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Capture Assays for the Detection of Virus-Specific IgM Antibody

  • Richard S. Tedder
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Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 29)

Abstract

Class-specific antibody capture assays have been developed for a number of human virus infections, in particular for the detection of IgM antibody. These assays, MACRIA’s, have a number of advantages over the more conventional indirect solid-phase immunoassays. They are sensitive and unaffected by rheumatoid factor and particularly suited to detecting specific IgM in sera from neonates. While veterinarians will need to develop species-specific anti-μFc antisera, the compensation is that once this is done, the pair of appropriately balanced reagents, virus antigen and its labelled antibody, will be suitable to diagnose recent infection by a given virus in any animal species.

Keywords

Rheumatoid Factor Capture Assay Rubella Virus Infection Single Dilution Indirect Immunoassay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1984

Authors and Affiliations

  • Richard S. Tedder
    • 1
  1. 1.Department of Virology (Microbiology), School of PathologyMiddlesex Hospital Medical SchoolLondonUK

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