Abstract
Aseptic arthritis associated with genital-tract infection is probably the commonest form of acute arthritis affecting young adult males in the western world. In the light of recent highly significant advances in the fields of genetics and microbiology this condition is also of prime importance as the archetype of a genetically determined disorder, which is precipitated by external environmental influences. As awareness of this form of arthritis increases, so the considerable breadth of the spectrum of clinical features is becoming apparent, with, in particular, increasing recognition of patients with mild disease and an excellent prognosis. This disorder is also being diagnosed more frequently in women. In recent years, the definitions and terms used to apply to this form of arthritis have come under close scrutiny and it is clear that no existing term satisfactorily describes the whole spectrum of disease presently recognised as resulting from urogenital or gastrointestinal infection, without infection being present in the joint. Consequently, a plethora of terms has been introduced; an attempt at rationalisation of terminology is presented below. We consider that the term ‘reactive arthritis’ most accurately describes this multifaceted disorder.
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References
Aho K, Ahvonen P, Lassus A, Sievers K, Tiilikainen A: HL-A27 in reactive arthritis. A study of yersinia arthritis and Reiter’s disease. Arthr Rheum 17:521–526, 1974.
Arnett FC, Schacter BZ, Lordon RE: Incomplete Reiter’s syndrome: discriminating features and HL-AW27 in diagnosis. Ann Intern Med 84:8–12, 1976.
Hughes GRV: Concluding remarks. Symposium on Reiter’s syndrome, Lausanne, 1978. Ann Rheum Dis 38: Suppl 1, 149–150, 1979.
Willkens RF, Arnett FC, Bitter T, Calin A, Fisher L, Ford DK, Good AE, Masi A: Reiter’s syndrome. Evaluation of preliminary criteria for definite disease. Arthr Rheum 24:844–849, 1981.
Keat AC, Maini RN, Nkwazi GC, Pegrum GD, Ridgway GL, Scott JT: Role of Chlamydia trachomatis and HLA-B27 in sexually acquired reactive arthritis. Br Med J 1:605–607, 1978.
Keat AC, Maini RN, Pegrum GD, Scott JT: The clinical features and HLA associations of arthritis associated with non-gonococcal urethritis. Quart J Med 48:323–342, 1979.
Paronen I: Reiter’s disease. A study of 344 cases observed in Finland. Acta Med Scand 131: Suppl 212, 1–112, 1948.
Noer HR: An experimental epidemic of Reiter’s syndrome. J Amer Med Ass 197:693–698,1966.
Vartiainen J, Hurri L: Arthritis due to Salmonella typhimurium. Acta Med Scand 175:771–776, 1964.
Hakansson U, Low B, Eitrem B, Winblad S: HL-A27 and reactive arthritis in an outbreak of salmonellosis. Tissue Antigens 6:366–367, 1975.
Ahvonen P: Human yersiniosis in Finland. II. Clinical features. Ann Clin Res 4:39–48, 1972.
Winblad S: Arthritis associated with Yersinia enterocolitica infections. Scand J Infect Dis 7:191–195, 1975.
Urman JD, Zurier RB, Rothfield NF: Reiter’s syndrome associated with Campylobacter jejuni infection. Ann Intern Med 86:444–445, 1977.
Berden JHM, Muytjens HL, Van de Putte LBA: Reactive arthritis associated with Campylobacter jejuni enteritis. Br Med J 1:381, 1979.
Kaslow RA, Ryder RW, Calin A: Search for Reiter’s syndrome after an outbreak of Shigella sonnei dysentery. J Rheumatol 6:562–566, 1979.
Keat AC: Reiter’s syndrome and reactive arthritis in perspective. N Engl J Med 309:1606–1615, 1983.
Wright V: Seronegative polyarthritis. A unified concept. Arthr Rheum 21:619–633, 1978.
Dumonde DC, Steward MW: The role of microbial infection in rheumatic disease. In: Cope-man’s Textbook of the Rheumatic Diseases, 5th ed, J.T. Scott (ed.). Churchill Livingstone, Edinburgh, 1978, p. 221–258.
Kristjansen A: Non-gonococcal urethritis with conjunctivitis and arthritis. Ugesk J Laeger 92:276–278, 1930.
Dunlop EMC, Harper IA, Jones BR: Seronegative polyarthritis. The Bedsoniae (chlamydia) group of agents in Reiter’s disease. Ann Rheum Dis 27:234–240, 1968.
Rustin MHR, Wedzicha JA, Keat AC, Coomes ENC: Sexually transmitted arthritis? Two informative cases. J Rheumatol 9:646, 1982.
Ford DK: Natural history of arthritis following venereal urethritis. Ann Rheum Dis 12:177–194, 1953.
Csonka GW: The course of Reiter’s syndrome. Br Med J 1:1088–1090, 1958.
Neuwelt CM, Borenstein DG, Jacobs RP: Reiter’s syndrome: a male and female disease. J Rheumatol 9:268–272, 1982.
Smith DL, Bennett RM, Regan MG: Reiter’s disease in women. Arthr Rheum 23:335–340, 1980.
Yates DB, Maini RN, Scott JT, Sloper JC: Complement activation in Reiter’s syndrome. Ann Rheum Dis 34:468, 1975.
Baldassare AR, Weiss TD, Tsai CC, Arthur RE, Moore TL, Zuckner J: Immunoprotein deposition in synovial tissue in Reiter’s syndrome. Ann Rheum Dis 40:281–285, 1981.
Oates JK, Young AC: Sacroiliitis in Reiter’s disease. Br Med J 1:1013–1015, 1959.
Sharp J: Differential diagnosis of ankylosing spondylitis. Br Med J 1:975–978, 1957.
Good AE: Long-term follow-up in relation to development of ankylosing spondylitis; Symposium on Reiter’s syndrome. T. Bitter (ed.). Ann Rheum Dis(Suppl 1) 38:39–45, 1979.
Russell AS, Davis P, Percy JS, Lentle BC: The sacroiliitis of acute Reiter’s syndrome. J Rheumatol 4:293–296, 1977.
Dequeker J, Goddeeris T, Walravens M, De Roo M: Evaluation of sacro-iliitis: comparison of radiological and radionuclide techniques. Radiology 128:687–689, 1978.
Goldbergh R, Genant H, Shimshak R, Shames D: Applications and limitations of quantitative sacroiliac joint scintigraphy. Radiology 128:683–686, 1978.
Borlaza GL, Seigel R, Kuhns LR: Computed tomography in the evaluation of sacoiliac arthritis. Radiology 139:437–440, 1981.
Carrera GF: Computed tomography in sacroiliitis. Clin Rheum Dis 9:403–415, 1983.
Good AE: Reiter’s disease and ankylosing spondylitis. Acta Rheum Scand 11:305–317, 1965.
Steinbach HL, Jensen PS: Roentgenographic changes in the arthritides. Part II. Semin Rheum Arthr 5:203–246, 1976.
Marche J: L’atteinte des articulations sacroiliaque dans le syndrome dit de Reiter. Rev Rhum 17:449–456, 1950.
Bywaters EGL, Dixon AStJ: Paravertebral ossification in psoriatic arthritis. Ann Rheum Dis 23:313–331, 1965.
Cliffe JM: Spinal bony bridging and carditis in Reiter’s disease. Ann Rheum Dis 30:171–179, 1971.
Sundaram M, Patten JT: Paravertebral ossification in psoriasis and Reiter’s disease. Br J Radiol 48:628–633, 1975.
Niepel GA, Sit’aj S: Enthesopathy. Clin Rheum Dis 5:857–872, 1979.
Ball J: Enthesopathy of rheumatoid and ankylosing spondylitis. Ann Rheum Dis 30:213–223, 1970.
Cooper RR, Misol S: Tendon and ligament insertion. A light and electron microscopic study. J Bone Joint Surg (Am) 52:1–20, 1970.
Resnick D, Niwayama G: Entheses and enthesopathy. Radiology 146:1–9, 1983.
Fujimoto D, Moriguchi T: Pyridinoline: a non-reducable cross-link of collagen. J Biochem 83:863–867, 1978.
Boucek RJ, Noble NL, Gunja-Smith Z, Butler WT: The Marfan syndrome: a deficiency in chemically stable collagen cross-links. N Engl J Med 305:988–991, 1981.
Jacobs JC: Spondylarthritis and enthesopathy. Arch Intern Med 143:103–107, 1983.
Rosenberg AM, Petty RE: A syndrome of seronegative enthesopathy and arthropathy in children. Arthr Rheum 25:1041–1047, 1982.
Baxter CR: Reiter’s disease. Br Med J 2:858–860, 1946.
Epstein E, Chambers SO: Keratosis blenorrhagica with corneal lesions. Further observations on the therapeutic effect of hyperpyrexia. Arch Derm Syph (Chicago) 36:1044–1051, 1937.
Foxworthy DT, Poske RM, Barton RM, Baker LA, Montgomery MM: Adrenocorticotropin and cortisone in the treatment of severe Reiter’s syndrome. Ann Int Med 44:52–62, 1956.
Weinberger WH, Ropes MW, Kulka JP, Bauer W: Reiter’s syndrome, clinical and pathological observations. A long term study of 16 cases. Medicine (Baltimore) 41:35–91, 1962.
Zewi M: Morbus Reiteri. Acta Ophthalmol 25:47–60, 1947.
Oates JK, Hancock JAH: Neurological symptoms and lesions occurring in the course of Reiter’s disease. Am J Med Sci 238:79–82, 1959.
Catterall RD, Perkins ES: Uveitis and urogenital disease in the male. Br J Ophthalmol 45:109116, 1961.
Wright V, Reed WB: The link between Reiter’s syndrome and psoriatic arthritis. Ann Rheum Dis 23:12–20, 1964.
Kousa M: Clinical observations on Reiter’s disease with special reference to the venereal and non-venereal aetiology. Acta Derm-Venereol (Stockh) 58: Suppl 81, 1978.
Csonka GW: Reiter’s disease. Br J Hosp Med January: 8–12, 1972.
Thambar IV, Dunlop R, Thin RN, Huskisson EC: Circinate vulvitis in Reiter’s syndrome. Br J Vener Dis 53:260–262, 1977.
Auckland G: Keratoderma blennorrhagica: report of a case and suggestions concerning its nature. Br J Vener Dis 27:143–149, 1951.
Montgomery MM, Poske RM, Barton EM, Foxworthy DT, Baker LA: The mucocutaneous lesions of Reiter’s syndrome. Ann Intern Med 51:99–109, 1959.
Kulka JP: The lesions of Reiter’s syndrome. Arthr Rheum 5:195–201, 1962.
Kanerva L, Kousa M, Niemi KM, Lassus A, Juvakoski T, Lauharanta J: Ultrahistopathology of balanitis circinata. Br J Vener Dis 58:188–195, 1982.
Kousa M, Saikku P, Kanerva L: Erythema nodosum in chlamydial infections. Acta DermVenereol (Stockh) 60:319–322, 1980.
McMillan A: Reiter’s disease in a female presenting as erythema nodosum. Br J Vener Dis 51:345–347, 1975.
Russell TJ, Schultes LM, Kuben DJ: Histocompatibility (HL-A) antigens associated with psoriasis. N Engl J Med 287:738–739, 1972.
Tiilikainen A, Lassus A, Karvonen J, Vartiainen P, Julin M: Psoriasis and HLA-Cw6. Br J Derm 102:179–184, 1980.
Csonka GW, Litchfield JW, Oates JK, Willcox RR: Cardiac lesions in Reiter’s disease. Br Med J 28:243–247, 1961.
Laitinen O, Leirisola M, Allander E: Rheumatic fever and yersinia arthritis: criteria and diagnostic problems in a changing disease pattern. Scand J Rheum 4:145–157, 1975.
Rossen RM, Goodman DJ, Harrison DC: A-V conduction disturbances in Reiter’s syndrome. Am J Med 58:280–284, 1975.
Csonka GW, Oates JK: Pericarditis and electrocardio-graphic changes in Reiter’s syndrome. Br Med J 1, 866–869, 1956.
Neu LT, Reider RA, Mack R: Cardiac involvement in Reiter’s disease: report of a case with review of the literature. Ann Intern Med 53:215–220, 1960.
Block SR: Reiter’s syndrome and acute aortic insufficiency. Arthr Rheum 15:218–220, 1972.
Collins P: Aortic incompetence and active myocarditis in Reiter’s disease. Br J Vener Dis 48:300–303, 1972.
Yates DB, Scott JT: Cardiac valvular disorders in chronic inflammatory disorders of connective tissue. Ann Rheum Dis 34:321–325, 1975.
Rupert GB, Lindsay J, Barth WF: Cardiac conduction abnormalities in Reiter’s syndrome. Am J Med 73:335–340, 1982.
Csonka GW: Involvement of the nervous system in Reiter’s syndrome. Ann Rheum Dis 17:334–336,1958.
Lafon R, Pages P, Roux J, Temple JP, Thinvielle J: Syndrome de Fiessinger-Leroy-Reiter, avec infiltrates pulmonaires lobaires et hemiplegie regressive-organisons dans le secretions uretrales. Revue Neurologique 92:611–614, 1955.
Kleupel K: Zentral nervose Ausfalle beim Reiter-Syndrom. Schweiz Arch Neurol Neurochir Psychiatr 106:283–299, 1970.
Harris JR: Reiter’s syndrome. In: Recent Advances in Sexually Transmitted Diseases. RS Morton (ed.). Churchill Livingstone, Edinburgh, 1975 p. 303–319.
Mason RM, Barnes CG: Behcet’s syndrome with arthritis. Ann Rheum Dis 28:95–103, 1969.
Hall WH, Finegold S: Study of 23 cases of Reiter’s syndrome. Ann Intern Med 38:533–550,1953.
Thiers H, Pinet A: Syndrome de Reiter avec uretrite à inclusions, infiltrat pulmonaire labile à keratodermie. Lyon Med 184:51–55, 1950.
Colby FH: Renal complications of Reiter’s disease. J Urol 52:415–419, 1944.
Piora J: Cystitis and haematuria as the predominant symptoms of Reiter’s disease. Acta Med Scand 144:284–289, 1953.
Csonka GW: Thrombophlebitis in Reiter’s syndrome, Br J Vener Dis 42:93–95, 1966.
Bleehan SS, Everall JD, Tighe OR: Amyloidosis complicating Reiter’s syndrome. Br J Vener Dis 42:88–92, 1966.
Caughey DE, Wakem CJ: A fatal case of Reiter’s disease complicated by amyloidosis. Arthr Rheum 16:695–700, 1973.
Koster MS, Jansen MT: Reiter’s disease. Nederlandsch tijdschrift voor Geneeskunde, 90:483–485,1946.
Trier M: On Reiter’s syndrome, with special reference to cardiac complications and familial occurrence of the syndrome. Acta Med Scand 239:123–128, 1950.
Csonka GW: Multiple cases in Reiter’s syndrome. Br J Vener Dis 45:157–160, 1969
Lawrence JS: A family survey of Reiter’s disease. Br J Vener Dis 50:140–145, 1974.
Brewerton DA Caffrey M, Nicholls A, Walters D, Oates JK, James DCO: Reiter’s disease and HL-A27. Lancet ii:996–998, 1973.
Woodrow JC, Treanor B, Usher N: The HL-A system in Reiter’s syndrome. Tissue Antigens 4:533–540, 1974.
Morris R, Metzger AL, Bluestone R, Terasaki PI: HL-AW27 - a clue to the diagnosis and pathogenesis of Reiter’s syndrome. N Engl J Med 290:554–556, 1974.
Falk JA, Fleischman JL, Zabriskie JB, Falk RE: A study of HL-A antigen phenotypes in rheumatic fever and rheumatic heart disease patients. Tissue Antigens 3:173–178, 1973.
Früs J: HL-A27 in Neisseria infected patients with arthritis. Scand J Rheum 4: (Suppl 8), 30–12 (Abstr), 1975.
Robitaille A, Cockburn C, James DCO, Ansell BM: HLA frequencies in less common arthropathies. Ann Rheum Dis 35:271–273, 1976.
Keat AC, Maini RN, Nkwazi GC, Pegrum GD, Ridgway GL, Scott JT: HLA antigens Chlamydia trachomatis infection and reactive arthritis. Tissue Antigens 12:63–64, 1978.
McDevitt HO, Bodmer WF: HLA, immune response genes and disease. Lancet I:1269–1275, 1974.
Festenstein H, Demant P: HLA and H-2. Basic immunogenetics. Biology and clinical relevance. Edward Arnold, London, 1978.
Svejgaard A, Morling N, Platz P, Ryder LP, Thomsen M: HLA and disease associations with special reference to mechanisms. Transplant Proc 13:913–917, 1981.
Brewerton DA, Caffrey M, Nicholls A, Walters D, James DCO: Acute anterior uveitis and HL-A27. Lancet 6:994–996, 1973.
Woodrow JC, Mapstone R, Anderson J, Usher M: HL-A27 and anterior uveitis. Tissue Antigens 6:116–120, 1975.
Lassus A, Tiilikainen A, Stubb S, Reunala T, Johansen E: Circinate erosive balanitis and HL-A27. Acta Derm Venereol (Stockh) 55:199–201, 1975.
Moller E, Olhagen B: HL-A27 and seronegative rheumatic disorders (pelvospondylitis, sacroiliitis and uro-arthritis). In: Genital Infections and their Complications. D. Davidsson, L. Juhlin and P-A Mârdh (eds.). Almquist and Wiksell International, Stockholm, 1975, p. 215–221.
Heinrichs K, Zeidler H, Eckert G, Wittenborg A: HL-A27 in patients with oligoarthritis and lower back pain. Scand J Rheum 4: (Suppl 8), 30–21 (Abstr), 1975.
Brewerton DA: Many genes, many clinical features. Ann Rheum Dis 38:145–148, 1979.
McMichael A, Ting A, Zweerink HJ, Askonas BA: HLA restriction of cell-mediated lysis of influenza virus infected human cells. Nature 270:524–526, 1977.
Thorsby E, Bergholtz B, Berle E, Braathen L, Hirschbirg H: Involvement of HLA in T-cell immune responses. Transplant Proc 13:903–908, 1981.
Geczy AF, Alexander K, Bashir HV, Edmonds J: A factor(s) in klebsiella culture filtrates specifically modifies an HLA-B27-associated cell surface component. Nature 283:782–784, 1980.
Ebringer E, Cooke D, Cawdell DR, Cowling P, Ebringer A: Ankylosing spondylitis: klebsiella and HL-A B27. Rheum Rehab 16:190–196, 1977.
Edmonds J, MaCauley D, Tyndall A, Liew M, Alexander K, Geczy A, Bashir H: Lymphocytotoxicity of anti-klebsiella antisera in ankylosing spondylitis and related arthropathies. Arthr Rheum 24:1–7, 1981.
Archer JAR: Search for cross-reactivity in HLA-B27 and Keebsiella pneumoniae. Ann Rheum Dis 40:400–403, 1981.
Laitinen O, Leirisalo M, Skylv G: Relations between HLA-B27 and clinical features in patients with yersinia arthritis. Arthr Rheum 20:1121–1124, 1977.
Abel MS: Sacroiliac joint changes in traumatic paraplegics. Radiology 55:235–239, 1950.
Wright V, Catterall RD, Cook JB: Bone and joint changes in paraplegic men. Ann Rheum Dis 24:419–431, 1965.
Romanus R: Pelvo-spondylitis ossificans in the male and genito-urinary infection. Acta Med Scand 145: (Suppl 280) 172–178, 1953.
Domeij B, Giertz E, Olhagen B, Romanus R: Genito-urinary focus in rheumatic disorder in the male. Acta Chir Scand 115:1–10, 1958.
Mason RM, Murray RS, Oates JK, Young AC: Prostatitis in ankylosing spondylitis. Br Med J 1: 748–751,1958.
Grainger RG, Nicol CS: Pelvic infection as a cause of bilateral sacroiliac arthritis and ankylosing spondylitis. Br J Vener Dis 35:92–98, 1959.
Moller P, Vinje O, Fryjordet A: HLA antigens and sacroiliitis in chronic prostatitis. Scand J Rheum 9:138–140, 1980.
Julkunen H, Pietila K: Chronic salpingo-oophoritis and rheumatoid spondylitis. Acta Rheum Scand 10:209–214, 1964.
Szanto E, Hagenfeldt K: Sacroiliitis and salpingitis. Scand J Rheum 8:129–135, 1979.
Richmond SJ, Oriel JD: Recognition and management of genital chlamydial infection. Br Med J 2:480–483, 1978.
Harkness AH: In: Non-Gonococcal Urethritis. Livingstone, Edinburgh. 1950, p. 99–145.
Rosenthal L, Olhagen B, Ek S: Aseptic arthritis after gonorrhoea. Ann Rheum Dis 39:141–146, 1980.
Csonka GW: Long-term follow-up and prognosis of Reiter’s syndrome. Ann Rheum Dis 38: (Suppl.) 24–28, 1979.
Fox R, Calin A, Gerber RC, Gibson D: The chronicity of symptoms and disability in Reiter’s syndrome. An analysis of 131 consecutive patients. Ann Intern Med 91:190–193, 1979.
Rosenthal L, Lagergren C, Olhagen B: A clinical and roentgenological follow-up study of patients with uro-arthritis or pelvospondylitis. Acta Rheum Scand 17:3–14, 1971.
Popert AJ, Gill AJ, Laird SM: A prospective study of Reiter’s syndrome: an interim report on the first 82 cases. Br J Vener Dis 40:160–165, 1964.
Fowler W, Knight GH: Value of treatment in Reiter’s disease. Br J Vener Dis 32:2–6, 1956.
Ford DK: Antibiotic treatment in Reiter’s syndrome. Ann Rheum Dis 38: (Suppl.) 98–99,1979.
Mullins JF, Maberry JD, Stone OJ: Reiter’s syndrome treated with folic acid antagonists. Arch Dermatol 94:335–337, 1966.
Owen ET, Cohen ML: Methotrexate in Reiter’s disease. Ann Rheum Dis 38:48–50, 1979.
Taylor-Robinson D, Thomas BJ: The role of Chlamydia trachomatis in genital-tract and associated diseases. J Clin Pathol 33:205–233, 1980.
Taylor-Robinson D, Csonka GW: Laboratory and clinical aspects of mycoplasmal infections of the human genitourinary tract. In: Recent advances in sexually transmitted diseases. JRW Harris (ed.). Churchill Livingstone, London, 1981, p. 151–186.
Catterall RD: Diagnosis and treatment of trichomonal urethritis in men. Br Med J 3:113–115, 1960.
Jeansson S, Molin L: Genital herpes infection and non-specific urethritis. Br Med J 3:247, 1971.
Holmes KK, Handsfield HH, Wang S-P, Wentworth BB, Turk M, Anderson JB, Alexander ER: Etiology of non-gonococcal urethritis. N Engl J Med 292:1199–1205, 1975.
Schachter J, Hill EC, King EB, Coleman VR, Jones P, Meyer KF: Chlamydial infection in women with cervical dysplasia. Am J Obstet Gynecol 123:753–757, 1975.
Oriel JD, Johnson AL, Barlow D, Thomas BJ, Nayyar K, Reeve T: Infection of the uterine cervix with Chlamydia trachomatis. J Infect Dis 137:443–451, 1978.
Hovelius B, Màrdh P-A, Theln I: Staphylococcus saprophyticus in men with urethritis. In: Proceedings of the second meeting on Sexually Transmitted Diseases, Helsinki, Finland. Abstract. August 9–10, 1979.
Furness G, Evangelista A, Kaminski Z: Biologic reactions differentiating commensals of the urogenital tract from the pathogens responsible for urethritis. Invest Urol 15:23–27, 1977.
Hafiz S, McEntegart MG, Morton RS, Waitkin SA: Clostridium difficile in the urogenital tract of males and females. Lancet i:420–421, 1975.
Kinghorn JR, Jones BM, Chowdhury FH, Geary I: Balanoposthitis associated with Gardnerella vaginalis infection in men. Br J Vener Dis 58:127–129, 1982.
Tully JG, Taylor-Robinson D, Cole RM, Rose DL: A newly discovered mycoplasma in the human urogenital tract. Lancet i:1288–1291, 1981.
Fontaine EA, Taylor-Robinson D, Hanna NF, Coufalik ED: Anaerobes in men with urethritis. Br J Vener Dis 58:321–326, 1982.
Storz J: Psittacosis agents as cause of arthritis in cattle and sheep. Vet Med Rev 2/3:125–139, 1967.
Taylor-Robinson D, Taylor GL: Do mycoplasmas cause rheumatic disease? In: Infection and Immunity in the Rheumatic Diseases. DC Dumond (ed.). Blackwell, London, 1976, p. 177–186.
Taylor-Robinson D, Gumpel JM, Hill A, Swannell AJ: Isolation of Mycoplasma pneumoniae from the synovial fluid of a hypogammaglobulinaemic patient in a survey of patients with inflammatory polyarthritis. Ann Rheum Dis 37:180–182, 1978.
Johnstone CLW, Webster ADB, Taylor-Robinson D, Rapaport G, Hughes GRV: Primary late-onset hypogammaglobulinaemia associated with inflammatory polyarthritis and septic arthritis due to Mycoplasma pneumoniae. Ann Rheum Dis 42:108–110, 1983.
So AKL, Furr PM, Taylor-Robinson D, Webster ADB: Arthritis caused by Mycoplasma salivarium in hypogammaglobulinaemia. Br Med J 286:762–763, 1983.
Ford DK: Non-gonococcal urethritis and Reiter’s syndrome: Personal experience with etiological studies during fifteen years. Can Med Assoc J 99:900–910, 1968.
Schachter J, Dawson CR: Comparative efficiency of various diagnostic methods for chlamydial infection. In: Non-gonococcal urethritis and related infections. KK Holmes and D Hobson (eds.). American Society for Microbiology, Washington D.C., 1977, p. 337–341.
Keat AC, Thomas BJ, Taylor-Robinson D: Chlamydial infection in the aetiology of arthritis. Br Med Bull 39:168–174, 1983.
Ford DK, McCadlish L: Isolation of TRIC agents from the human genital tract. Br J Vener Dis 45:44–46, 1969.
Kousa MJ, Saikku P, Richmond S, Lassus A: Frequent association of chlamydial infection with Reiter’s syndrome. Sex Transm Dis 5:57–61, 1978.
Dienes L, Ropes MW, Smith WE, Madoff S, Bauer W: The role of PPLO’s in genitourinary and joint diseases. I. N Engl J Med 238:509–515, 1948.
Warthin TA: Reiter’s syndrome. Am J Med 4:827–835, 1948.
Levy B: Arthritis in venereal disease with particular reference to aetiology. Med J Malaya 5:4248, 1950.
Kuzell WC, Mankle EA: Cultivation of pleuropneumonia-like organisms in Reiter’s syndrome including one instance of laboratory cross-infection. Ann N Y Acad Sci 79:650–657, 1960.
Kleineberger-Nobel E: Pleuropneumonia-like organisms in genital infections. Br Med J 1:19–23, 1959.
Ford DK, Rasmussen G: Relationship between genitourinary infection and complicating arthritis. Arthr Rheum 7:220–227, 1964.
Csonka GW, Williams REO, Corse J: T-strain mycoplasmas in non-gonococcal urethritis. Ann N Y Acad Sci 143:794–798, 1967.
Ford DK: Relationships between mycoplasma and the aetiology of non-gonococcal urethritis and Reiter’s syndrome. Ann N Y Acad Sci 143:501–504, 1967.
Martin DH, Pollock S, Kuo CC, Wang S-P, Brunham RC, Holmes KK: Urethral chlamydial infections in men with Reiter’s syndrome. In: Chlamydial Infections (Fernstrom Foundation Series, Vol 2), P-A Mârdh et al. (eds.). Elsevier Biomedical, Amsterdam, 1982, p. 107–110.
Csonka GW, Furness G: A study of the aetiology of non-gonococcal urethritis and Reiter’s syndrome. Br J Vener Dis 36:181–184, 1960.
Claus G, McEwen C, Brunner T, Tsampatlis G: Attempted virus isolation from the genital tract in Reiter’s syndrome. Br J Vener Dis 40:170–173, 1964.
Viswalingam ND, Wishart MS, Woodland RM: Adult chlamydial ophthalmia (paratrachoma). Br Med Bull 39:123–127, 1983.
Hobson D, Rees E, Viswalingam ND: Chlamydial infections in neonates and older children. Br Med Bull 39:128–132, 1983.
Schachter J, Dawson CR: Human chlamydial infections. PSG publishing company, Littleton, MA, 1978, p. 141–146.
Ostler HB, Dawson CR, Schachter J, Engleman EP: Reiter’s syndrome. Am J Ophthalmol 71: 986–991, 1971.
Schachter J, Dawson CR, Bates S, Jones P: Evaluation of laboratory methods for detecting acute TRIC agent infection. Am J Ophthalmol 70:375–380, 1970.
Dawson CR, Schachter J, Ostler HB, Gilbert RM, Smith DE, Engleman EP: Inclusion conjunctivitis and Reiter’s syndrome in a married couple. Arch Ophthalmol 83:300–306, 1970.
Mark DB, McCulley JB: Reiter’s keratitis. Arch Ophthalmol 100:781–784, 1982.
Darougar S, Woodland RM, Forsey T, Cubitt S, Alani J, Jones BR: Isolation of chlamydia from ocular infections. In: Non-gonococcal Urethritis and Related Infections. D Hobson and KK Holmes (eds.). American Society for Microbiology, Washington D.C. 1977, p. 295–298.
Holland NC: Results of tests for chlamydia in patients suffering from acute Reiter’s disease compared with results of tests of the genital tract and rectum in patients with ocular infection due to TRIC agent. Ann N Y Acad Sci 79:646–649, 1960.
Dunlop EMC, Freedman A, Garland JA, Harper IA, Jones BR, Race JW, du Toit MS, Treharne JD: Infection by Bedsoniae and the possibility of spurious isolation. 2. Genital infection, disease of the eye, Reiter’s disease. Am J Ophthalmol 63:1073–1081, 1967.
Rosenberg AM, Petty RE: Reiter’s disease in children. Am J Dis Child 133:394–398, 1979.
Editorial. Reiter’s syndrome. Lancet II:567, 1979.
Schachter J: Chlamydiae in Reiter’s syndrome. Lancet I:40, 1980.
Kuzell WC, Mankle EA: Cortisone acetate and terramycin in polyarthritis-of rats. Proc Soc Exp Biol Med 74:677–681, 1950.
Butas CA: The isolation of pleuropneumonia-like organisms from two cases of polyarthritis. Canad J Microbiol 3:419–420, 1957.
Jonsson J: Mycoplasma organisms in synovial fluid from rheumatic joints. Acta Rheum Scand 7:287–303, 1961.
Bartholomew LE: Isolation and characterisation of pleuropneumonia-like organisms from patients with rheumatoid arthritis, SLE and Reiter’s syndrome. Arthr Rheum 8:376–388, 1965.
Ford DK: The relationship of human genital pleuropneumonia-like organisms to arthritis complicating urethritis. Arthr Rheum 3:395–401, 1960.
Lowenthal RM: Virological studies in Reiter’s disease. Br J Vener Dis 49:368–375, 1978.
Grahame R, Armstrong R, Simmons NA, Nims CA, Wilton JMA, Laurent R: Isolation of rubella virus from synovial fluid in five cases of seronegative arthritis. Lancet II:649–651, 1981.
Wang S-P and Grayston JT: Immunological relationships between genital TRIC, lymphogranuloma venereum and related organisms in a new microtiter indirect immunofluorescence test. Am J Ophthalmo1. 367–374, 1970.
Richmond SJ, Caul EO: Single antigen indirect immunofluorescence test for screening venereal disease clinic populations for chlamydial antibodies. In: Non-gonococcal urethritis and related infections. D Hobson and KK Holmes (eds.). American Society for Microbiology, Washington D.C., 1977, p. 259–265.
Treharne JD, Forsey T, Thomas BJ: Chlamydial serology. Br Med Bull 39:194–200, 1983.
Vaughan-Jackson JD, Dunlop EMC, Darougar S, Dwyer RStC, Jones BR: Chlamydial infection. Br J Vener Dis 48:445–451, 1972.
Kinsella TD, Norton WL, Ziff M: Complement fixing antibodies to Bedsonia organisms in Reiter’s syndrome and ankylosing spondylitis. Ann Rheum Dis 27:241–244, 1968.
Schachter J: Complement fixing antibodies to Bedsonia in Reiter’s syndrome, TRIC agent infection, and control groups. Am J Ophthalmol. 71:857–860, 1971.
Keat AC, Thomas BJ, Taylor-Robinson D, Maini RN, Pegrum GD, Scott JT: Evidence of Chlamydia trachomatis infection in sexually acquired reactive arthritis. Ann Rheum Dis 39:431–443,1980.
Vilppula AH, Yli-Kerttula VI, Ahlross ALC, Terho PE: Chlamydial isolations and serology in Reiter’s syndrome. Scand J Rheum 10:181–185, 1981.
Taylor-Robinson D, Thomas BJ, Furr PM, Keat AC: The association of Mycoplasma hominis with arthritis. Sex Transm Dis 10, (Suppl.) 341–344, 1983.
Purcell RH, Taylor-Robinson D, Wong DC, Chanock RM: A color test for the measurement of antibody to the non-acid-forming human Mycoplasma species. Am J Epidemiol 84:51–66, 1966.
Ford DK, da Roza DM, Schuler M: The specificity of synovial mononuclear cell responses to microbiological antigens in Reiter’s syndrome. J Rheum 9:561–567, 1982.
DiGiacomo RF, Gale JL, Wang S-P, Kiviat MD: Chlamydial infection of the male baboon urethra. Br J Vener Dis 51:310–313, 1975.
Darougar S, Monnickendam MA, El-Sheikh H, Treharne JD, Woodland RM, Jones BR: Animal models for the study of chlamydial infections of the eye and genital tract. In: Nongonococcal urethritis and related infections. D Hobson and KK Holmes (eds.). American Society for Microbiology, Washington D.C., 1977, p. 186–198.
Gale JL, DiGiacomo RF, Kiviat MD, Wang S-P, Bowie WR: Experimental non-human primate urethral infection with Chlamydia trachomatis and ureaplasma (T-mycoplasma). In: Nongonococcal urethritis and related infections. D Hobson and KK Holmes (eds.). American Society for Microbiology, Washington D.C., 1977, p. 205–212.
Jacobs NF, Arum ES, Kraus SJ: Experimental infection of the chimpanzee urethra and pharynx with Chlamydia trachomatis. Sex Transm Dis 5:132–136, 1978.
Barron AL, White HJ, Rank RG, Soloff BL, Moses EB: A new animal model for the study of Chlamydia trachomatis genital infections: Infection of mice with the agent of mouse pneumonitis. J Infect Dis 143:63–66, 1981.
Taylor-Robinson D, Purcell RH, London WT, Sly DL, Thomas BJ, Evans RT: Microbiological, serological and histopathological features of experimental Chlamydia trachomatis urethritis in chimpanzees. Br J Vener Dis 57:36–40, 1981.
Tuffrey M, Taylor-Robinson D: Progesterone as a key factor in the development of a mouse model for genital-tract infection with Chlamydia trachomatis. FEMS Microbiol Lett 12:111–115, 1981.
Jones JPJ, Schachter J, Meyer KF: Experimental Bedsonia arthritis. Arthr Rheum 9:515–516 (abstr), 1966.
Smith DE, James PG, Schachter J, Engleman EP, Meyer KF: Experimental Bedsonia arthritis. Arthr Rheum 16:21–29, 1973.
Smith DE, James PG, Schachter J, Engleman EP, Meyer KF: Experimental Bedsonia arthritis in rabbits. Arthr Rheum 11:511, 1968.
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Keat, A.C., Thomas, B.J. (1985). Sexually acquired reactive arthritis. In: Taylor-Robinson, D. (eds) Clinical Problems in Sexually Transmitted Diseases. New Perspectives in Clinical Microbiology, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5014-6_4
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