Abstract
Technetium labelled phosphate complexes have proved to be extremely sensitive agents for the detection of pathophysiological changes in bone. As a result skeletal scintigraphy has become the method of choice to screen patients for the early detection of disease (1).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Pauwels EKJ, Schütte HE, Taconis WK, Bone Scintigraphy, Boerhaave Series, Vol. 20, Leiden University Press, The Hague, The Netherlands, 1981.
Cox PH, The pharmacological behaviour of technetium reagents in bone, bone marrow and joints, its significance in relation to the detection of malignant disease. In: Progress in Radiopharmacology, Vol. 1. Cox PH (ed), Elsevier/North-Holland Biomedical Press, Amsterdam, New York, pp 109–128, 1979.
Cox PH, Abnormalities in skeletal uptake of 99m Tc-polyphosphate com-plexes in areas of bone associated with tissues which have been subjected to radiation therapy. Brit. J. Rad. 47: 851, 1974.
Byun HH, Rodman SG, Chung KE, Soft tissue concentration of 99m Tc phosphates associated with injections of iron dextran conplex. J. nucl. Med. 17: 374, 1976.
MacGillivray I, Hall MH, Obstetric and gynaecological disorders. In: Drug Treatment - Principles and practice of clinical pharmacology and therapeutics. Avery GS (ed), Adis Press, New York, pp 445–492, 1980.
Lutrin CL, McDougall IR, Goris ML, Intense accumulation of Tc-99m pyrophosphate in the kidneys of children treated with chemotherapeutic drugs for malignant disease. Radiology 128: 165, 1978.
Sorkin SJ et al, Augmented activity on bone scan following local chemoperfusion, Clin. Nucl. Med. 2: 451, 1977.
Samson CB, A study of paediatric radiopharmaceuticals in America. Brit. J. Pharm. Pract. (Jan.) pp 17–25, 1980.
De Graaf P, Pauwels EKJ, Schicht IM, Scintigraphic detection of gastric calcification in dialysis patients. J. nucl. Med. 21: 197, 1980.
Chaudhuri TK, The effect of aluminium and pH on altered body distribution of 99m Tc-EHDP. Int. J. Nucl. Med. Biol. 3: 37, 1976.
Sebes JI et al, Radiographic manifestations of aluminium induced bone disease. Amer. J. Roentgenol. 142: 424, 1984.
Landgarden S, Gordon A, Radionuclide demonstrations of adriamycin induced toxicity. Clin. Nucl. Med. 2: 429, 1977.
Silberstein EA, Bove KE, Visualisation of alcohol induced rhabdomyolysis. J. nucl. Med. 20: 127, 1979.
Parker JA et al, Reduced uptake of bone seeking radiopharmaceuticals related to iron excess. Clin. Nucl. Med. 1: 267, 1976.
Saha GB et al, Unusual in vivo distribution of 99m Tc diphosphonate. Clin. Nucl. Med. 2: 303, 1977.
Powell ML, Bone imaging. In: Handbook of Clinical Nuclear Medicine. Malin P (ed), Medical Examination Publishing Co., Flushing New York, pp 238–262, 1977.
Carr EA et al, The use of adjunctive drugs to alter the uptake of 99m Tc-Sn-pyrophosphate by myocardial lesions and bone. Life Sci. 22: 1261, 1978.
Cox PH, The influence of drugs on the biodistribution of radiopharma-ceuticals. In: Yearbook of Radiopharmacy and Radiopharmacology. Cox PH (ed), Vol. 2, (in print) 1985.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Martinus Nijhoff Publishers, Dordrecht
About this chapter
Cite this chapter
Cox, P.H. (1985). The Effects of Drugs and Therapeutic Procedures on the Biodistribution of Skeletal Reagents. In: Cox, P.H., Limouris, G., Woldring, M.G. (eds) Progress in radiopharmacology 1985. Developments in Nuclear Medicine, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5028-3_15
Download citation
DOI: https://doi.org/10.1007/978-94-009-5028-3_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8727-8
Online ISBN: 978-94-009-5028-3
eBook Packages: Springer Book Archive