Skip to main content

Part of the book series: Current Topics in Veterinary Medicine and Animal Science ((CTVM,volume 31))

Abstract

The Authors described the effect of bromocriptine treatment in lactating sows. Bromocriptine (10 mg) were administered per os twice daily during the five days preceding weaning (21 days post-partum). The treatment could reduce the percentage of animals which did not return to estrus within 10 days of weaning and. among animals returning within 10 days, it reduced the weaning to estrus interval of about one day. In one piggery, where the post-partum reproductive efficiency was optimal, the treatment did not affect the percentage pf sows returning to estrus within 10 days of weaning. Trials carried out in a high (April-May) and a low (July-August) fertility period revealed that the effectiveness of the treatment was not related to the season. The bromocriptine treatment during the last stages of lactation did not affect the milk production as evaluated by the litter body weight gain and by the suckling behaviour.

The treatment reduced plasma PRL and maintained it at levels similar to those observed after weaning. Estradiol and LH profiles, however, were not different in control and treated sows. The effect of bromocriptine treatment, i.e. PRL withdrawal, on the sensitivity to GnRH of the pituitary gland was also investigated. A single injection of GnRH (500 pg) could induce a more marked increase of plasma LH in control than in treated sows. Finally the effect of bromocriptine treatment during the lactational anestrus on the stimulatory estrogen feed back of LH was evaluated. Data obtained indicated that bromocriptine enhanced, although not significantly, the stimulatory estrogen feed-back.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ash. R.W. and Heap. R.B. 1975. Estrogen, progesterone and corticosteroid concentrations in peripheral plasma of sows during pregnancy, parturition. lactation and after weaning. J.Endocr., 64, 141 – 154.

    Article  PubMed  CAS  Google Scholar 

  • Bevers. M.M., Willemse, A.H. and Kruip. A.M. 1973. Plasma prolactin levels in the sow during lactation and the postweaning period as measured by radioimmunoassay. Biol. Reprod., 19, 628–634.

    Article  Google Scholar 

  • Bevers. M.M., Willemse. A.H.. Kruip, A.M. and van de Wiel, D.F.M. 1981. Prolactin levels and the LH-response to synthetic LH-RH in the lactating sow. Anim.Reprod.Sci., 4. 155 – 163.

    Article  CAS  Google Scholar 

  • Bevers. M.M., Willemse, A.H. and Kruip, A.M. 1983. The effect of bromocriptine on luteinizing hormone levels in the lactating sows: evidence for a suppressive action by prolactin and the suckling stimulus. Acta Endocr., 104, 261–265.

    PubMed  CAS  Google Scholar 

  • Burger, J.F. 1952. Sex physiology of pig. Onderstepoort J.Vet.Res. Suppl. 2, 3–218.

    Google Scholar 

  • Corteel, J.M., Signoret, J.P., du Mesnil du Buisson, F. 1964. Variations seaisonnieres de la r production de la truie et facteurs favorisant l’anestrus temporale. In Proceedings 5th Internat.Congr.Anim.Reprod. Artificial Insemination. 536–540.

    Google Scholar 

  • Dsza, L. and Krzimowsk, H. 1981. Plasma prolactin levels in sows during pregnancy, parturition and early lactation. J.Reprod. Fert., 61, 131–134.

    Article  Google Scholar 

  • Edqvist, L.E., Einarsson, S. and Settergren, I. 1974. Ovarian activity and peripheral plasma levels of estrogens and progesterone in the lactating sows. Theriogenology,1, 43–49

    Article  PubMed  CAS  Google Scholar 

  • Elsaesser, F. and Parvizi, N. 1980. Partial recovery of the stimulatory estrogen feedback action on LH release during late lactation in the pig. J.Reprod.Fert., 59, 63–67

    Article  CAS  Google Scholar 

  • Hill. T.G., Alliston, C.W. and Malven, P.V. 1980. Plasma luteinizing hormone and prolactin in normothermic and hyperthermic ovariectomized ewes. Life Sci., 26, 1893.

    Google Scholar 

  • Hurtgen, J.P., Leman, A.D. and Crabo. B. 1980. Seasonal influence on estrus activity in sows and gilts. JAVMA. 176, 119–123.

    PubMed  CAS  Google Scholar 

  • Kann. G., Martinet, J. and Schair, A. 1976. Inpairment of luteinizing hormone release following estrogen administration to hyperprolactinemic ewes. Nature, Lond., 264, 465–466.

    Article  CAS  Google Scholar 

  • Kann, G.. Martinet, J. and Schair, A. 1977. Modifications of gonadotropin secretion during natural and artificial hyperprolactinemia in the ewe. In “Prolactin and human reproduction” (Academic Press. London), pp. 47–59

    Google Scholar 

  • Kraeling, R.R., Rampacek, G.B., Cox, N.M. and Kiser, T.E. 1982. Prolactin and luteinizing hormone secretion after bromocriptine treatment in lactating sows and ovariectomized gilts. J.Anim.Sci., 54, 1212–1220.

    PubMed  CAS  Google Scholar 

  • Labrie, F., Ferland. L., Di Paolo, T. and Villeux, R. 1980. Modulation of PRL secretion by sex steroids and thyroid hormones. In “Central and peripheral regulation of prolactin function” (Ed.R.M.MacLeod and U. Scapagnini ). ( Raven Press.New York ), pp. 97–113.

    Google Scholar 

  • Lauerdale, J.W., Kirkpatrick, R.L., First. N.L., Houser, E.R. and Casida L. E. 1965. Ovarian and pituitary gland changes in periparturient sows. J.Anim.Sci., 24, 1100–1103.

    Google Scholar 

  • Love, R.J. 1978. Definition of a seasonal infertility problem in pigs. Vet. Rec., 103, 443–446.

    Article  PubMed  CAS  Google Scholar 

  • Lu, K.H.. Chen. H.T., Huang. H.H., Crandison, L., Marshall. S. and Meites. J. 1976. Relation between prolactin and gonadotropin secretion in postpartum lactating rats. J.Endocr., 68. 241–250.

    Article  PubMed  CAS  Google Scholar 

  • Owens, R.E., Fleeger. J.C. and Harms, P.G. 1980. Evidence for central nervous system involvment in inhibition of luteinizing hormone release by dopamine receptor stimulation. Endocr. Res. Comm., 7, 99.

    Google Scholar 

  • Parvizi. N., Elsaesser. F., Smidt, D. and Ellendorff, F. 1976. Plasma LH and progesterone in the adult female pig during the estrus cycle, late pregnancy and lactation and after ovariectomy and pentobarbitone treatment. J.Endocr.. 69, 193–230.

    Article  Google Scholar 

  • Ravault, J.P.. Martinat-Botte, F., Mauget. R.. Martinat, M.. Locatelli, A. and Bariteau, F. 1982. Influence of the duration of daylight on prolactin secretion in the pig:hourly rythm in ovariectomize female, monthly variations in domestic (male and female) wild strains during the year. Biol.Reprod., 27, 1084–1089.

    Google Scholar 

  • Roland, R., Lequin. R.M., Schellerens, L.A. and de Jong. F.H. 1975- The role of prolactin in the restoration of ovarian function during the early post-partum in the human female. I. A study during physiological lactation. Clin. Endocr., 4, 15–25.

    Google Scholar 

  • Smith, B.B. and Wagner. W.C. 1980. Lactation physiology in the pig. Proc. 9th Int.Congr.Anim.,Reprod. and A.I., Madrid, 3, 118.

    Google Scholar 

  • Stevenson, J.S., Britt. J.H. 1980. Luteinizing hormone, total estrogens and progesterone secretion during lactation and after weaning in the sow. Theriogenology, 24, 453–462.

    Google Scholar 

  • Stevenson, J.S., Cox. N.M. and Britt, J.H. 1981. Role of the ovary in controlling LH, FSH and prolactin secretion during and after lactation in pigs. Biol.Reprod., 24, 341–353.

    Google Scholar 

  • Stevenson, J.S., Britt, H.J. 1981. Interval to estrus in sows and performances of pigs after alteration of litter size during late lactation. J.Anim.Sci., 53, 177–181.

    PubMed  CAS  Google Scholar 

  • Tarocco, C., Beccaro, V., and Enne, G. 1979. Sterilità estiva dei suini. Suinicultura. 5 65–72.

    Google Scholar 

  • Taverne, M., Bevers, M., Bradshaw, J.M.C., Dielman, S.J., Willemse, A.H. and Porter, D.G. 1982. Plasma concentrations of prolactin, progesterone, relaxin and oestradiol 176 in sows treated with progesterone, bromocriptine or indomethacin during late pregnancy. J.Reprod. Fert., 65, 85–96.

    Article  CAS  Google Scholar 

  • Thorner. M.O., Rogol. A.D., Evans. S.V., Nunley. V.C., McLeod. R.M. 1980. Effect of prolactin on gonadal function in man. In “Central and peripheral regulation of prolactin function” (Ed. R.M.MacLeod and U.Scapagnini ). ( Raven Press. New York ), pp. 271–286.

    Google Scholar 

  • van Landeghem. A.J. and van de Wiel. D.F.M. 1978. Radioimmunoassay for porcine prolactin: plasma levels during lactation suckling and weaning and after TRH administration. Acta Endocr., 88, 653–657.

    Google Scholar 

  • Weiner. R.I. and Ganong, W.F. 1978. Role of brain monoamines and histamine in regulation of anterior pituitary secretion. Physiol.Rev., 58. 905.

    PubMed  CAS  Google Scholar 

  • Williams. G.L. and Ray. D.E. 1980. Hormonal and reproductive profiles of early post-partum beef heifers after prolactin suppression on steroid induced luteal function. J.Anim.Sci., 50. 906–918.

    PubMed  CAS  Google Scholar 

  • Wuttke. W.. riohn. G.K.. Honma. K.; Hilgendorf. W. and Lamberts. R. 1980. Interrelationship between prolactin and gonadotropins. In “Central and peripheral regulation of prolactin function” (Ed. R.M.MacLeod and U. Scapagnini). (Raven Press. New York), pp. 221–236.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 ECSC, EEC, EAEC, Brussels-Luxembourg

About this chapter

Cite this chapter

Mattioli, M., Seren, E. (1985). Effects of Bromocriptine Treatment During Lactational Anestrus in Pigs. In: Ellendorff, F., Elsaesser, F. (eds) Endocrine Causes of Seasonal and Lactational Anestrus in Farm Animals. Current Topics in Veterinary Medicine and Animal Science, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5026-9_19

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-5026-9_19

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8726-1

  • Online ISBN: 978-94-009-5026-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics