Abstract
The ability of Prostaglandins (PGs) to induce labor in the human led in the late 1960s to highly efficient methods for induction of abortion in the first and second trimesters (Bydgeman et al., 1968; Karim et al., 1968). Since then, PGs have been used by various routes for induction of labor (review by Karim et al., 1979). In some cases the application of PGs resulted in favorable cervical scores without onset of labor (Haspels and Neth, 1973; Toppozada et al., 1973), which would suggest that cervical ripening may occur independent of prominent uterine contractions (Stys et al., 1978; Ulmsten, 1979).
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Rath, W., Theobald, P., Kühnle, H., Kuhn, W. (1984). Prostaglandin-induced changes in the pregnant human cervix. In: Toppozada, M.K., Bygdeman, M., Hafez, E.S.E. (eds) Prostaglandins and Fertility Regulation. Advances in Reproductive Health Care, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5600-1_5
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DOI: https://doi.org/10.1007/978-94-009-5600-1_5
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