Abstract
Micro-organisms of many genera and species have been found associating closely with epithelial surfaces of mucous membranes in various areas of the bodies of animals of numerous types including man (Gibbons and Van Houte, 1975; Jones, 1977; Savage, 1977a). Some of these microbial types are known to adhere to substances on or in the mucosal epithelia with which they associate. In this chapter, I discuss some such micro-organisms confining the discussion to micro-organisms of the ‘normal flora’ (see definition below) found in the gastro-intestinal tracts of man, some other mammals and certain birds. Micro-organisms of the normal flora are known to adhere to mucosal surfaces in the buccal cavity of humans (Gibbons and Van Houte, 1975) and undoubtedly adhere to such surfaces in the upper respiratory (Jones, 1977; Aly et al, 1977) and urogenital (Davis et al, 1977a; Larson et al, 1978) tracts of humans and other higher animals, and the gastro-intestinal tracts of lower animals of several types (Breznak and Pankratz, 1977; Tannock and Savage, 1974a). In most cases, however, little is known in detail about the phenomena, except for those involving organisms in the buccal cavity (Gibbons and Van Houte, 1975). Some of these are discussed elsewhere in this volume (Gibbons, Chapter 4; Slade, Chapter 5).
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References
Abrams, G.D. (1977), Am. J. clin. Nutr., 30, 1880–1886.
Allweiss, B., Dostal, J., Carey, K.E. and Freter, R. (1977), Nature, 266, 448–450.
Aly, R., Shinefield, H.I., Strauss, W.G. and Maibach, H.I. (1977), Infect. Immun., 17, 546–549.
Artwohl, J.E. and Savage, D.C. (1979), Appl. Environ. Microbiol., 37, 697–703.
Bauchop, T. (1977), In: Microbial Ecology of the Gut, (Clarke, R.T.J. and Bauchop, T. eds.), Academic Press, London, New York, San Francisco, pp. 223–250.
Bauchop, T., Clarke, R.T.J. and J.C. Newhook, (1975), Appl. Microbiol., 30, 668–675.
Blumershine, R.V. and Savage, D.C. (1978), Microb. Ecol., 4, 95–103.
Breznak, J.A. and Pankratz, H.S. (1977), Appl. Environ. Microbiol., 33, 406–426.
Brooker, B.E. and Fuller, R. (1975), J. Ultrastruct. Res., 52, 21–31.
Brownlee, A. and Moss, W. (1961), J. Path. Bact., 82, 513–516.
Chase, D.G. and Erlandsen, S.L. (1976), J. Bact., 127, 572–583.
Cherry, R.J. (1975), FEBS Letters, 55, 1–7.
Clark, J.M. and Glasgov, S. (1976), Science, 192, 1360–1361.
Davis, C.P. (1976), Appl. Environ. Microbiol., 31, 304–312.
Davis, C.P. and Savage, D.C. (1974), Infect. Immun., 10, 948–956.
Davis, C.P. and Savage, D.C. (1976), Infect. Immun., 13, 180–188.
Davis, C.P., Balish, E. and Uehling, D. (1977a), Scanning Electron Microscopy, II, 269–274.
Davis, C.P., Cleven, D., Balish, E. and Yale, C.E. (1977b), Appl. Environ. Microbiol., 34, 194–206.
Davis, C.P., Mulcahy, D., Takeuchi, A. and Savage, D.C. (1972), Infect. Immun., 6, 184–192.
Dubos, R., Schaedler, R.W., Costello, R. and Hoet, P. (1965), J. exp. Med., 122, 67–76.
Ducluzeau, R., Ladire, M., Cullut, C., Raibaud, P. and Abrams, G.D. (1977), Infect. Immun., 17, 415–424.
Fuller, R. (1975), J. gen. Microbiol., 87, 245–250.
Fuller, R. and Turvey, A. (1971), J. Appl. Bacteriol., 34, 617–622.
Fuller, R., Barrow, P.A. and Brooker, B.E. (1978), Appl. Environ. Microbiol., 35, 582–591.
Garland, C.D., Stark, A.E., Lee, A. and Dickson, M.R. (1978), In: Microbial Ecology, (Loutit, M.W. and Miles, J.A.R. eds), pp. 240–243, Springer-Verlag, Berlin, Heidelberg, New York.
Geissinger, H.D. and Abandowitz, H.M. (1977), Trans. Am. Micros. Soc., 96, 254–257.
Gibbons, R.J. and Van Houte, J. (1975), Ann. Rev. Microbiol., 29, 19–44.
Gustafsson, B.E. and Maunsbach, A.B. (1971), Z. Zellforsch., 120, 555–578.
Hampton, J.C. and Rosario, B. (1965), Lab. Invest., 14, 1464–1481.
Hartley, C.L., Neumann, C.S. and Richmond, M.H. (1979), Infect. Immun., 23, 128–132.
Henrikson, R.C. (1973), Z. Zellforsch., 140, 445–449.
Ito, S. (1969), Fedn. Proc. Fedn. Am. Socs. exp. Biol., 28, 12–15.
Jones, G.W. (1977), In: Microbial Interactions (Receptors and Recognition), (Reissig, J.L. ed.), pp. 141–176, Chapman and Hall, London.
Kasai, K. and Kobayashi, R. (1919), J. Parasitol., 6, 1–11.
Kotarski, S.F. and Savage, D.C. (1978), Abstr. A. Meet. Am. Soc. Microbiol., 1978, 15.
Kunstyr, I. (1974), Zbl. Vet. Med., 21, 553–561.
Larsen, B., Markovetz, A.J. and Galask, R.P. (1978), Appl. Environ. Microbiol., 35, 444–450.
Leach, W.D., Lee, A. and Stubbs, R.P. (1973), Infect. Immun., 7, 961–972.
Lee, A. and Phillips, M. (1978), Appl. Environ. Microbiol., 35, 610–613.
Lee, F.D., Kraszewski, A., Gordon, J., Howie, J.G.R., McSeveney, D. and Harland, W.A. (1971), J. Br. Soc. Gastroenterol., 12, 126–133.
MacKinnon, J.E. (1959), Mycopathologia, 10, 207–208.
McBee, R.H. (1977), In: Microbial Ecology of the Gut, (Clark, R.T.J. and Bauchop, T. eds), pp. 185–222, Academic Press, London, New York, San Francisco.
McColl, I. and Sladen, G.E.G., (ed.) (1975), Intestinal Absorption in Man, Academic Press, London, New York, San Francisco.
McCowan, R.P., Cheng, K.-J., Bailey, C.B.M. and Costerton, J.W. (1978), Appl. Environ. Microbiol., 35, 149–155.
Minio, F., Tonietti, G. and Torsoli, A. (1973), Rendic. Gastroenterol, 5, 183–195.
Misiewicz, J.J. (1976), In: Disorders of the Gastro-intestinal Tract, The Science and Practice of Clinical Medicine, Vol. 1, (Dietschy, J.M. ed.), pp. 27–29, Grune and Stratton, New York.
Moore, W.E.C., Cato, E.P. and Holdeman, L.V. (1978), Am. Clin. Nutr., 31, S33—S42.
Morotomi, M., Watanabe, T., Suegara, N., Kawai, Y. and Mutai, M. (1975), Infect. Immun., 11, 962–968.
Nelson, D.P. and Mata, L.J. (1970), Gastroenterology, 58, 56–61.
Ofek, I., Beachey, E.H., Eyal, F. and Morrison, J.C. (1977), J. Infect. Dis., 135, 267–274.
Owen, R.L. and Nemanic, P. (1978), Scanning Electron Microscopy, II, 367–378.
Peach, S., Lock, M.R., Katz, D., Todd, I.P. and Tabaqchali, S. (1978), Gut, 19, 1034–1042.
Perers, L., Andaker, L., Edebo, L., Stendahl, O. and Tagesson, C. (1977), Acta path. microbiol, scand. Sect. B., 85, 308–316.
Phillips, M., Lee, A. and Leach, W.D. (1978), Aust. J. exp. Biol Med. Sci., 56, 649–662.
Plaut, A.G., Gorbach, S.L., Nahas, L., Weinstein, L., Spanknebel, G. and Levitan, R. (1967), Gastroenterology, 53, 868–873.
Reimann, H.A. (1965), J. Am. Med. Ass., 192, 100–102.
Roach, S., Savage, D.C. and Tannock, G.W. (1977), Appl. Environ. Microbiol., 33, 1197–1203.
Roseman, S. (1974), In: Biology and Chemistry of Eucaryotic Cell Surfaces, pp. 317–335, Academic Press, New York, London.
Salanitro, J.P., Blake, I.G., Muirhead, P.A., Maglio, M. and Goodman, J.R. (1978), Appl. Environ. Microbiol., 35, 782–790.
Savage, D.C. (1969a), J. Bact., 97, 1505–1506.
Savage, D.C. (1969b), J. Bact., 98, 1278–1283.
Savage, D.C. (1975), Microbiology, 1975, (Schlessinger, D., ed.), pp. 120–123, Am. Soc. Microbiol., Washington, D.C.
Savage, D.C. (1977a), A. Rev. Microbiol., 31, 107–133.
Savage, D.C. (1977b), Microbiology, 1977, (Schlessinger, D., ed.), pp. 422–426, Am. Soc. Microbiol., Washington, D.C.
Savage, D.C. (1977c), In: Microbial Ecology of the Gut, (Clark, R.T.J. and Bauchop, T. eds), pp. 277–310, Academic Press, London, New York, San Francisco.
Savage, D.C. (1978a), Am. J. clin. Nutr., 31, S131—S135.
Savage, D.C. (1978b), Micro-organisms and the Gastro-intestinal Tract, Gastrointestinal Microecology: One Opinion, In: Microbial Ecology, (Loutit, M.W. and Miles, J.A.R., eds), pp. 234–239, Springer-Verlag, Berlin, Heidelberg, New York.
Savage, D.C. (1979a), Am. J. clin. Nutr., 32, 113–118.
Savage, D.C. (1979b), In: Absorption of Micro-organisms to Surfaces, (Bitton, G. and Marshall, K.C. eds), Wiley-Interscience, New York, In Press.
Savage, D.C. and Blumershine, R.V. (1974), Infect. Immun., 10, 240–250.
Savage, D.C. and Dubos, R.J. (1967), J. Bact., 94, 1811–1816.
Savage, D.C., Dubos, R. and Schaedler, R.W. (1968), J. exp. Med., 127, 67–76.
Savage, D.C., McAllister, J.S. and Davis, C.P. (1971), Infect. Immun., 4, 492–502.
Scott, A. and Gardner, I.C. (1976), Microbios Letters, 2, 157–162.
Sedar, A.W. and Friedman, M.H.F. (1961), J. Biophys. Biochem. Cytol., 11, 349–363.
Slack, J.M. and Snyder, I.S. (1978), Bacteria and Human Disease, Year Book Medical Publishers, Inc., Chicago and London, 39–46.
Smith, H. (1977), Bact. Rev., 41, 475–500.
Snellen, J.E. and Savage, D.C. (1978), J. Bact., 134, 1099–1107.
Suegara, N., Morotomi, M., Watanabe, T., Kawai, Y. and Mutai, M. (1975), Infect. Immun., 12, 173–179.
Suegara, N., Siegel, J.E. and Savage, D.C. (1979), Infect. Immun., 24, In Press.
Syed, S.A., Abrams, D.G. and Freter, R. (1970), Infect. Immun., 2, 376–386.
Takeuchi, A. and Savage, D.C. (1973), Abstr. A. Meet. Am. Soc. Microbiol., 1973, 115.
Takeuchi, A. and Zeller, J.A. (1972), Infect. Immun., 6, 1008–1018.
Tannock, G.W. and Savage, D.C. (1974a), Infect. Immun., 9, 475–476.
Tannock, G.W. and Savage, D.C. (1974b), Infect. Immun., 9, 591–598.
Tannock, G.W. and Savage, D.C. (1976), Infect. Immun., 13, 172–179.
Tannock, G.W. and Smith, J.M.B. (1970), J. comp. Pathol., 80, 359–367.
Turek, J.J. and Meyer, R.C. (1978), Infect. Immun., 20, 853–855.
Untawale, G.G., Pietraszek, A. and McGinnis, J. (1978), Proc. Soc. exp. Biol. Med., 159, 276–280.
Vial, J.D. and Orrego, H. (1960), J. Biophysic. Biochem. Cytol., 7, 367–381.
Wagner, R.C. and Barrnett, R.J. (1974), J. Ultrastruct. Res., 48, 404–413.
Watanabe, T., Morotomi, M., Suegara, N., Kawai, Y. and Mutai, M. (1977), Microbiol. Immun., 21, 183–191.
Yoon, C.S. and Tannock, G.W. (1978), Can. J. Microbiol., 24, 1099–1101.
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Savage, D.C. (1980). Adherence of Normal Flora to Mucosal Surfaces. In: Beachey, E.H. (eds) Bacterial Adherence. Receptors and Recognition, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5863-0_2
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DOI: https://doi.org/10.1007/978-94-009-5863-0_2
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