kunkle R. (1982). Pathogenicity of Treponema hyodysenteriae in uncontaminated gnotobiotic pigs. Proceedings 7th Congress International Pig Veterinary Society p31.
Pohlenz JFL, Lysons RJ, Whipp SC, Harris DL and Fargerland JA. (1983). Morphology of the intestinal mucosa in gnotobiotic pigs experimentally infected with a pathogenic and an apathogenic strain of Treponema hyodysenteriae. Proceedings 3rd International Symposium of Veterinary Laboratory Diagnosticians, P553–558.
Lemcke RM, Bew J, Burrows MR and Lysons RJ. (1979). The growth of Treponema hyodysenteriae and other porcine intestinal spirochaetes in a liquid medium. Research in Veterinary Science 26, 315–319.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Martinus Nijhoff Publishers, Dordrecht
About this chapter
Cite this chapter
Lysons, R.J. (1984). Enterocolitis of Pigs. In: Hill, M.J. (eds) Models of Anaerobic Infection. New Perspectives in Clinical Microbiology, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6054-1_6
Download citation
DOI: https://doi.org/10.1007/978-94-009-6054-1_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-6056-5
Online ISBN: 978-94-009-6054-1
eBook Packages: Springer Book Archive