Abstract
With use of a bisyncitial model of the heart, it is shown that time integrals of QRS and QSR-T are related to the amplitude (A), area (µ), and activation time (τ) of the cellular action potential (AP) on the closed surface surrounding the ventricles. For the normal heart, solution of the inverse problem would give µ and τ on the heart surface, and by interpolation in the myocardium, allowing reconstruction of the AP. In the case of ischemia and infarction, µ and A τ would be available, which, while not defining the AP, might provide valuable information. Necrosis introduces an unknown perturbation.
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Geselowitz, D.B. (1985). A bidomain model of the ECG: Time integrals and the inverse problem. In: Sideman, S., Beyar, R. (eds) Simulation and Imaging of the Cardiac System. Developments in Cardiovascular Medicine, vol 43. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4992-8_20
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DOI: https://doi.org/10.1007/978-94-009-4992-8_20
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8710-0
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