Advertisement

Significance of Electrocardiographic Changes in Acute Transient Myocardial Ischemia

  • A. Biagini
  • C. Carpeggiani
  • M. G. Mazzei
  • Testa R. 
  • A. L’Abbate
Chapter
  • 29 Downloads
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 37)

Abstract

The significance of different electrocardiographic alterations in relation to myocardial ischemia, derives normally from studies performed in animals, where it is possible, during the experimental setting, to correlate directly the entity of ischemia with the observed electrocardiographic variations. The information obtained in this way has been used in the clinical setting and also has been compared with the data obtained from the follow up of these patients and eventually from autoptic examinations. Moreover in recent years techniques have became available which allow to study more accurately and precisely, in patients and in animals, the distribution of myocardial blood flow, the myocardial contractility and the anatomy of the coronary vascular bed. More recently the possibility to monitorize the electrocardiogram of ambulatory patients for long periods of time has given rise to new questions that in part are still open to discussion. Object of this report will be to review the data in the literature on the correlation of the different electrocardiographic changes to acute transient myocardial ischemia, in patients and animals with particular reference to the data obtained in ambulatory patients.

Keywords

Myocardial Ischemia Myocardial Blood Flow Holter Monitoring Electrocardiographic Change Ambulatory Monitoring 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bertrand, M.E., Laisue, C., Lefebvre, J.M., Carre, A., Warembourg, H. and Leikieffre J. 1977. Le spasme des arteres coronaires. Arch. Mal. Coeur., 70, 1233.PubMedGoogle Scholar
  2. Biagini, A., L’Abbate, A., Mazzei, M.G., Carpeggiani, C., Testa, R., Antonelli, R., Michelassi, C., Benassi, A. and Maseri, A. 1980. Inaffidabilità del monitoraggio elettrocardiografico in Unità di Cura Coronarica per il riconoscimento di episodi di ischemia miocardica. Giorn. It. Cardiol., 10, 1449.Google Scholar
  3. Biagini, A., Mazzei, M.G., Carpeggiani, C., Testa, R., Antonelli, R., Michelassi, C., L’Abbate, A. and Maseri A. 1982. Vasospastic ischemic mechanism of frequent asymptomatic transient ST-T changes during continuous electrocardiographic monitoring in selected unstable angina patients. Am. Heart. J., 103, 13.PubMedCrossRefGoogle Scholar
  4. Biagini, A., Michelassi, C., Mazzei, M.G., Carpeggiani, C., Testa, R., Benassi, A., Varanini, C.M., Riva, A., Marchesi, C. and L’Abbate, A., 1982. Electrocardiographic changes during Prinzmetal angina: QRS versus ST segment variation. IEEE Computer Society Press, Silver Spring, Maryland, p. 237.Google Scholar
  5. Biagini, A., Testa, R., Carpeggiani, C., Mazzei, M.G., Emdin, M., Michelassi, C. and L’Abbate, A. 1982. Contributo dell’elettrocardiografia dinamica alla conoscenza della cardiopatia ischemica silente. In: “La Cardiopatia Ischemica Silente”, Prati P.L., edr. p. 81.Google Scholar
  6. Bragg-Remschel, D.A., Anderson, C.H. and Winkle, R.A. 1982. Frequency response characteristics of ambulatory ECG monitoring system and their implications for ST segment analysis. Am. Heart J., 103: 20.PubMedCrossRefGoogle Scholar
  7. Buckberg, G.D., Fixler, D.E., Archie, J.P. and Hoffman, J.I.E. 1972. Experimental subendocardial ischemia in dogs with normal coronary arteries. Circ. Res., 30, 67.PubMedGoogle Scholar
  8. Chierchia, S., Brunelli C., Simonetti, I., Lazzari, M. and Maseri A. 1980. Sequence of events in angina at rest: primary reduction in coronary flow. Circulation, 61, 759.PubMedGoogle Scholar
  9. Chierchia, S., Lazzari, M., Simonetti, I. and Maseri A. 1980 Hemodynamic monitoring in angina at rest. Herz, 5, 188.Google Scholar
  10. Distante, A., Rovai, D., Picano, E., Moscarelli, E., Palombo, C., Morales, M.A., Michelassi, C. and L’Abbate, A. 1983. Transient changes in left ventricular mechanics during attacks of Prinzmetl angina: an M-Mode echocardiographic study. Am. Heart J. (in press).Google Scholar
  11. Geary, G.G., Smith, G.T., Mc Namara, J.J. 1981. Defining the anatomic perfusion bed of an occluded coronary artery and the region at risk to infarction. A comparative study in the baboon, pig and dog. Am. J. Cardiol., 47, 1240.PubMedCrossRefGoogle Scholar
  12. L’Abbate, A., Marzilli, M., Ballestra A.M., Camici, P., Trivella, M.G., Pelosi, G. and Klassen, G.A. 1980. Opposite transmural gradients of coronary resistance and extravascular pressure in the working dog’s heart. Cardiov. Res., 14, 21.CrossRefGoogle Scholar
  13. Maseri, A., L’Abbate, A., Pesola, A., Ballestra, A.M., Marzilli, M., Severi, S., Maltinti, G., De Nes, M., Parodi, O. and Biagini A. 1977. Coronary vasospasm in angina pectoris. Lancet, 1, 713.PubMedCrossRefGoogle Scholar
  14. Maseri, A., Mimmo, R., Chierchia, S., Marchesi, C., Pesola, A. and L’Abbate, A. 1975. Coronary artery spasm as a cause of acute myocardial ischemia in man. Chest, 68, 625.CrossRefGoogle Scholar
  15. Maseri, A., Parodi, O., Severi S. and Pesola, A. 1976. Transient transmural reduction of myocardial blood flow demonstrated by thallium-201 scintigraphy as a cause of variant angina. Circulation, 56, 280.Google Scholar
  16. Matsuguch, T., Koiwaya, Y., Nakasaki, O., Orita, Y., and Nakamura, M. 1982. Negative U wave and peaked T wave without ST changes during spontaneous and ergonovine-induced vasospastic angina. Am. J. Heart, 6, 918.CrossRefGoogle Scholar
  17. Parodi, O., Marzullo, P., Galli, M., Bencivelli, W., Agostini, F. and L’Abbate, A. 1982. Different pattern of contractility and perfusion in resting angina with ST segment elevation and depression. Am. J. Cardiol., 49, 1016.CrossRefGoogle Scholar
  18. Parodi, O., Uthurralt, N., Severi, S., Bencivelli W., Michelassi, C. and Maseri, A. 1981. Transient reduction of regional myocardial perfusion during angina at rest with ST segment depression or normalization of negative T waves. Circulation, 63, 1238.PubMedCrossRefGoogle Scholar
  19. Stern, S., Tzivoni, D. and Stern, Z. 1975. Diagnostic accuracy of ambulatory ECG monitoring in ischemic heart disease. Circulation, 52, 1045.PubMedGoogle Scholar

Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1984

Authors and Affiliations

  • A. Biagini
    • 1
  • C. Carpeggiani
    • 1
  • M. G. Mazzei
    • 1
  • Testa R. 
    • 1
  • A. L’Abbate
    • 1
  1. 1.C.N.R. Institute of Clinical Physiology and Istituto Patologia MedicaUniversity of PisaPisaItaly

Personalised recommendations