Abstract
Gastric operations render the gastric mucosa abnormal.1 Of special concern is the development of severe dysplasia and cancer in longstanding post-gastrectomy patients. Only screening of asymptomatic post-gastrectomy patients may allow detection of early malignancy. The yield of such endoscopic screening is probably too low and the technique is probably too invasive for widespread use, except in countries with a very high incidence of gastric malignancy. The low yield of endoscopic screening in asymptomatic patients, the average high age of the population at risk, and the high morbidity and mortality rates for total gastrectomy with increasing age, render the value of screening procedures doubtful.
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References
Farrands PA, Blake JRS, Ansell ID et al. Endoscopic review of patients who have had gastric surgery. Br Med J 1983; 286: 755–758.
Van de Stadt J. Premaligne en maligne verandering in de restmaag. Disseratie Universiteit van Amsterdam, 1984.
Van de Stadt J, Offerhaus J, Huibregtse K et al. Carcinoom en premaligne veranderingen in biopten uit de maag van patienten die meer dan 15 jaar geleden een maagoperatie ondergingen. Ned T Geneesk 1984; 128: 606–611.
Morson BC, Sobin LH, Grundmann E et al. Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol 1980; 33: 711–721.
Domellof L, Erikson S, Janunger K-G. Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection. Gastroenterology 1977; 73: 462–468.
Offerhaus GJA, Huibregtse K, de Boer J et al. The operated stomach: A pre-malignant condition. A prospective endoscopic follow-up study. Scand J Gastroenterol 1984; 19: 521–524.
Offerhaus GJA, van de Stadt J, Huibregtse K et al. Endoscopic screening for malignancy in the gastric remnant: The clinical significance of dysplasia in gastric mucosa. J Clin Pathol 1984; 37: 748–754.
Nicholls JC. Stump cancer following gastric surgery. World J Surg 1979; 3: 731–736.
Peitsch W, Becker HD. Was ist gesichert in der Pathogenese und Haufigkeit des primaren Carzinoms im operierten Magen? Chirurg 1979; 50: 33–38.
Peitsch W, Becker HD. Frequency and prognosis of gastric stump cancer. Front Gastrointest Res 1979; 5: 170–177.
Fisher AB, Graem N, Jensen OM. Risk of gastric cancer after Billroth II resection for duodenal ulcer. Br J Surg 1983; 70: 552–554.
Pickford IR, Craven JL, Hall R et al. Endoscopic examination of the gastric remnant 31–39 years after subtotal gastrectomy for peptic ulcer. Gut 1984; 25: 393–397.
Lowenfels AB. Does bile promote extra-colonic cancer? Lancet 1978; 2: 667–670.
Langhans P, Heger RA, Hogenstein J et al. Gastric stump carcinoma — New aspects deduced from experimental results. Scand J Gastroenterol 1981; 16 (Suppl 67): 161–164.
Domellof L, Eriksson S, Janunger K-G. Late precancerous changes and carcinoma of the gastric stump after Billroth I resection. Am J Surg 1976; 132: 26–31.
Meister H, Schlag P, Weber E et al. Frequency of cancerous and precancerous epithelial lesions in the stomach in different models for enterogastric reflux. Scand J Gastroenterol 1981; 16 (Suppl 67): 165–168.
Offerhaus GJA. van de Stadt J, Huibregtse K et al. Is de geopereerde maag een premaligne toestand? N Tijdschr Geneesk 1983; 127: 2127–2132.
Scott RE, Whille JJ, Wier ML. Mechanisms for the invitation and promotion of carcinogenesis. A review and a new concept. Mayo Clin Proc 1984; 59: 107–117.
Correa P. Precursors of gastric and esophageal cancer. Cancer 1982; 50: 2554–2565.
Editorial. Bacteria in the stomach. Lancet 1981; 2: 906–907.
Tannenbaum SR. N-nitroso compounds: A perspective on human exposure. Lancet 1983; 1: 629–632.
Challis BC, Kyrkafoulos SA. The chemistry of nitroso-compounds. Part II. Nitrosation of amines by the two-phase interaction of amines in solution with gaseous oxides of nitrogen. J chem Soc 1979; 1: 299–304.
Glass GBJ, Pitchumoni CS. Atrophic gastritis. Human Path 1975; 6: 219–250.
Hansen OA, Larsen JK, Svendsen LB. Changes in gastric mucosal cell proliferation after antrectomy or vagotomy in man. Scand J Gastroenterol 1978; 13: 947–952.
Assad RT, Eastwood GL. Epithelial proliferation in human fundic mucosa after antrectomy and vagotomy. Gastroenterology 1980; 79: 807–811.
Offerhaus GJA, van de Stadt J, Samson G et al. Cell proliferation kinetics in the gastric remnant. Europ J Can Clin Oncol 1984; 21: 73–79.
Miderer SE, Miiller R, Kutz K et al. Multicentric early gastric carcinoma mimicking type I. Endoscopy 1977; 9: 50–53.
Osnes M, Ltveit T, Myren J et al. Early gastric carcinoma in patients with a Billroth II partial gastrectomy. Endoscopy 1977; 9: 45–49.
Oehlert W, Keller P, Henke M et al. Gastric mucosal dysplasia: What is its clinical significance? Front Gastroint Res 1979; 4: 173–182.
Schrumpf E, Serck-Hanssen A, Stadaas J et al. Mucosal changes in the gastric stump 20–25 years after partial gastrectomy. Lancet 1977; 2: 467–469.
Domellof L, Enander L–K, Wilsson F. Bleeding as a complication to endoscopic biopsies from the gastric remnant after ulcer surgery. Scand J Gastroenterol 1983; 18: 951–954.
Schafer LW, Larson DE, Melton LJ et al. the risk of gastric carcinoma after surgical treatment for benign ulcer disease. N Engl J Med 1983; 309: 1210–1213.
McLean Ross AH, Smith MA, Anderson JR et al. Late mortality after surgery for peptic ulcer. New Engl J Med 1982; 307: 519–522.
Logan RFA, Langman MJS. Screening for gastric cancer after gastric surgery. Lance 1983; 2: 667–670.
Dick W, Rosch W. Rezidivulkus und -karzinom im operierten Magen. Med Welt 1981; 32: 611–612.
Myren J. Markers of cancer risk and surveillance of the gastric stump. In: Sherlock P, Morson BC, Barbara L, Veronesi U (Eds). Precancerous lesions of the gastrointestinal tract. New York, Raven Press, 1983.
Correa P, Haenszel W. The epidemiology of gastric cancer. In: Correa P, Haenszel W (Eds). The epidemiology of cancer of the digestive tract. The Hague, Martinus Nijhoff 1982: 59–84.
Kekki M, Saukkonen M, Sipponen P et al. Dynamics of chronic gastritis in the remnant after partial gastrectomy for duodenal ulcer. Scand J Gastroenterol 1980; 15: 509–512.
Lewis JH, Woods M. Gastric carcinoma in patients with unoperated duodenal ulcer disease. Am J Gastroenterol 1982; 77: 368–373.
Kekki M, Ihamaki T, Saukkonen M et al. Progression of gastritis at a population level. Scand J Gastroenterol 1980; 15: 651–655.
Giarelli L, Melato M, Stanta G et al. Gastric resection: A cause of high frequency of gastric carcinoma. Cancer 1983; 52: 1113–1116.
Sonnenberg A. Endoscopic screening for gastric stump cancer. Would it be beneficial ? Gastroenterology 1984; 87: 489–495.
Pichelmayr R, Meyer HJ. Value of the gastrectomy ‘de Principe’. In: Herfarth Ch, Schlag P (Eds). Gastric cancer. Berlin, Springer-Verlag 1979: 196–204.
Domellof L, Janunger K-G. The risk for gastric carcinoma after partial gastrectomy. Am J Surg 1977; 134: 581–584.
Ewerth S, Bergstrand D, Hellers G et al. The incidence of carcinoma in the gastric remnant after resection for benign ulcer disease. Acta Chir Scand 1978; 482 (Suppl): 2–5.
Savage A, Jones S. Histological appearance of the gastric mucosa 15–27 years after partial gastrectomy. J Clin Path 1979; 32: 179–186.
Geboes K, Rutgeerts P, Broechaert L et al. Histological appearance of endoscopic mucosal biopsies 10–20 years after partial gastrectomy. Ann Surg 1980; 192 (2): 179–182.
Helsingen N, Hillestad L. Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann Surg 1956; 143: 173–179.
Krause U. Late prognosis after partial gastrectomy for ulcer. Acta Chir Scand 1957; 114: 341–354.
LiavSg K. Cancer development in gastric stump after partial gastrectomy for peptic ulcer. Ann Surg 1962; 155: 103–106.
Griesser G, Schmidt A. Statistische Erhebungen liber die Haufigkeit des Karzinoms nach Magenoperation wegen eines Geschwiirsleidens. Med Welt 1964; 35: 1836–1840.
Hilbe G, Salzer GM, Hussl H et al. Die Karzinomgefahrdung des Resektionsmagens. Lengenbecks Arch Chir 1968; 323: 142–153.
Stalsberg H, Taksdal S. Stomach cancer following gastric surgery for benign conditions. Lancet 1971; 2: 1175–1177.
Peitsch W, Burkhardt K. Zur Pathogenese und Klinik des Magenstumpfscarzinoms. Langenbecks Arch Chir 1976; 341: 195–203.
Hakkiluoto A. Long-term follow-up study of patients operated on for benign peptic ulcer. Ann Chir Gynaecol 1976; 65: 361–368.
Clemengon G, Baumgartner R, Leuthold E et al. Das Karzinom des operierten Magens. Dtsch Med Wochensch 1977; 9: 169–172.
Schmid E, Vollmer R, Adlung J et al. Zur endoskopische Diagnostik des Karzinoms in operierten Magen. Z Gastroenterol 1976; 5: 521.
Cheli R, Molinari F, Santi L. Gastric stump cancer: statistical evaluation. Rendiconti Gastroenterol 1977; 9: 169–72.
Welvaart K, Warnsinck HH. Hoe vaak komt maagstomp-carcinoom voor? Ned T Geneesk 1982; 126: 2374–2376.
Rehner M, Soehendra N, Eichfusz HP et al. Fruhkarzinome im (Billroth II-) Resektionsmagen. Dtsch Med Wochensch 1974; 99: 533–534.
Stokkeland M, Schrumpf R, Serck-Hanssen A et al. Incidence of malignancies of the Billroth II operated stomach: A prospective follow-up. Scand J Gastroenterol 1981; 67 (Suppl 16): 169–171.
Graem N, Fischer AB, Hastrup N. Mucosal changes of the Billroth II resected stomach. A follow-up study of patients resected for duodenal ulcer with special reference to gastritis, atypia and cancer. Acta Path Microbiol Scand 1981; 89: 227–234.
Hiltz SW, Schuman BM. The occurrence of gastric stump cancer in a US population. Gastrointest Endosc 1982; 28: 113A.
Pop P. Het carcinoom in de resectiemaag. Dissertatie Rijksuniversiteit Limburg, Maastricht, 1983.
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Tijtgat, G.N.J. (1985). Morphological changes in the stomach remnant after partial gastric resection. In: Nelis, G.F., Boevé, J., Misiewics, J.J. (eds) Peptic Ulcer Disease: Basic and Clinical Aspects. Developments in Gastroenterology, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5034-4_19
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DOI: https://doi.org/10.1007/978-94-009-5034-4_19
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