Skip to main content
SpringerLink
Log in

Macrophage membranes and clathrin

  • Chapter
Mononuclear Phagocytes

  • 119 Accesses

Abstract

Clathrin-coated pits and vesicles were first described in detail by Roth and Porter (1, 2) in the mosquito oocyte, and their role in adsorptive endocytosis suggested. In the intervening twenty years, the molecular structure of the clathrin coat has been elucidated, and a number of functions for clathrin-coated structures have been proposed. Although the structure of the clathrin basketwork is now understood in some detail, the exact mechanism(s) of assembly and vesicle recognition are still largely unknown.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 699.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Roth TF, Porter KR: Specialized sites on the cell surface for protein uptake. In: Breese SS Jr, ed. Electron Microscopy. Academic Press, New York 1962, pp LL-4.

    Google Scholar 

  2. Roth TF, Porter KR: Yolk protein uptake in the oocyte of the mosquito Aedes aegypti L. J Cell Biol 1964, 20: 313–332.

    Article  PubMed  CAS  Google Scholar 

  3. Anderson RGW, Goldstein JL, Brown MS: Localization of low density lipoprotein receptors on plasma membrane of normal fibroblasts and their absence in cells from a familial hypercholesterolemia homozogote. Proc Natl Acad Sci USA 1976, 73: 2434–2438.

    Article  PubMed  CAS  Google Scholar 

  4. Fawcett DW: Surface specializations of absorbing cells. J Histochem Cytochem 1965, 13: 75–91.

    Article  PubMed  CAS  Google Scholar 

  5. Friend DS, Farquahar MG: Functions of coated vesicles during protein absorption in the rat vas deferens. J Cell Biol 1967, 35: 357–376.

    Article  PubMed  CAS  Google Scholar 

  6. Goldstein JL, Anderson RGW, Brown MS: Coated pits, coated vesicles, and receptor-mediated endocytosis. Nature (Lond.) 1979, 279: 679–685.

    Article  CAS  Google Scholar 

  7. Helenius A, Mellman I, Wall D, Hubbard A. Endosomes. TIBS 1983, 8: 245–250.

    CAS  Google Scholar 

  8. Marsh M, Helenius A: Absorptive endocytosis of Semliki Forest virus. J Mol Biol 1980, 142: 439–454.

    Article  PubMed  CAS  Google Scholar 

  9. Pearse BMF, Bretscher MS: Membrane recycling by coated vesicles. Ann Rev Biochem 1981, 50: 85–101.

    Article  PubMed  CAS  Google Scholar 

  10. Salisbury JL, Condeelis JS, Satir P. Role of coated vesicles, microfilaments and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells. J Cell Biol 1980, 87: 132–141.

    Article  PubMed  CAS  Google Scholar 

  11. Wall DA, Hubbard AL: Galactose-specific recognition systems of mammalian liver: receptor distribution on the hepatocyte cell surface. J Cell Biol 1981, 90: 687–696.

    Article  PubMed  CAS  Google Scholar 

  12. Aggeler J, Werb Z: Initial events during phagocytosis by macrophages viewed from outside and inside the cell: Membrane-particle interactions and clathrin. J Cell Biol 1982, 94: 613–623.

    Article  PubMed  CAS  Google Scholar 

  13. Dingemans KP, Fels E, van Dongen G, den Otter W: Destruction of murine lymphoma cells by allogeneic peritoneal macrophages in vitro: Influence of antiserum. J Natl Cancer Inst 1983, 70: 181–192.

    PubMed  CAS  Google Scholar 

  14. Montesano R, Mossaz A, Vassalli P, Orci L: Specialization of the macrophage plasma membrane at sites of interaction with opsonized erythrocytes. J Cell Biol 1983, 96: 1227–1233.

    Article  PubMed  CAS  Google Scholar 

  15. Besterman JM, Airhart JA, Woodworth RC, Low RB: Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation. J Cell Biol 1981, 91: 716–727.

    Article  PubMed  CAS  Google Scholar 

  16. Farquahar MG: Multiple pathways of exocytosis, endocytosis, and membrane recycling: validation of a Golgi route. Fed Proc 1983, 42: 2407–2413.

    Google Scholar 

  17. Rodewald R: Intestinal transport of antibodies in the newborn rat. J Cell Biol 1980, 85: 18–32.

    Article  PubMed  CAS  Google Scholar 

  18. Franke WW, Luder MR, Kartenbeck J, Zerban H, Keenan TW: Involvement of vesicle coat material in casein secretion and surface regeneration. J Cell Biol 1976, 69: 173–195.

    Article  PubMed  CAS  Google Scholar 

  19. Nichols BA: Uptake and digestion of horseradish peroxidase in rabbit alveolar macrophages. Formation of a pathway connecting lysosomes to the cell surface. Lab Invest 1982, 47: 235–246.

    PubMed  CAS  Google Scholar 

  20. Werb Z, Chin JR, Takemura R, Frisch SM, Oropeza RL, Bainton DF: Control of apolipoprotein E secretion by macrophages. This volume.

    Google Scholar 

  21. Rothman JE: The golgi apparatus: two organelles in tandem. Science 1982, 213: 1212–1219.

    Article  Google Scholar 

  22. Bretscher MS, Thomson JN, Pearse BMF: Coated pits act as molecular filters. Proc Natl Acad Sci USA 1980, 77: 4156–4159.

    Article  PubMed  CAS  Google Scholar 

  23. Heuser J: Three-dimensional visualization of coated vesicle formation in fibroblasts. J Cell Biol 1980, 84: 560–583.

    Article  PubMed  CAS  Google Scholar 

  24. Harrison SC, Kirchhausen T: Clathrin, cages, and coated vesicles. Cell 1983, 33: 650–652.

    Article  PubMed  CAS  Google Scholar 

  25. Aggeler J, Takemura R, Werb Z: High resolution three dimensional views of membrane-associated clathrin and cytoskeleton in critical-point dried macrophages. J Cell Biol 1983, 97: 1452–1458.

    Article  PubMed  CAS  Google Scholar 

  26. Michl J, Pieczonka MM, Unkeless JC, Silverstein SC: Effects of immobilized immune complexes on Fe-and complement-receptor function in resident and thioglycollateelicited mouse peritoneal macrophages. J Exp Med 1979, 150: 607–621.

    Article  PubMed  CAS  Google Scholar 

  27. Takemura R, Aggeler J, Werb Z: Initial events during frustrated phagocytosis by mouse macrophages. J Cell Biol 1982, 95: 423a.

    Google Scholar 

  28. Takemura R, Werb Z: Redistribution of clathrin during spreading of mouse macrophages on immobilized immune complexes. J Cell Biol 1983, 97: 174a.

    Google Scholar 

  29. Nichols BA: Normal rabbit alveolar macrophages. II. Their primary and secondary lysosomes as revealed by electron microscopy and cytochemistry. J Exp Med 1976, 144: 920–932.

    Article  PubMed  CAS  Google Scholar 

  30. Casley-Smith JR: Endocytosis: the different energy requirements for the uptake of particles by small and large vesicles into peritoneal macrophages. J Micros 1969, 90: 1530.

    Google Scholar 

  31. Dumont A: Ultrastructural study of the maturation of peritoneal macrophages in the hamster. J Ultrastruct Res 1969, 29: 191–209.

    Article  PubMed  CAS  Google Scholar 

  32. Lagunoff D, Curran DE. Role of bristle-coated membrane in the uptake of ferritin by rat macrophages. Exp Cell Res 1972, 75: 337–346.

    Article  PubMed  CAS  Google Scholar 

  33. Munthe-Kaas AC, Kaplan G: Endocytosis by macrophages. In: Carr I, Daems WT, eds. The Reticuloendothelial System. Plenum Publ Corp, New York 1980, pp 19–55.

    Google Scholar 

  34. Wisse E: Ultrastructure and function of Kupffer cells and other sinusoidal cells in the liver. In: Wisse E, Knook DL, eds. Kupffer Cells and Other Liver Sinusoidal Cells. Elsevier/North Holland Biomedical Press, Amsterdam 1977, pp 33–60.

    Google Scholar 

  35. Kolb-Bachofen V, Schlepper-Schafer J, Kolb H: Receptor-mediated particle uptake by liver macrophages. The galactose-particle receptor mediates uptake via coated and also non-coated structures. Exp Cell Res 1983, 148: 173–182.

    Article  PubMed  CAS  Google Scholar 

  36. Sung S-SJ, Nelson RS, Silverstein SC: The role of the mannose/N-acetylglucosamine receptor in the pinocytosis of horseradish peroxidase by mouse peritoneal macrophages. J Cell Physiol 1983, 116: 21–25.

    Article  PubMed  CAS  Google Scholar 

  37. Steinman RM, Brodie SE, Cohn ZA: Membrane flow during pinocytosis. A stereologic analysis. J Cell Biol 1976, 68: 665–687.

    Article  PubMed  CAS  Google Scholar 

  38. Steinman RM, Mellman IS, Muller WA, Cohn ZA: Endocytosis and the recycling of plasma membrane. J Cell Biol 1983, 96: 1–27.

    Article  PubMed  CAS  Google Scholar 

  39. Aggeler J, Heuser JE, Werb Z: Presence of clathrin at adhesion sites in phagocytosing macrophages. In: Bailey GW, ed. 40th Ann Proc Electron Microscopy Soc Amer Claitor’s Law Books and Publ Co Baton Rouge 1982, pp 114–117.

    Google Scholar 

  40. Werb Z, Cohn ZA: Plasma membrane synthesis in the macrophage following phagocytosis of polystyrene latex particles. J Biol Chem 1972, 247: 2439–2446.

    PubMed  CAS  Google Scholar 

  41. Werb Z, Chin J: Biosynthetic radiolabeling of cellular and secreted proteins of mononuclear phagocytes. In: Adams DO, Edelson PJ, Koren HS, eds. Methods for Studying Mononuclear Phagocytes. Academic Press, New York 1981, pp 861–872.

    Google Scholar 

  42. Nichols BA: Normal rabbit alveolar macrophages. I. The phagocytosis of tubular myelin. J Exp Med 1976, 144: 906–919.

    Article  PubMed  CAS  Google Scholar 

  43. Kanaseki T, Kadota K: The vesicle in a Basket. A morphological study of the coated vesicle isolated from the nerve endings of the guinea pig brain, with special reference to the mechanism of membrane movements. J Cell Biol 42: 202–220.

    Google Scholar 

  44. Pearse BMF: Coated vesicles from pig brain: purification and biochemical characterization. J Mol Biol 1975, 97: 93–98.

    Article  PubMed  CAS  Google Scholar 

  45. Crowther RA, Pearse BMF: Assembly and packing of clathrin into coats. J Cell Biol 1981, 91: 790–797.

    Article  PubMed  CAS  Google Scholar 

  46. Ungewickell E, Branton D: Assembly units of clathrin coats. Nature (London) 1981, 289: 420–422.

    Article  CAS  Google Scholar 

  47. Keen JH, Willingham MC, Pastan IH: Clathrin coated vesicles: isolation, dissociation and factor-dependent reassociation of clathrin baskets. Cell 1979, 16: 303–312.

    Article  PubMed  CAS  Google Scholar 

  48. Maupin P, Pollard TD: Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation. J Cell Biol 1983, 96: 51–62.

    Article  PubMed  CAS  Google Scholar 

  49. Henson PM: The immunologic release of constituents from neutrophil leukocytes. II. Mechanism of release during phagocytosis, and adherence to nonphagocytosable surfaces. J Immunol 1971, 107: 1547–1557.

    PubMed  CAS  Google Scholar 

  50. Ezekowitz RAB, Bampton M, Gordon S: Macrophage activation selectively enhances expression of Fc receptors for IgG2a. J Exp Med 1983, 157: 807–812.

    Article  PubMed  CAS  Google Scholar 

  51. Wehland J, Willingham MC, Dickson R, Pastan I: Micro-injection of anticlathrin antibodies into fibroblasts does not interfere with receptor mediated endocytosis of alpha-2 macroglobulin. Cell 1981, 25: 105–120.

    Article  PubMed  CAS  Google Scholar 

  52. Louvard D, Morris C, Warren G, Stanley K, Winkler F, Reggio H: A monoclonal antibody to the heavy chain of clathrin. EMBO J 1983, 2: 1655–1664.

    PubMed  CAS  Google Scholar 

  53. Pfeiffer JR, Oliver JM, Berlin RD: Topographical distribution of coated pits. Nature (Lond.) 1980, 286: 727–729.

    Article  CAS  Google Scholar 

Download references

Authors
  1. J. Aggeler
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Takemura
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. A. Nichols
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Z. Werb
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Infectious Diseases, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands

    Ralph van Furth

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Martinus Nijhoff Publishers, Dordrecht

About this chapter

Cite this chapter

Aggeler, J., Takemura, R., Nichols, B.A., Werb, Z. (1985). Macrophage membranes and clathrin. In: van Furth, R. (eds) Mononuclear Phagocytes. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5020-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-5020-7_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8723-0

  • Online ISBN: 978-94-009-5020-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation