Skip to main content
  • 138 Accesses

Abstract

Since prehistoric times man has used plant extracts to heal and to kill. Folklore abounds in references to the use of plant extracts in the healing of a variety of illnesses; examples of applications as agents of death range from that of calabar beans and hemlock as judicial poisons to that of the South American curare arrow poisons [1]. In modern times organic compounds isolated from cultures of microorganisms, as well as from plants, have been used for the cure of disease (e.g. penicillin and tetracycline antibiotics). These organic compounds from natural sources form a large group known as natural products, or secondary metabolites.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Swan, G. A. (1967), An Introduction to the Alkaloids, Blackwell Scientific Publications, Oxford.

    Google Scholar 

  2. Mahler, H. R and Cordes, E. H. (1971), Biological Chemistry, 2nd Edn, Harper and Row, New York.

    Google Scholar 

  3. Staunton, J. (1978), Primary Metabolism: a mechanistic approach, Clarendon Press, Oxford.

    Google Scholar 

  4. Dagley, S. and Nicholson, D. E. (1970), An Introduction to Metabolic Pathways, Blackwell Scientific Publications, Oxford.

    Google Scholar 

  5. Reed, L.J. (1974), Acc. Chem. Res., 7, 40–6.

    Article  Google Scholar 

  6. Arnstadt, K.-I., Schindlbeck, G. and Lynen, F. (1975), Eur. J. Biochem., 55, 561–71.

    Article  Google Scholar 

  7. Bu’Lock, J. D. and Smith, G. N. (1967), J. Chem. Soc. (C), 332–6.

    Google Scholar 

  8. Bergström, S. (1967), Science, 157, 382–91.

    Article  Google Scholar 

  9. Hamberg, M., Svensson, J., Wakabayashi, T. and Samuelsson, B. (1974), Proc. Natl. Acad. Sci. U.S.A., 71, 345–9.

    Article  Google Scholar 

  10. Hamberg, M., Svensson, J. and Samuelsson, B. (1975), Proc. Natl. Acad. Sci. U.S.A., 72, 2994–8.

    Article  Google Scholar 

  11. Bentley, R. (1969), Molecular Asymmetry in Biology, Academic Press, Vol. 1; (1970), vol. 2.

    Google Scholar 

  12. Hanson, K. R. (1966), J. Am. Chem. Soc., 88, 2731–42.

    Article  Google Scholar 

  13. Ogston, A. G. (1948), Nature, 162, 963.

    Article  Google Scholar 

  14. Cornforth, J. W. (1970), Chem. in Brit., 6, 431–6.

    Google Scholar 

  15. Townsend, C. A., Scholl, T. and Arigoni, D. (1975), J. Chem. Soc. Chem. Comm., 921–2.

    Google Scholar 

  16. Battersby, A. R., Staunton, J., Wiltshire, H. R., Bircher, B. J. and Fuganti, C. (1975), J Chem. Soc. Perkin 1, 1162–71; and their ref. 11.

    Article  Google Scholar 

  17. Olah, G. (1972), Chem. in Brit., 8, 281–7.

    Google Scholar 

  18. Barton, D. H. R. and Cohen, T. (1957), in Festschrift Dr A. Stoll, Birkhaüser, Basle, pp. 117–43.

    Google Scholar 

  19. Erdtman, H. and Wachtmeister, C. A. (1957), in Festschrift Dr A. Stoll, Birkhaüser, Basle, pp. 144–65.

    Google Scholar 

  20. Taylor, W. I. and Battersby, A. R. (eds.) (1967), Oxidative Coupling of Phenols, Arnold, London.

    Google Scholar 

  21. Poupat, C. and Kunesch, G. (1971), Compt. rend, 273C, 433–6.

    Google Scholar 

  22. Auret, B. J., Boyd, D. R., Robinson, P. M., Watson, C. G., Daly, J. W. and Jerina, D. M. (1971), J Chem. Soc. Chem. Comm., 1585–7.

    Google Scholar 

  23. Guroff, G., Daly, J. W., Jerina, D. M., Renson, J., Witkop, B. and Udenfriend, S. (1967) Science, 157, 1524–30.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1981 R. B. Herbert

About this chapter

Cite this chapter

Herbert, R.B. (1981). Introduction. In: The Biosynthesis of Secondary Metabolites. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5833-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-5833-3_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-5835-7

  • Online ISBN: 978-94-009-5833-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics