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Myocardial Ischemia: A Profile of its Pathophysiological Basis and its Detection by Nuclear Cardiology

  • Chapter
Radioisotope studies in cardiology

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 8))

Abstract

As a muscular pump with the specific task of ensuring the optimal circulation of blood under the most variable conditions, the heart continuously consumes energy at a very high rate. A large quantity of high energy phosphates are produced continuously to meet its specific requirements which makes a normal oxygen and substrate delivery, removal of wastage and an undisturbed cellular metabolism essential. During myocardial ischemia however, myocardial blood-flow and hence the oxygen and substrate supply is reduced. Due to diminished venous efflux from the ischemic area metabolic endproducts accumulate and myocardial metabolism and function quickly deteriorates.

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Authors
  1. W. J. Remme
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Editors and Affiliations

  1. Institute of Clinical and Experimental Nuclear Medicine, University of Bonn, Federal Republic of Germany

    H. J. Biersack

  2. Department of Nuclear Medicine, Rotterdam Radio-Therapeutic Institute, Rotterdam, The Netherlands

    P. H. Cox

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© 1985 Martinus Nijhoff Publishers, Dordrecht

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Remme, W.J. (1985). Myocardial Ischemia: A Profile of its Pathophysiological Basis and its Detection by Nuclear Cardiology. In: Biersack, H.J., Cox, P.H. (eds) Radioisotope studies in cardiology. Developments in Nuclear Medicine, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5022-1_1

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  • DOI: https://doi.org/10.1007/978-94-009-5022-1_1

  • Publisher Name: Springer, Dordrecht

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