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Iatrogenic Models for Studying Heart Disease

  • Chapter
Animal Models in Cardiovascular Research

Abstract

Research associated with heart failure has, over the years, been aimed at three general areas: 1) The identification, characterization and quantification of injured tissue, including the so-called “border zone controversy”. 2) The testing and evaluation of a large variety of interventions, pharmacologic and other, of potential therapeutic value. 3) Studies designed to evaluate the dynamics and mechanisms of heart failure, per se. The common requirement of all studies of this nature is an adequate model of heart failure. A wide variety of models have been used, each of which generates a characteristic type or a specific phase of failure.

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  1. Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A & M University, College Station, 77843-4466, Texas, USA

    David R. Gross D.V.M., Ph.D.

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  1. David R. Gross D.V.M., Ph.D.
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© 1985 Martinus Nijhoff Publishers Dordrecht

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Gross, D.R. (1985). Iatrogenic Models for Studying Heart Disease. In: Animal Models in Cardiovascular Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5006-1_12

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  • DOI: https://doi.org/10.1007/978-94-009-5006-1_12

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