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Prevention of coronary heart disease and risk of cholelithiasis

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Book cover Epidemiology and Prevention of Gallstone Disease

Abstract

Certain clinical and experimental observations appear to indicate that dietary1–3 and/or pharmacological4,5 measures aimed at reducing metabolic risk factors of coronary heart disease (first and foremost cholesterolaemia) may alter bile composition thus favouring gallstone formation. Epidemio-logical data, too, seem to point in this direction although they are not univocal6–10.

For the composition of the Group see p. xi

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References

  1. Grundy, S. M. (1975). Effects of polyunsaturated fats on lipid metabolism in patients with hypertriglyceridemia. J. Clin. Invest., 51, 273–292

    Google Scholar 

  2. Lewis, B. (1958). Effect of certain dietary oils on bile-acid secretion and serum-cholesterol. Lancet, 1, 1090–1092

    Article  PubMed  CAS  Google Scholar 

  3. Lindstedt, S., Avigan, J., Goodman, D. S., Sjovall, J. and Steinberg, D. (1965). The effect of dietary fat on the turnover of cholic acid and on the composition of the biliary bile acids in man. J. Clin. Invest., 44, 1754–1765

    Article  PubMed  CAS  Google Scholar 

  4. Pertsemlidis, D., Panveliwalla, D. and Ahrens, E. H. Jr. (1974). Effects of Clofibrate and of an estrogen-progestin combination on fasting biliary lipids and cholic acid kinetics in man. Gastroenterology, 66, 565–573

    PubMed  CAS  Google Scholar 

  5. Angelin, B., Einarsson, K. and Leijd, B. (1979). Biliary lipid composition during treatment with different hypolipidaemic drugs. Eur. J. Clin. Invest., 9, 185–190

    Article  PubMed  CAS  Google Scholar 

  6. Sturdevant, R. A. L., Pearce, M. L. and Dayton, S. (1973). Increased prevalence of cholelithiasis in men ingesting a serum-cholesterol-lowering diet. N. Engl. J. Med., 288, 24–27

    Article  PubMed  CAS  Google Scholar 

  7. The Coronary Drug Project Research Group (1977). Gallbladder disease as a side effect of drugs influencing lipid metabolism. N. Engl. J. Med., 296, 1185–1190

    Article  Google Scholar 

  8. Cooper, J.,Geizerova, H. and Oliver, M.F. (1975). Clofibrate and gallstones. Lancet, 1, 1083

    Google Scholar 

  9. The Committee of Principal Investigators (1978). A co-operative trial in the primary prevention of ischaemic heart disease using Clofibrate. Br. Heart J., 40, 1069–1118

    Article  Google Scholar 

  10. Miettinen, M., Turpeinen, O., Karvonen, M. J., Paavilainen, E. and Elosuo, R. (1976). Prevalence of cholelithiasis in men and women ingesting a serum-cholesterol-lowering diet. Ann. Clin. Res., 8, 111–116

    PubMed  CAS  Google Scholar 

  11. W.H.O. European Collaborative Group (1974). An international controlled trial in the multifactorial prevention of coronary heart disease. Int. J. Epidemiol., 3, 219–224

    Article  Google Scholar 

  12. Research Group of the Rome Project of Coronary Heart Disease Prevention (1976). The Rome Project of Coronary Heart Disease Prevention. Ann. Ist. Sup. Sanit., 12, 316–330

    Google Scholar 

  13. Mariotti, S., Verdecchia, A., Capocaccia, R., Conti, S., Farchi, G. and Menotti, A. (1977). Identificazione di soggetti ad alto rischio nel Progetto Romano di Prevenzione della Cardiopatia Coronarica. G. Ital. Cardiol., 7, 141–146

    PubMed  CAS  Google Scholar 

  14. Gruppo di Ricerca del Progetto Romano di Prevenzione della Cardiopatia Coronarica (1982). Il Progetto Romano di Prevenzione della Cardiopatia Coronarica. Risultati finali. G. Ital. Cardiol., 12, 541–554.

    Google Scholar 

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L. Capocaccia G. Ricci F. Angelico M. Angelico A. F. Attili

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© 1984 MTP Press Limited

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Urbinati, G.C., the GREPCO Group. (1984). Prevention of coronary heart disease and risk of cholelithiasis. In: Capocaccia, L., Ricci, G., Angelico, F., Angelico, M., Attili, A.F. (eds) Epidemiology and Prevention of Gallstone Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5606-3_25

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  • DOI: https://doi.org/10.1007/978-94-009-5606-3_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8972-2

  • Online ISBN: 978-94-009-5606-3

  • eBook Packages: Springer Book Archive

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