Abstract
Large Ia positive cells with irregular (dendritic) surface morphology have been identified in a variety of tissues including skin, heart, kidney, and small intestine in several species (1–4). Similar cells are present in the peripheral lymph draining from these tissues to local lymph nodes (5–8). However, they are much rarer in central lymph, leaving lymph nodes and entering the blood (9). A variety of non-lymphoid cells has been identified in the various compartments of both lymph nodes and spleen. These include the sinus lining macrophages, the follicular dendritic cells and tingible body macrophages of the germinal centres, the interdigitating cells of the lymph node paracortex and the splenic periarteriolar lymphoid sheath and the macrophages of the lymph node medulla and splenic red pulp. Each of these cell types have their own characteristics (1, 10, reviewed in 11).
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Pugh, C.W., MacPherson, G.G. (1985). The origins and turnover kinetics of limbocytes. In: van Furth, R. (eds) Mononuclear Phagocytes. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5020-7_22
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DOI: https://doi.org/10.1007/978-94-009-5020-7_22
Publisher Name: Springer, Dordrecht
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