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Cardiovascular Effects of Intravenous Anesthetic Agents

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Animal Models in Cardiovascular Research

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Abstract

The most commonly used anesthetic agents of this kind are the barbiturates. The duration of action of these agents is tied to their fat solubility. Since the thiobarbiturates are more fat soluble (classified as ultra-short acting), they provide a surgical plane of anesthesia for less time than the short acting agents such as pentobarbital sodium. Most of these drugs are, however, metabolized at about the same rate. If the ultra-short acting barbiturates are used and additional drug is given to achieve a longer duration of anesthesia, the pool of unmetabolized drugs is expanded and the recovery period can be very prolonged.

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  1. Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A & M University, College Station, 77843-4466, Texas, USA

    David R. Gross D.V.M., Ph.D.

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  1. David R. Gross D.V.M., Ph.D.
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© 1985 Martinus Nijhoff Publishers, Dordrecht

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Gross, D.R. (1985). Cardiovascular Effects of Intravenous Anesthetic Agents. In: Animal Models in Cardiovascular Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5006-1_6

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  • DOI: https://doi.org/10.1007/978-94-009-5006-1_6

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