Skip to main content
SpringerLink
Log in

Impact of Radionuclide Techniques on Clinical Cardiology

  • Chapter
Book cover Radioisotope studies in cardiology

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 8))

  • 38 Accesses

Abstract

In recent years, considerable advances have been made in our ability to image the heart by means of radionuclide techniques. The utility of these procedures in clinical cardiology must be considered in relation to that of other diagnostic techniques: the basic clinical assessment, other noninvasive approaches such as echocardiography, digital sub-traction angiography, nuclear magnetic resonance, and cardiac catheterization. The clinician must choose the technique which provides the most useful diagnostic information in a given cardio-vascular disorder.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Berger HJ, Gottschalk A, Zaret BL, Radionuclide assessment of left and right ventricular performance. Radiol. Clin. North Amer. 18: 441, 1980

    CAS  Google Scholar 

  2. Bodenheimer MM, Banka VS, Helfant RH, Nuclear cardiology. I. Radionuclide angiographic assessment of left ventricular contraction: uses, limitations and future directions. Amer. J. Cardiol. 45: 661, 1980

    CAS  Google Scholar 

  3. Okada RD, et al, Exercise radionuclide imaging approaches to coronary artery disease. Amer. J. Cardiol. 46: 1188, 1980

    Article  PubMed  CAS  Google Scholar 

  4. Strauss HW, et al, Of linens and laces: the 8th anniversary of the gated blood-pool scan. Sem. Nucl. Med. 9: 296, 1979

    Article  CAS  Google Scholar 

  5. Bailey IK, Griffith LSC, Rouleau J, Strauss WH, Pitt B, Thallium 201 myocardial perfusion imaging at rest and exercise: Comparative sensitivity to electrocardiography in coronary artery disease. Circulation 55: 79, 1977

    PubMed  CAS  Google Scholar 

  6. Okada RD, Boucher CA, Strauss HW, Pohost GW, Exercise radionuclide imaging approaches to coronary artery diseases. Amer. J. Cardiol. 46: 1188, 1980

    Article  PubMed  CAS  Google Scholar 

  7. Berger BC, Watson DD, Taylor GJ, et al, Quantitative Thallium 201 exercise scintigraphy for detection of coronary artery disease. J. nucl. Med. 22: 585 1981

    PubMed  CAS  Google Scholar 

  8. Rizi HR, Kline RC, Thrall JH, et al, Thallium 201 myocardial scintigraphy: A critical comparison of seven-pinhole tomography and conventional planar imaging. J nucl. Med. 22: 493, 1981

    CAS  Google Scholar 

  9. Brady TL, Lo K, Thrall JH, Walton JA, Brymer JF, Pitt B, Exercise radionuclide ejection fraction: Correlation with exercise contrast ventriculography. Radiology 132: 703, 1979

    PubMed  CAS  Google Scholar 

  10. Brady TL, et al, Exercise radionuclide ejection fraction: Correlation with exercise contrast ventriculography. Radiology 132: 703, 1979

    PubMed  CAS  Google Scholar 

  11. Brady TL, et al, Exercise radionuclide ventriculography: Practical considerations and sensitivity of coronary artery disease detection. Radiology 132: 697, 1979

    PubMed  CAS  Google Scholar 

  12. Epstein SE, Implications of probability analysis on the strategy used for noninvasive detection of coronary artery disease. Role of simple or combined use of exercise electrocardiographic testing, radionuclide cineangiography and myocardial perfusion imaging. Amer. J. Cardiol. 46: 419, 1980

    Article  Google Scholar 

  13. Bodenheimer MM, Banka VS, Fooshee CM, Gillespie JA, Helfant RH, Detection of coronary heart disease using radionuclide determined regional ejection fraction at rest and during handgrip exercise: Correlation with coronary arteriography. Circulation 58: 640, 1978

    PubMed  CAS  Google Scholar 

  14. Peter CA, Jones RH, Effects of isometric handgrip and dynamic exercise on left ventricular function. J. nucl. Med. 21: 1131, 1980

    PubMed  CAS  Google Scholar 

  15. Albro PC, et al, Non-invasive assessment of coronary stenoses by myocardial imaging during pharmacologic coronary vasodilation. III. Clinical trials. Amer. J. Cardiol. 42: 751, 1978

    Article  PubMed  CAS  Google Scholar 

  16. DeAmbroggi L, et al, Assessment of diagnostic value of dipyridamole testing in angina pectoris. Clin. Cardiol. 5: 269, 1982

    Google Scholar 

  17. Pachinger O, et al, Assessment of myocardial ischemia during pharmacologic vasodilatation. In: Quantification of myocardial ischemia. Kreuzer H, Parmley WN, Rentrop P, Heiss HW, (eds), Witzstrock Publish House, Inc, New York, pp 82–91, 1980

    Google Scholar 

  18. Leppo J, et al, Serial thallium-201 myocardial imaging after dipyridamole infusion. Diagnostic utility in detecting coronary stenoses and relationship to regional wallmotion. Circulation 66: 649, 1982

    Article  PubMed  CAS  Google Scholar 

  19. Tavazzi L, et al, Dipyridamole test in angina pectoris. Diagnostic value and pathophysiologic implications. Cardiology 69: 34, 1982

    Article  PubMed  CAS  Google Scholar 

  20. Pitt B, et al, Impact of radionuclide techniques on evaluation of patients with ischemic heart disease. J. Amer. Coll. Cardiol. 1: 63, 1983

    Article  CAS  Google Scholar 

  21. Berger BC, et al, Quantitative thallium-201 exercise scintigraphy for detection of coronary artery disease. J. nucl. Med. 22: 585, 1981

    PubMed  CAS  Google Scholar 

  22. Maddahi J, et al, Improved non-invasive assessment of coronary artery disease by quantitative analysis of regional stress myocardial distribution and washout of thallium-201. Circulation 64: 924, 1981

    Article  PubMed  CAS  Google Scholar 

  23. Rigo P, et al, Influence of coronary collateral vessels on the results of thallium-201 myocardial stress imaging. Amer. J. Cardiol. 44: 452, 1979

    Article  PubMed  CAS  Google Scholar 

  24. Tubau JF, et al, Influence of coronary collaterals on 14 lead ECG and thallium-201 exercise test results. Circulation 60: 266 (suppl. II), 1979

    Google Scholar 

  25. Beller GA, Pohost GM, Mechanism of thallium-201 redistribution after transient myocardial ischemia. Circulation 56: 171, 1977

    Google Scholar 

  26. Beller GA, Watson DD, Pohost GM, Kinetics of thallium distribution and redistribution: Clinical applications in sequential myocardial imaging. In: Cardiovascular nuclear medicine. Strauss HW, Pitt B, (eds), Mosby CV, St. Louis, 1979

    Google Scholar 

  27. Beller GA, et al, Time course of thallium-201 redistribution after transient myocardial ischemia. Circulation 61: 791, 1980

    PubMed  CAS  Google Scholar 

  28. Ritchie JL, Narahara KA, Trobaugh GB, Williams DL, Hamilton GW, Thallium-201 myocardial imaging before and after coronary revascularization: Assessment of regional myocardial blood flow and graft patency. Circulation 56: 830, 1977

    PubMed  CAS  Google Scholar 

  29. Gibson RS, et al, Prospective assessment of regional myocardial perfusion before and after coronary revascularization surgery by quantitative thallium-201 scintigraphy. J. Amer. Coll. Cardiol. 1: 804, 1983

    Article  CAS  Google Scholar 

  30. Olson H, Lyons K, Aronow W, Waters H, Identification of high risk unstable angina patients for mortality and myocardial infarction (abstr.) Circulation 55: 173 (suppl. Ill), 1977

    Google Scholar 

  31. Grüntzig AR, Senning A, Siegenthaller WE, Non-operative dilatation of coronary artery stenosis percutaneous transluminal coronary angioplasty. New Engl. J. Med. 301: 61, 1979

    Google Scholar 

  32. Hör G, Kanemoto N, Kaltenbach M, Standke R, Maul FD, Klepzig H, jr, Transluminale Angioplastik: Erfolgskontrolle mit Verfahren der Nuklearmedizin nach nichtoperativer Dilatation kritischer Koronararterienstenosen. Herz 5: 168, 1980

    PubMed  Google Scholar 

  33. Hirzel HO, Grüntzig AR, Nuesch K, Thallium 201-imaging for the evaluation of myocardial perfusion after percutaneous transluminal angioplasty of coronary artery stenosis. Circulation 58: 180, 1978

    Google Scholar 

  34. Hirzel HO, Nuesch K, Grüntzig AR, Luetolf UM, Short- and longterm changes in myocardial perfusion after percutaneous transluminal coronary angioplasty assessed by thallium-201 exercise scintigraphy. Circulation 63: 1001, 1981

    Article  PubMed  CAS  Google Scholar 

  35. Cherrier F, Godenir JP, Amor M, Cuilliere M, Annouf S, Danchin N, Bertrand A, Interet des methodes isotopiques pour l’indication et l’evaluation des resultats de l’angioplastie transluminale coronaire. In: Non invasive methods in ischemic heart disease. Faivre G, Bertrand A, Cherrier F, Amor M, Neimann J, (eds), Specia, Nancy, pp 399 - 409, 1982

    Google Scholar 

  36. Pachinger O, Sochor H, Ogris E, Probst P, Klicpera M, Kaindl F, Evaluation of transluminal coronary angioplasty by quantitative 201-thallium scintigraphy. J. nucl. Med. 24: P17 (abstr.), 1983

    Google Scholar 

  37. Maddahi J, et al, Myocardial salvage by intracoronary thrombolysis in evolving acute myocardial infarction. Evaluation using intracoronary injection of thallium-201. Amer. Heart J. 102: 664, 1981

    Article  PubMed  CAS  Google Scholar 

  38. Markis JE, et al, Myocardial salvage after intracoronary thrombolysis with streptokinase in acute myocardial infarction. Assessment by intracoronary thallium-201. New Engl. J. Med. 305: 777, 1981

    CAS  Google Scholar 

  39. Pachinger O, Sochor H, Probst P, Ogris E, Klicpera M, Kaindl F, Scintigraphic evaluation of myocardial viability after coronary reperfusion using intracoronary streptokinase. Eur. Heart J. 2: 65, (suppl. A), 1981

    Google Scholar 

  40. Pachinger O, Sochor H, Probst P, Klicpera M, Ogris E, Selektive Thrombolyse bei akutem Koronarverschlusz. Acta Med. Austr. 9: 65, 1982

    Google Scholar 

  41. Reduto LA, et al, Coronary artery reperfusion in acute myocardial infarction. Beneficial effects of intracoronary streptokinase on left ventricular salvage and performance. Amer. Heart J. 102: 1168, 1981

    Article  PubMed  CAS  Google Scholar 

  42. Schüler G, et al, Thrombolysis in acute myocardial infarction using intracoronary streptokinase assessment by thallium-201 scintigraphy. Circulation 66: 658, 1982

    Article  PubMed  Google Scholar 

  43. Olson H, Lyons K, Aronow W, Waters H, Identification of high risk unstable angina patients for mortality and myocardial infarction. Circulation 55:56 (suppl. III), III-173 (abstr.) 1977

    Google Scholar 

  44. Corbett JR, Dehmer GJ, Lewis SE, et al, The prognostic value of submaximal exercise testing with radionuclide ventriculography before hospital discharge in patients with recent myocardial infarction. Circulation 64: 535, 1981

    Article  PubMed  CAS  Google Scholar 

  45. Turner JD, Schwartz KM, Logic JF, et al, The detection of residual jeopardized myocardium three weeks after myocardial infarction by exercise testing with thallium 201 myocardial scintigraphy. Circulation 61: 729, 1980

    PubMed  CAS  Google Scholar 

  46. Brown K, et al, Prognostic value of exercise thallium-201 imaging in patients presenting for evaluation of chest pain. J. Amer. Coll. Cardiol. 1 (4): 994, 1983

    Article  CAS  Google Scholar 

  47. Nicod P, et al, Prognostic assessment after myocardial infarction. Comparison between coronary angiography and submaximal exercise testing with radionuclide ventriculography. Amer. J. Cardiol. 49: 991, 1982

    Article  Google Scholar 

  48. Phillips P, et al, Prognostically critical coronary stenoses. Identification by radionuclide cineangiography. Amer. J. Cardiol. 49: 991, 1982

    Article  Google Scholar 

  49. Rigo P, Murray M, Taylor DR, Weisfeldt M, Strauss HW, Pitt B, Hemodynamic and prognostic findings in patients with transmural and nontransmural infarction. Circulation 51: 1064, 1975

    PubMed  CAS  Google Scholar 

  50. Pitt B, Thrall JH, Thallium 201 versus technetium 99m pyrophosphate myocardial in detection and evaluation of patients with acute myocardial infarction. Amer. J. Cardiol. 46: 1215, 1980

    Article  PubMed  CAS  Google Scholar 

  51. Tobinick E, Schelbert HR, Henning H, et al, Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography. Circulation 57: 1078, 1978

    PubMed  CAS  Google Scholar 

  52. Leitl GP, Buchanan JW, Wagner HN, Monitoring cardiac function with nuclear techniques. Amer. J. Cardiol. 46: 1125, 1980

    Article  PubMed  CAS  Google Scholar 

  53. Rigo P, Murray M, Strauss HW, Pitt B, et al, Scintiphotographic evaluation of patients with suspected left ventricular aneurysm. Circulation 50: 985, 1974

    PubMed  CAS  Google Scholar 

  54. Pachinger 0, Einsatz von Radionuklidmethoden in der kardiologischen Intensivstation. In: Verhandlungen der Deutschen Gesellschaft für Herz- und Kreislaufforschung. Band 59, Seite 99–106, 1983

    Google Scholar 

  55. Shah KP, Pichler M, Berman DS, Singh BH, Swan HJC, Left ventricular ejection fraction determined by radionuclide ventriculography in early stages of first transmural myocardial infarction. Amer. J. Cardiol. 45: 542, 1980

    Article  PubMed  CAS  Google Scholar 

  56. Nichols AB, McKusick KA, Strauss HW, Dinsmore RE, Block PC, Pohost GM, Clinical utility of gated cardiac blood imaging in congestive left heart failure. Amer. J. Med. 65: 785, 1978

    Article  PubMed  CAS  Google Scholar 

  57. Pitt B, Thrall JH, Thallium-201 versus technetium-99m pyrophosphate myocardial in detection and evaluation of patients with acute myo¬cardial infarction. Amer. J. Cardiol. 46: 1215, 1980

    Article  PubMed  CAS  Google Scholar 

  58. Bulkley DH, Hutchins GM, Daly I, Pitt D, Thallium-201 imaging and gated cardiac blood pool scans in patients with ischemic and idio-pathic congestive cardiomyopathy. A clinical and pathologic study. Circulation 55: 753, 1977

    PubMed  CAS  Google Scholar 

  59. Silverman KJ, et al, Value of early thallium-201 scintigraphy for preducting mortality in patients with acute myocardial infarction. Circulation 61 :996, 1980

    PubMed  CAS  Google Scholar 

  60. Boucher CA, Okada RD, Pohost GM, Current status of radionuclide imaging in valvular heart disease. Amer. J. Cardiol. 46: 1153, 1980

    Article  PubMed  CAS  Google Scholar 

  61. Ogris E, Sochor H, Pachinger 0, Probst P, Klicpera M, Assessment of left ventricular performance and regurgitant fraction in chronic aortic insufficiency before and after pharmacologic after load reduction. In: Radioactieve isotope. Höfer R, Bergman H, (eds), Klin. Forsch. 15:15, 1982

    Google Scholar 

  62. Klicpera M, Probst P, Pachlnger 0, Assessment of left ventricular reserve in patients with chronic aortic regurgitation using systemic vasodilation. Eur. Heart J. 2: 96, 1981

    Google Scholar 

  63. Rigo P, Alderson PO, Robertson RM, Becker LC, Wagner HN, Measurement of aortic and mitral regurgitation by gated cardiac blood pool scans. Circulation 60: 306, 1979

    PubMed  CAS  Google Scholar 

  64. Clark DG, McAnulty JH, Rahimtoola SH, Valve replacement in aortic insufficiency with left ventricular dysfunction. Circulation 61: 411, 1980

    PubMed  CAS  Google Scholar 

  65. Borer JS, Rosing DR, Kent KM, et al, Left ventricular function at rest and during exercise after aortic valve replacement in patients with aortic regurgitation. Amer. J. Cardiol. 44: 1297, 1979

    Article  PubMed  CAS  Google Scholar 

  66. Slutsky R, Karliner J, Ricci D, et al, Left ventricular volumes by gated equilibrium radionuclide angiography: A new method. Circulation 60: 556, 1979

    PubMed  CAS  Google Scholar 

  67. Hancock EW, Aortic stenosis, angina pectoris, and coronary artery disease. Amer. Heart J. 93:382, 1977

    Article  PubMed  CAS  Google Scholar 

  68. Bailey IK, et al, Thallium-201 myocardial perfusion imaging in aortic valve stenosis. Amer. J. Cardiol. 40: 889, 1977

    Article  PubMed  CAS  Google Scholar 

  69. Goldman MR, Boucher CA, Value of radionuclide imaging techniques in assessing cardiomyopathy. Amer. J. Cardiol. 46: 1232, 1980

    Article  PubMed  CAS  Google Scholar 

  70. Pachinger O, Ogris E, Sochor H. Probst P, Zasmeta H, Kaliman J, Klicpera M, Szintigraphische Aspekte bei Kardiomyopathien. Acta Med. Austr. 2:35, 1979

    Google Scholar 

  71. Pachinger O, Ogris E, Probst P, Sochor H, Joskowicz G, Kaindl F, Radionuclide assessment of left and right ventricular performance in congestive cardiomyopathies. Trans. Eur. Soc. Cardiol. 1 :38, 1978

    Google Scholar 

  72. Pachinger O, Ogris E, Sochor H, Probst P, Zasmeta H, Kaindl F, Radionuclide assessment of cardiac performance and myocardial perfusion in congestive cardiomyopathies. Clin. Cardiol. 2: 264, 1979

    Article  PubMed  CAS  Google Scholar 

  73. Alexander J, Dainiak N, Berger HJ, et al, Serial assessment of doxo- rubic in cardiac toxicity with quantitative radionuclide angiocardiography. New Eng. J. Med. 300: 278, 1979

    Article  CAS  Google Scholar 

  74. Pachinger O, Ogris E, Probst P, Sochor H, Joskowicz G, Kaindl F, Assessment of right ventricular performance in coronary artery disease and cardiomyopathies. In: Coronary heart diseases. Kaltenbach M, (ed), Thieme G, Stuttgart, pp 244–246, 1978

    Google Scholar 

Download references

Authors
  1. O. Pachinger
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute of Clinical and Experimental Nuclear Medicine, University of Bonn, Federal Republic of Germany

    H. J. Biersack

  2. Department of Nuclear Medicine, Rotterdam Radio-Therapeutic Institute, Rotterdam, The Netherlands

    P. H. Cox

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Martinus Nijhoff Publishers, Dordrecht

About this chapter

Cite this chapter

Pachinger, O. (1985). Impact of Radionuclide Techniques on Clinical Cardiology. In: Biersack, H.J., Cox, P.H. (eds) Radioisotope studies in cardiology. Developments in Nuclear Medicine, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5022-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-5022-1_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8724-7

  • Online ISBN: 978-94-009-5022-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation