Detection and Identification of Papillomaviruses in Benign and Malignant Tumours of Cattle
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Papillomavirus has been isolated from different types of tumours in British cattle. By using restriction enzyme analysis and molecular hybridization six different types of bovine papillomavirus (BPV-1 to 6) have been identified and characterized. Each virus type has been found associated with a particular lesion and their evolutionary relationship has been established. It is concluded that BPVs fall into two subgroups: subgroup A viruses cause fibropapillomas and subgroup B viruses cause true epithelial papillomas. The members of each subgroup are related to one another, but not to the members of the other subgroup. In addition, the presence of viral genomes has been detected by molecular hybridization in tumours non-productive for mature virus progeny.
KeywordsViral Genome Alimentary Tract Alimentary Canal Soli Sail Nitrocellulose Paper
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