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Brain: Intracellular and Extracellular Purinergic Receptor-systems

  • Chapter
Purinergic Receptors

Abstract

The activities of the brain are carried out with the help of many forms of communication including chemical messengers, both intracellular and intercellular. Some forms of communication receive specific elaboration in the brain, especially the electrically-based forms involving cell polarization and nerve impulses. Others are common to a wide range of living organisms, and concern the adjustment of material intake, and turnover or translocation, to functional performance. In each of these categories of communication purine derivatives are found to have their specific points of action, and it is these which are appraised in the account which follows.

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Abbreviations

Ad:

adenine

Ads:

adenosine

AMP:

adenosine 5′-phosphate

ADP:

adenosine 5′-pyrophosphate

ATP:

adenosine 5′-triphosphate

ATPase:

adenosine triphosphatase

cAMP or cyclic AMP:

adenosine 3′: 5′-phosphate

cGMP or cyclic GMP:

guanosine 3′: 5′-phosphate

cIMP or cyclic IMP:

inosine 3′: 5′-phosphate

Gu:

guanine

Gus:

guanosine

GMP:

guanosine 5′-phosphate

Hx:

hypoxanthine

In:

inosine

IMP:

inosine 5′-phosphate

N* :

nicotinamide

NAD:

nicotinamide adenine dinucleotide

NMN:

nicotinamide mononucleotide

pr:

protein

Xa:

xanthine

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Authors
  1. Henry McIlwain
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Editors and Affiliations

  1. Department of Anatomy and Embryology, University College London, UK

    G. Burnstock

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© 1981 Chapman and Hall

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McIlwain, H. (1981). Brain: Intracellular and Extracellular Purinergic Receptor-systems. In: Burnstock, G. (eds) Purinergic Receptors. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5816-6_5

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  • DOI: https://doi.org/10.1007/978-94-009-5816-6_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-5818-0

  • Online ISBN: 978-94-009-5816-6

  • eBook Packages: Springer Book Archive

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