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Current Concepts and Perspectives in Epidural Anaesthesia

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Current Concepts in Regional Anaesthesia

Part of the book series: Developments in Critical Care Medicine and Anaesthesiology ((DCCA,volume 7))

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Abstract

You cannot make something work until you understand how it works. Epidural anesthesia has been with us since the turn of the century, but it is only in the last twenty-five years or so that the tools have become available to help us understand and exploit its mechanisms of action. We have come a long way in that time, and the most rapid advances have taken place in the past 5 years.

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References

  1. Corning J L (1885) Spinal anaesthesia and local medication of the cord. N Y Med J 42:483.

    Google Scholar 

  2. Dogliotti A M (1931) Anesthesia. S D Debour, Chicago p 537.

    Google Scholar 

  3. Dawkins C J M (1945) Extradural spinal block. Proc Roy Soc Med 38:299.

    Google Scholar 

  4. Bromage P R, Joyal A C and Binney J C (1963) Local anesthetic drugs: Penetration from the spinal extradural space into the neuraxis. Science 140:392–393.

    Article  PubMed  CAS  Google Scholar 

  5. Moore R A, Bullingham R E, McQuay H J, Hand C W, Aspel J B, Allen M C and Thomas D (1982) Dural permeability to narcotics: In vitro determination and application to extradural administration. Brit J Anaes 54:1117–1128.

    Article  CAS  Google Scholar 

  6. Cousins M J, Mather C, Glynn C J (1979) Selective spinal anesthesia. Lancet 1:1141–1142.

    Article  PubMed  CAS  Google Scholar 

  7. Nordberg G, Hedner T, Mellstrand T and Dahlstrom B (1983) Pharmacokinetic aspects of epidural morphine analgesia. Anesthesiology 58:545–551.

    Article  PubMed  CAS  Google Scholar 

  8. Schulte-Steinberg O and Rahlfs V W (1970) Caudal anaesthesia in children and spread of 1 per cent lignocaine: A statistical study. Brit J Anaesth 42:1093–1099.

    Article  PubMed  CAS  Google Scholar 

  9. Tucker G T, and Mather L E (1980) Absorption and disposition of local anesthetics: Pharmacokenetics. in Neural Blockade in Clinical Management of Pain. J B Lippincot Company, Phil. and Toronto pp 45–85.

    Google Scholar 

  10. Yaksh T L and Ramana Reddy S V (1981) Studies in the Primate on the analgetic effects associated with intrathecal actions of opiates, a-Adrenergic agonists and baclofen. Anesthesiology 54:451–467.

    Article  PubMed  CAS  Google Scholar 

  11. Bromage P R, Camporesi E M, Durant P A and Nielsen C H (1983) Influence of Epinephrine as as adjuvant to epidural morphine. Anesthesiology 58:257–262.

    Article  PubMed  CAS  Google Scholar 

  12. Bromage P R, O’Beirn P and Dunford L A (1974b) Etidocaine: A clinical evaluation for regional analgesia in surgery. Canad Anaesth Soc J 21:523–534.

    Article  PubMed  CAS  Google Scholar 

  13. Bromage P R (1978) Table 12–3 Placental transfer of local anesthetics in lumbar epidural and caudal blockade during labor. in Epidural Analgesia. W B Saunders Company, Phil., London and Toronto pp 536–537.

    Google Scholar 

  14. Bromage P R, Camporesi E and Leslie J (1980) Epidural narcotics in volunteers: sensitivity to pain and to carbon dioxide. Pain 9:145–160.

    Article  PubMed  CAS  Google Scholar 

  15. Bromage P R, Shibata H R and Willoughby H W (1971) Influence of prolonged epidural blockade on blood sugar and Cortisol responses to operations upon the upper part of abdomen and the thorax. Surg Gynecol Obstet 132:1051–1056.

    PubMed  CAS  Google Scholar 

  16. Brandt M R, Fernandes A, Mordhurst R et al (1978) Epidural analgesia improves postoperative nitrogen balance. Brit Med J i:1106–1108.

    Article  Google Scholar 

  17. Bromage P R, Camporesi E M, Chestnut D (1980) Epidural narcotics for postoperative analgesia. Anesth & Analg 59:473–480.

    Article  CAS  Google Scholar 

  18. Calvillo O, Henry J L, Neuman R S (1974) Effects of morphine and naloxone on dorsal horn neurones in the cat. Can J Physiol Pharmacol 52:1207–1211.

    Article  PubMed  CAS  Google Scholar 

  19. Wang J L, Nauss L A and Thomas J E (1979) Pain relief by intrathecally applied morphine in man. Anesthesiology 50:149–151.

    Article  PubMed  CAS  Google Scholar 

  20. Behar M, Olshwang D, Magora F and Davidson J T (1979) Epidural morphine in treatment of pain. Lancet 1:527–528.

    Article  PubMed  CAS  Google Scholar 

  21. Bromage P R, Camporesi E M, Durant P A C and Nielsen C H (1982) Rostral spread of epidural morphine. Anesthesiology 56:431–436.

    Article  PubMed  CAS  Google Scholar 

  22. Bromage P R, Camporesi E M, Durant P A and Nielsen C H (1983) Influence of epinephrine as an adjuvant to epidural morphine. Anesthesiology 58:257–262.

    Article  PubMed  CAS  Google Scholar 

  23. Bromage P R, Camporesi E M, Durant P A C and Nielsen C H (1982) Nonrespiratory side effects of epidural morphine. Anesth & Anaig 61:490–495.

    CAS  Google Scholar 

  24. Rawal N, Mollefors K, Axelsson K, Lingardh G and Widman B (1983) An experimental study of urodynamic effects of epidural morphine and of naloxone reversal. Anesth & Analg 62:641–647.

    Article  CAS  Google Scholar 

  25. Camporesi E M, Nielsen C H, Bromage P R, Durant, P A C (1983) Ventilatory CO2 sensitivity after intravenous and epidural morphine in volunteers. Anesth & Analg 62:633–640.

    Article  CAS  Google Scholar 

  26. Cousins M J and Wright C J (1971) Graft, muscle, skin blood flow after epidural block in vascular surgical procedures. Surg Gynecol Obstet 133:59–64.

    PubMed  CAS  Google Scholar 

  27. Justins D M, Houlton P G, Reynolds F (1982) Controlled trial of extradural fentanyl in labour. Brit J Anaesth 54:409–414.

    Article  PubMed  CAS  Google Scholar 

  28. Doblar D D, Muldoon S M, Albrecht P H, Baskoff J, Watson R I (1981) Epidural morphine following epidural local anesthesia effect on ventilatory and airway occlusion pressure response to CO2. Anesthesiology 66:423–428.

    Article  Google Scholar 

  29. Kafer E R, Brown J T, Scott D, Findlay J W A, Butz R F, Teeple E and Ghia J N (1983) Biphasic Depression of Ventilatory Responses to CO2 Following Epidural Morphine. Anesthesiology 58:418–427.

    Article  PubMed  CAS  Google Scholar 

  30. Knill R L, Clement J L, Thompson W R (1981) Epidural morphin causes delayed and prolonged ventilatory depression. Canad Anaesth Soc J 28:537–543.

    Article  PubMed  CAS  Google Scholar 

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© 1984 Martinus Nijhoff Publishers, The Hague

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Bromage, P.R. (1984). Current Concepts and Perspectives in Epidural Anaesthesia. In: Van Kleef, J.W., Burm, A.G.L., Spierdijk, J. (eds) Current Concepts in Regional Anaesthesia. Developments in Critical Care Medicine and Anaesthesiology, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6015-2_17

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  • DOI: https://doi.org/10.1007/978-94-009-6015-2_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-6017-6

  • Online ISBN: 978-94-009-6015-2

  • eBook Packages: Springer Book Archive

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