Abstract
Tc99m-MDP, the most commonly used radiopharmaceutical for bone imaging, localizes in regions of rapid bone mineral turnover, Thus, bone scanning is useful for screening patients with osteosarcoma because the tumour shows a high uptake of boneseeking agents (1,2). Since chemotherapy is often effective in the treatment of patients with primary osteogenic sarcoma, it has become essential that means for evaluating the response of the tumour to chemotherapy are available. A favorable effect of a preoperative chemotherapy achieving regression of the primary tumour allows a resection of the involved bone instead of amputation and gives a knowledge if it is advisable to continue the regimen of the chemotherapeutic agents postoperatively (3).
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Senekowitsch, R., Kriegel, H., Möllenstädt, S. (1985). Altered Uptake of Tc99m-MDP, Ca47 and Ga67 by Mice Osteogenic Sarcoma after Administration of a Cytostatic Drug. In: Cox, P.H., Limouris, G., Woldring, M.G. (eds) Progress in radiopharmacology 1985. Developments in Nuclear Medicine, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5028-3_17
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DOI: https://doi.org/10.1007/978-94-009-5028-3_17
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