Abstract
Recently, several investigators have advocated the use of the Indium radionuclide 111Indium (used as 111Indium-oxinate) for labelling of lymphocytes, to study their homing and recirculation (1–4). In fact, this method has already been applied in man (5–9). However, data on the functional properties of 111In-labelled human lymphocytes are sparse (10). The present study was undertaken to measure the spontaneous release of 111In from labelled cells and the effect of 111In labelling on the proliferative capacity of human peripheral blood lymphocytes. As a parameter for radiation-induced cell damage, the chromosomal pattern of the cells was studied.
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© 1984 Martinus Nijhoff Publishers, The Hague
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Ten Berge, R.J.M., Natarajan, A.T., Yong, S.L., Hardeman, M.R., Van Royen, E.A., Schellekens, P.T.A. (1984). Labelling of Human Lymphocytes with 111In-Oxinate. In: Hardeman, M.R., Najean, Y. (eds) Blood cells in nuclear medicine, part I. Developments in Nuclear Medicine, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6027-5_33
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DOI: https://doi.org/10.1007/978-94-009-6027-5_33
Publisher Name: Springer, Dordrecht
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