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Diagnostic use of CNS Antibodies

  • Kurt Danner
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Part of the Current Topics in Veterinary Medicine and Animal Science book series (CTVM, volume 29)

Abstract

Antibodies appear in the CNS either by leakage from serum through an impaired blood-CNS barrier or after local production during certain infections of the CNS, such as distemper in the dog or measles/SSPE in man. Locally produced CNS antibodies are different from serum antibodies but can be demonstrated by the same techniques. They may be taken for routine diagnosis especially when the aetiological agent is difficult to identify. Our own experiences with Borna disease in horses, sheep and rabbits are presented, since its diagnosis intra vitam and post mortem is routinely based upon demonstration of CNS antibodies. It is suggested that the method might be applicable to other viral infections of the CNS.

Keywords

Multiple Sclerosis Rabies Virus Canine Distemper Virus Japanese Encephalitis Virus Subacute Sclerosing Panencephalitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1984

Authors and Affiliations

  • Kurt Danner
    • 1
  1. 1.Institut fur Hygiene und Infektionskrankheiten der TiereJustus Liebig-UniversitatGiessenFederal Republic of Germany

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