Abstract
A computer model for calculating left epicardial coronary blood flow has been developed. This model employs a finite-branching geometry of the coronary vasculature together with the one-dimensional, unsteady equations for flow with friction. The epicardial coronary geometry includes the left main bifurcation and a selected number of smaller branches, each of which terminates in a resistance which is related to intramyocardial compression through a linear dependence on left ventricular pressure. The elastic properties of the epicardial arteries are taken to be non-linear and are prescribed by specifying the local small-disturbance wave speed. Calculations using this model predict pressure and flow waveform development and allow for the systematic investigation of the dependence of coronary flow on various parameters, e.g. peripheral resistance, wall properties, branching pattern, etc. Reasonable comparison between calculations and earlier experiments in horses has been obtained.
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© 1985 Martinus Nijhoff Publishers, Dordrecht
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Nerem, R.M., Rooz, E., Wiesner, T.F. (1985). A method for calculating time-dependent epicardial coronary blood flow. In: Sideman, S., Beyar, R. (eds) Simulation and Imaging of the Cardiac System. Developments in Cardiovascular Medicine, vol 43. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4992-8_18
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DOI: https://doi.org/10.1007/978-94-009-4992-8_18
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8710-0
Online ISBN: 978-94-009-4992-8
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