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Use of Radio-Labeled Antibodies in Diagnosis and Staging of Solid Tumors

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Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy

Part of the book series: Developments in Oncology ((DION,volume 31))

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Abstract

Pressman and Keighley1 demonstrated in 1948 that anti-kidney antibodies could be radio-labeled with 131I without loss of immunoreactivity, and when administered to an animal, localize renal tissue. In 1953, the same investigators detected a mouse osteo-sarcoma using radio-labeled anti-tumor antibodies.2 Since then, many reports have been published on uptake of radio-labeled anti-tumor antibodies in animal models.3–5

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References

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© 1985 Martinus Nijhoff Publishers, Dordrecht

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Halpern, S.E., Dillman, R.O. (1985). Use of Radio-Labeled Antibodies in Diagnosis and Staging of Solid Tumors. In: Pattengale, P.K., Lukes, R.J., Taylor, C.R. (eds) Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Therapy. Developments in Oncology, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5016-0_10

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  • DOI: https://doi.org/10.1007/978-94-009-5016-0_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8721-6

  • Online ISBN: 978-94-009-5016-0

  • eBook Packages: Springer Book Archive

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